The role of DNA methylation in aging has been widely studied. However, epigenetic mutations, here defined as aberrant methylation levels compared to the distribution in a population, are less understood. For this Methodology, our authors developed whole-cell, cytoplasmic and nuclear RNA-Seq datasets from 22Rv1 prostate cancer cells to test the influence of different preparations on the quality and effort needed to measure L1 expression.
Featured article: Dfam updated!
Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. This expansion demonstrates the utility of many of Dfam’s new features and provides insight into the long term challenges ahead for improving de novo generated transposable element datasets. Read it here!
Featured series: Transposable Elements in Model Organisms
We are proud to present a new series of review papers focused on transposable elements (TE) in model organisms. This series will deliver a comprehensive and even coverage of the diversity of TEs populating the model species; outstanding questions and future directions with the study of TEs in species; and much more!
Mobile DNA is proud to share information about the following conferences/meetings which will be of interest to our readership:
FASEB's "The Mobile DNA Conference: Evolution, Diversity, and Impact", 8th-9th June 2021
EMBL's "The Mobile Genome: Genetic and Physiological Impacts of Transposable Elements", 29 Aug - 1 Sep 2021
The 2nd AsiaEvo Conference, 16-19 Aug 2021
Call for Papers: Endogenous Retroviruses in Evolution and Disease
The Editors of Mobile DNA and Retrovirology extend an invitation to submit original research articles related to endogenous retroviruses to their new collection: Endogenous Retroviruses in Evolution and Disease.
Open for submissions: May 24, 2019
Closed for submissions: January 2021
Submit an article to Mobile DNA for the series.
Repository for all published Review articles. Contributions from some of the leading researchers working with mobile DNA.
Mobile DNA Tools
Repository for all published articles on softwares, databases, and methodologies.
Transposable Elements in Model Organisms
Edited by the Editors-in-Chief
Endogenous Retroviruses in Evolution and Disease
Cross-journal series with Retrovirology. Edited by the Editors-in-Chief of Mobile DNA and Retrovirology.
Transposable Elements in Model Organisms (coming soon)
Edited by the Editors-in-Chief
Keystone Symposium: Mobile Genetic Elements and Genome Evolution
Edited by: Henry Levin, Parmit Singh
Mobile genetic elements in biotechnology
Edited by: Henry Levin, Thomas Eickbush, Marlene Belfort, Nancy Craig, Cedric Feschotte
Mobile introns review series
Edited by: Thomas Eickbush, Marlene Belfort, Nancy Craig, Daniel Voytas
The Editors-in-Chief of Mobile DNA welcome authors to send any pre-submission inquiries they might have to the Editorial Email address, which can be found here by clicking on "Contact Us" (upper left side of page). We ask that you please include “Pre-submission inquiry” in the subject line of your email and that you include the title and abstract of your proposed submission within the message. Our Editors will do their best to respond to you in a timely manner.
Highlights from recent literature on mobile elements, selected by the Editors-in-Chief.
A Long, Fulfilling Career in Human Genetics [Annu Rev Genomics Hum Genet. 2021] PubMed
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation [Nat Commun. 2021] PubMed
Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3 [Cell Stem Cell. 2021] PubMed
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues [Proc Natl Acad Sci U S A. 2021] PubMed
A cis-regulatory atlas in maize at single-cell resolution [Cell. 2021] PubMed
Irina Arkhipova, Marine Biological Laboratory at Woods Hole
Jeffrey Bennetzen, University of Georgia, USA
Kathleen Burns, Dana-Farber Cancer Institute at Harvard Medical School, USA
Pascale Lesage, INSERM, France
In 2019, we welcomed our new Associate Editors:
Orsolya Barabas, European Molecular Biology Laboratory (EMBL), Germany
Gael Cristofari, Institut National de la Santé et de la Recherche Médicale, France
Adam Ewing, Mater Research Institute-University of Queensland, Australia
Clément Gilbert, CNRS, Université Paris Saclay, France
Molly G Hammell, Cold Spring Harbor Laboratory, USA
Damon R Lisch, Purdue University, USA
Joe Peters, Cornell University, USA
Phoebe Rice, The University of Chicago, USA
Aims and scope
Mobile DNA is an online, peer-reviewed, open access journal that publishes articles providing novel insights into the function, biological impact, and evolution of transposable elements in any organism. Topics related to transposable elements may include genetic or epigenetic variation, genome rearrangements, mechanisms, patterns and processes of transposition, and the role of mobile elements in host genome evolution.Mobile DNA aims to understand:
- mechanisms of intra- and intergenomic mobility via genetic, comparative genomic, biochemical and structural approaches
- regulation of DNA rearrangements by the environment and during development
- how DNA restructuring reshapes cellular function and organism evolution
- the role of transposable elements in disease in a variety of organisms
- host—element interaction and genetic/epigenetic regulatory networks
Mobile DNA reflects the need for a journal that spans all aspects of specialized recombination, from structure and mechanism to evolutionary impact. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols, and related biocomputational tools.
Updated monthly, check out the newest published research on transposable elements in the TE Digest on Alexander Suh of Uppsala University's Genomicrocosm page here.
Annual Journal Metrics
43 days to first decision for reviewed manuscripts only
37 days to first decision for all manuscripts
116 days from submission to acceptance
21 days from acceptance to publication
3.161 - 2-year Impact Factor
5.173 - 5-year Impact Factor
0.958 - Source Normalized Impact per Paper (SNIP)
2.379 - SCImago Journal Rank (SJR)
426 Altmetric Mentions