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Featured article - The case for not masking away repetitive DNA

In the course of analyzing whole-genome data, it is common practice to mask or filter out repetitive regions of a genome, such as transposable elements and endogenous retroviruses, in order to focus only on genes and thus simplify the results. This Commentary is a plea from one member of the Mobile DNA community to all gene-centric researchers: please do not ignore the repetitive fraction of the genome. 

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Review collection
All Reviews
Repository for all published Review articles. Contributions from some of the leading researchers working with mobile DNA.

Article collection
Mobile DNA Tools
Repository for all published articles on softwares, databases, and methodologies.

2015

Thematic series

Keystone Symposium: Mobile Genetic Elements and Genome Evolution
Edited by: Henry Levin, Parmit Singh

2014

Review series
Mobile genetic elements in biotechnology
Edited by: Henry Levin, Thomas Eickbush, Marlene Belfort, Nancy Craig, Cedric Feschotte

2013

Review series
Mobile introns review series
Edited by: Thomas Eickbush, Marlene Belfort, Nancy Craig, Daniel Voytas

Editors' picks

Highlights from recent literature on mobile elements, selected by the Editors-in-Chief.

Contrasted patterns of evolution of the LINE-1 retrotransposon in perissodactyls: the history of a LINE-1 extinction. [Mob DNA. 2018] PubMed

The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. [Mob DNA. 2018] PubMed

Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering. [Nucleic Acids Res. 2018] PubMed

A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. [Mob DNA. 2018] PubMed

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis. [Genome Res. 2018] PubMed

View all editors' picks​​​​​​​

Editors-in-Chief

Marlene Belfort, University at Albany
Cédric Feschotte, Cornell University
Haig Kazazian, Johns Hopkins University
Henry Levin, NIH

Aims and scope

Mobile DNA is an open access, peer-reviewed journal that publishes articles providing novel insights into DNA rearrangements in all organisms, ranging from transposition and other types of recombination mechanisms to patterns and processes of mobile element and host genome evolution. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols.

Pre-submission Inquiries

The Editors-in-Chief of Mobile DNA welcome authors to send any pre-submission inquiries they might have to the Editorial Email address, which can be found here. We ask that you please include “Pre-submission inquiry” in the subject line of your email and that you include the title and abstract of your proposed submission within the message. Our Editors will do their best to respond to you in a timely manner.

Latest Tweets

Transposable Elements Conference

Cold Spring Harbor Laboratory will be holding its second meeting on “Transposable Elements” November 1-8, 2018 at Cold Spring Harbor, NY.  The primary goal of the meeting is to provide a forum for presentation of the latest research into transposable elements, and will consist of six oral sessions plus one poster session.  Sessions will be made up of invited talks and talks selected from the openly submitted abstracts. 

The organizers for this conference are:

Rob Martienssen, Cold Spring Harbor Laboratory
Phoebe Rice, University of Chicago
Donald Rio, University of California, Berkeley

The abstract deadline is August 10, 2018.

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