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Transposon Day 2022

Mobile DNA celebrates Transposon Day every June 16th, to commemorate the birthdate of the founder of transposable elements research, Barbara McClintock (1902-1992). This day was designated to honor her legacy and draw attention to the important research that has changed the way researchers think about evolution, disease, and genomics.

Featured article: A beginner’s guide to manual curation of transposable elements

Schematic representation of RM2 outputIn the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigate these fascinating genomic elements. This article attempts to fill the gap between automated annotation of TEs and the generation of a manually curated library by providing a set of detailed computer protocols, software recommendations and video tutorials for those aiming to manually curate TEs. Read full article here!

Featured series: Transposable Elements in Model Organisms

New Content ItemWe are proud to present a new series of review papers focused on transposable elements (TE) in model organisms. This series will deliver a comprehensive and even coverage of the diversity of TEs populating the model species; outstanding questions and future directions with the study of TEs in species; and much more

Editors' Picks

Highlights from recent literature on mobile elements, selected by the Editors-in-Chief.

Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. [Proc Natl Acad Sci U S A. 2022] PubMed

Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1. [J Virol. 2022] PubMed

Uncontrolled transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of Cryptococcus neoformans. [Nat Microbiol. 2022] PubMed

Telomere transposon takeover in Cryptococcus. [Nat Microbiol. 2022] PubMed

Hijacking of transcriptional condensates by endogenous retroviruses. [Nat Genet. 2022] PubMed

View all editors' picks

Aims and scope

Mobile DNA is an online, peer-reviewed, open access journal that publishes articles providing novel insights into the function, biological impact, and evolution of transposable elements in any organism. Topics related to transposable elements may include genetic or epigenetic variation, genome rearrangements, mechanisms, patterns and processes of transposition, and the role of mobile elements in host genome evolution.

Mobile DNA aims to understand:
  • mechanisms of intra- and intergenomic mobility via genetic, comparative genomic, biochemical and structural approaches
  • regulation of DNA rearrangements by the environment and during development
  • how DNA restructuring reshapes cellular function and organism evolution
  • the role of transposable elements in disease in a variety of organisms
  • host—element interaction and genetic/epigenetic regulatory networks

Mobile DNA reflects the need for a journal that spans all aspects of specialized recombination, from structure and mechanism to evolutionary impact. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols, and related biocomputational tools.

Editors-in-Chief

Irina Arkhipova, Marine Biological Laboratory at Woods Hole
Kathleen Burns, Dana-Farber Cancer Institute at Harvard Medical School, USA
Pascale Lesage, INSERM, France
 

Our Associate Editors: 
Orsolya Barabas, European Molecular Biology Laboratory (EMBL), Germany
Gael Cristofari, Institut National de la Santé et de la Recherche Médicale, France 
Adam Ewing, Mater Research Institute-University of Queensland, Australia
Clément Gilbert, CNRS, Université Paris Saclay, France 
Molly G Hammell, Cold Spring Harbor Laboratory, USA
Damon R Lisch, Purdue University, USA
Joe Peters, Cornell University, USA
Phoebe Rice, The University of Chicago, USA 
Vincent Colot, Institut de Biologie de l'Ecole Normale Supérieure (IBENS), France

Links to Useful TE Community Resources

Transposable elements labs directory

Women in TEs (maintained by Cedric Feschotte)

Job vacancies

Transposons Worldwide SLACK Page (Managed by Rebecca Berrens)

Mobile DNA Tools Collection

TE digest (Managed by Alexander Suh)

TE Hub

TnCentral

ISfinder (Insertion Sequence database)

Upcoming meetings

Mobile DNA is proud to share information about the following conferences/meetings which will be of interest to our readership:


The Mobile DNA Conference: Evolution, Diversity, and Impact

June 5–9, 2022, Malahide, Ireland


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