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  2. Long interspersed elements, type 1(LINE-1, L1) are the most abundant and only active autonomous retrotransposons in the human genome. Native L1 elements are inefficiently expressed because of a transcription e...

    Authors: Wenfeng An, Lixin Dai, Anna Maria Niewiadomska, Alper Yetil, Kathryn A O'Donnell, Jeffrey S Han and Jef D Boeke
    Citation: Mobile DNA 2011 2:2
    Content type: Research Published on:

  5. Completed genome projects have revealed an astonishing diversity of transposable genetic elements, implying the existence of novel element families yet to be discovered from diverse life forms. Concurrently, s...

    Authors: Maria I Pajunen, Tiina S Rasila, Lotta J Happonen, Arja Lamberg, Saija Haapa-Paananen, Saija Kiljunen and Harri Savilahti
    Citation: Mobile DNA 2010 1:24
    Content type: Research Published on:

  7. Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to...

    Authors: Nicholas A Wallace, Victoria P Belancio, Zach Faber and Prescott Deininger
    Citation: Mobile DNA 2010 1:22
    Content type: Research Published on:

  9. An international conference on mobile DNA was held 24-28 April 2010 in Montreal, Canada. Sponsored by the American Society for Microbiology, the conference's goal was to bring together researchers from around ...

    Authors: George Chaconas, Nancy Craig, M Joan Curcio, Prescott Deininger, Cedric Feschotte, Henry Levin, Phoebe A Rice and Daniel F Voytas
    Citation: Mobile DNA 2010 1:20
    Content type: Meeting Report Published on:

  10. Retrotransposons are abundant components of plant genomes, and although some plant retrotransposons have been used as insertional mutagens, these mobile genetic elements have not been widely exploited for plan...

    Authors: Yi Hou, Jyothi Rajagopal, Phillip A Irwin and Daniel F Voytas
    Citation: Mobile DNA 2010 1:19
    Content type: Research Published on:

  13. Tight regulation of transposition activity is essential to limit damage transposons may cause by generating potentially lethal DNA rearrangements. Assembly of a bona fide protein-DNA complex, the transpososome...

    Authors: Philippe Rousseau, Catherine Tardin, Nathalie Tolou, Laurence Salomé and Mick Chandler
    Citation: Mobile DNA 2010 1:16
    Content type: Research Published on:

  15. The yeast retrotransposon Ty3 forms stable virus-like particles. Gag3, the major structural protein, is composed of capsid, spacer and nucleocapsid domains. The capsid domain of Gag3 was previously modeled as ...

    Authors: Min Zhang, Liza SZ Larsen, Becky Irwin, Virginia Bilanchone and Suzanne Sandmeyer
    Citation: Mobile DNA 2010 1:14
    Content type: Short Report Published on:

  16. The ends of chromosomes, termed telomeres consist of repetitive DNA. The telomeric sequences shorten with cell division and, when telomeres are critically abbreviated, cells stop proliferating. However, in can...

    Authors: Kazutoshi Yoshitake, Hideyuki Aoyagi and Haruhiko Fujiwara
    Citation: Mobile DNA 2010 1:13
    Content type: Research Published on:

  17. Rotifers of the class Bdelloidea are microscopic freshwater invertebrates best known for: their capacity for anhydrobiosis; the lack of males and meiosis; and for the ability to capture genes from other non-me...

    Authors: Eugene A Gladyshev and Irina R Arkhipova
    Citation: Mobile DNA 2010 1:12
    Content type: Research Published on:

  22. L1s are one of the most successful autonomous mobile elements in primate genomes. These elements comprise as much as 17% of primate genomes with the majority of insertions occurring via target primed reverse t...

    Authors: Thomas J Meyer, Deepa Srikanta, Erin M Conlin and Mark A Batzer
    Citation: Mobile DNA 2010 1:7
    Content type: Research Published on:

  23. How new forms arise in nature has engaged evolutionary biologists since Darwin's seminal treatise on the origin of species. Transposable elements (TEs) may be among the most important internal sources for intr...

    Authors: Alexander Belyayev, Ruslan Kalendar, Leonid Brodsky, Eviatar Nevo, Alan H Schulman and Olga Raskina
    Citation: Mobile DNA 2010 1:6
    Content type: Research Published on:

  24. PIF/Harbinger is the most recently discovered DNA transposon superfamily and is now known to populate genomes from fungi to plants to animals. Mobilization of superfamily members requires two separate element-enc...

    Authors: C Nathan Hancock, Feng Zhang and Susan R Wessler
    Citation: Mobile DNA 2010 1:5
    Content type: Research Published on:

  25. Scientific history has had a profound effect on the theories of evolution. At the beginning of the 21st century, molecular cell biology has revealed a dense structure of information-processing networks that us...

    Authors: James A Shapiro
    Citation: Mobile DNA 2010 1:4
    Content type: Review Published on:
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Mobile DNA

ISSN: 1759-8753