Mobile DNA

McClintock image credit: Smithsonian Institution/Science Service; Restored by Adam Cuerden

Transposon Day 2022

Mobile DNA celebrates Transposon Day every June 16th, to commemorate the birthdate of the founder of transposable elements research, Barbara McClintock (1902-1992). This day was designated to honor her legacy and draw attention to the important research that has changed the way researchers think about evolution, disease, and genomics.

Featured article: A beginner’s guide to manual curation of transposable elements

Schematic representation of RM2 output In the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigate these fascinating genomic elements. This article attempts to fill the gap between automated annotation of TEs and the generation of a manually curated library by providing a set of detailed computer protocols, software recommendations and video tutorials for those aiming to manually curate TEs. Read full article here!

Featured series: Transposable Elements in Model Organisms

New Content Item We are proud to present a new series of review papers focused on transposable elements (TE) in model organisms. This series will deliver a comprehensive and even coverage of the diversity of TEs populating the model species; outstanding questions and future directions with the study of TEs in species; and much more!

Recent
Most accessed

Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells

Authors: Giulia Irene Maria Pasquesi, Conor J. Kelly, Andrea D. Ordonez and Edward B. Chuong

Content type: Research 6 September 2022
SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution

Authors: Emily C. Stow, Melody Baddoo, Alexis J. LaRosa, Dawn LaCoste, Prescott Deininger and Victoria Belancio

Content type: Research 26 August 2022
Multiple horizontal transfers of a Helitron transposon associated with a parasitoid wasp

Authors: Pedro Heringer and Gustavo C. S. Kuhn

Content type: Brief Report 19 August 2022
Genomic analysis reveals the role of integrative and conjugative elements in plant pathogenic bacteria

Authors: Jéssica Catarine Silva de Assis, Osiel Silva Gonçalves, Alexia Suellen Fernandes, Marisa Vieira de Queiroz, Denise Mara Soares Bazzolli and Mateus Ferreira Santana

Content type: Research 12 August 2022
Amplification of LTRs of extrachromosomal linear DNAs (ALE-seq) identifies two active Oryco LTR retrotransposons in the rice cultivar Dongjin

Authors: Hyunjin Koo, Soomin Kim, Hyun-Seung Park, Sang-Ji Lee, Nam-Chon Paek, Jungnam Cho and Tae-Jin Yang

Content type: Brief Report 13 June 2022

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Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions

Authors: Jeffrey S Han

Content type: Review 12 May 2010
The expanding universe of transposon technologies for gene and cell engineering

Authors: Zoltán Ivics and Zsuzsanna Izsvák

Content type: Review 7 December 2010
Mobile DNA and evolution in the 21st century

Authors: James A Shapiro

Content type: Review 25 January 2010
Mobilizing diversity: transposable element insertions in genetic variation and disease

Authors: Kathryn A O'Donnell and Kathleen H Burns

Content type: Review 2 September 2010
Transposable element detection from whole genome sequence data

Authors: Adam D. Ewing

Content type: Review 29 December 2015

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Editors' Picks

Highlights from recent literature on mobile elements, selected by the Editors-in-Chief.

Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. [Proc Natl Acad Sci U S A. 2022] PubMed

Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1. [J Virol. 2022] PubMed

Uncontrolled transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of Cryptococcus neoformans. [Nat Microbiol. 2022] PubMed

Telomere transposon takeover in Cryptococcus. [Nat Microbiol. 2022] PubMed

Hijacking of transcriptional condensates by endogenous retroviruses. [Nat Genet. 2022] PubMed

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Aims and scope

Mobile DNA is an online, peer-reviewed, open access journal that publishes articles providing novel insights into the function, biological impact, and evolution of transposable elements in any organism. Topics related to transposable elements may include genetic or epigenetic variation, genome rearrangements, mechanisms, patterns and processes of transposition, and the role of mobile elements in host genome evolution.

Mobile DNA aims to understand:

mechanisms of intra- and intergenomic mobility via genetic, comparative genomic, biochemical and structural approaches
regulation of DNA rearrangements by the environment and during development
how DNA restructuring reshapes cellular function and organism evolution
the role of transposable elements in disease in a variety of organisms
host—element interaction and genetic/epigenetic regulatory networks

Mobile DNA reflects the need for a journal that spans all aspects of specialized recombination, from structure and mechanism to evolutionary impact. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols, and related biocomputational tools.

Editors-in-Chief

Irina Arkhipova, Marine Biological Laboratory at Woods Hole
Kathleen Burns, Dana-Farber Cancer Institute at Harvard Medical School, USA
Pascale Lesage, INSERM, France

Our Associate Editors:
Orsolya Barabas, European Molecular Biology Laboratory (EMBL), Germany
Gael Cristofari, Institut National de la Santé et de la Recherche Médicale, France
Adam Ewing, Mater Research Institute-University of Queensland, Australia
Clément Gilbert, CNRS, Université Paris Saclay, France
Molly G Hammell, Cold Spring Harbor Laboratory, USA
Damon R Lisch, Purdue University, USA
Joe Peters, Cornell University, USA
Phoebe Rice, The University of Chicago, USA
Vincent Colot, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), France

Links to Useful TE Community Resources

Transposable elements labs directory

Women in TEs (maintained by Cedric Feschotte)

Job vacancies

Transposons Worldwide SLACK Page (Managed by Rebecca Berrens)

Mobile DNA Tools Collection

TE digest (Managed by Alexander Suh)

TE Hub

TnCentral

ISfinder (Insertion Sequence database)

Upcoming meetings

Mobile DNA is proud to share information about the following conferences/meetings which will be of interest to our readership:

The Mobile DNA Conference: Evolution, Diversity, and Impact

June 5–9, 2022, Malahide, Ireland

Mobile DNA

Transposon Day 2022

Featured article: A beginner’s guide to manual curation of transposable elements

Featured series: Transposable Elements in Model Organisms

Transcriptional dynamics of transposable elements in the type I IFN response in Myotis lucifugus cells

SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution

Multiple horizontal transfers of a Helitron transposon associated with a parasitoid wasp

Genomic analysis reveals the role of integrative and conjugative elements in plant pathogenic bacteria

Amplification of LTRs of extrachromosomal linear DNAs (ALE-seq) identifies two active Oryco LTR retrotransposons in the rice cultivar Dongjin

Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions

The expanding universe of transposon technologies for gene and cell engineering

Mobile DNA and evolution in the 21st century

Mobilizing diversity: transposable element insertions in genetic variation and disease

Transposable element detection from whole genome sequence data

Editors' Picks

Aims and scope

Editors-in-Chief

Links to Useful TE Community Resources

Upcoming meetings

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Annual Journal Metrics

Mobile DNA

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