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  1. Content type: Short Report

    Transposons, segments of DNA that can mobilize to other locations in a genome, are often used for insertion mutagenesis or to generate priming sites for sequencing of large DNA molecules. For both of these use...

    Authors: Brian Green, Christiane Bouchier, Cécile Fairhead, Nancy L Craig and Brendan P Cormack

    Citation: Mobile DNA 2012 3:3

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  2. Content type: Research

    Transposable elements (TEs) are major contributors to genome evolution. One factor that influences their evolutionary dynamics is whether their host reproduces through selfing or through outcrossing. According...

    Authors: Nicole de la Chaux, Takashi Tsuchimatsu, Kentaro K Shimizu and Andreas Wagner

    Citation: Mobile DNA 2012 3:2

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  3. Content type: Research

    Transposition in IS3, IS30, IS21 and IS256 insertion sequence (IS) families utilizes an unconventional two-step pathway. A figure-of-eight intermediate in Step I, from asymmetric single-strand cleavage and joinin...

    Authors: Leslie A Lewis, Mekbib Astatke, Peter T Umekubo, Shaheen Alvi, Robert Saby, Jehan Afrose, Pedro H Oliveira, Gabriel A Monteiro and Duarte MF Prazeres

    Citation: Mobile DNA 2012 3:1

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  4. Content type: Research

    The Sleeping Beauty (SB) transposon system has been used for germline transgenesis of the diploid frog, Xenopus tropicalis. Injecting one-cell embryos with plasmid DNA harboring an SB transposon substrate togethe...

    Authors: Donald A Yergeau, Clair M Kelley, Emin Kuliyev, Haiqing Zhu, Michelle R Johnson Hamlet, Amy K Sater, Dan E Wells and Paul E Mead

    Citation: Mobile DNA 2011 2:15

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  5. Content type: Research

    The two-step transposition pathway of insertion sequences of the IS3 family, and several other families, involves first the formation of a branched figure-of-eight (F-8) structure by an asymmetric single strand c...

    Authors: Leslie A Lewis, Mekbib Astatke, Peter T Umekubo, Shaheen Alvi, Robert Saby and Jehan Afrose

    Citation: Mobile DNA 2011 2:14

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  6. Content type: Research

    The human genome contains approximately one million Alu elements which comprise more than 10% of human DNA by mass. Alu elements possess direction, and are distributed almost equally in positive and negative stra...

    Authors: George W Cook, Miriam K Konkel, James D Major III, Jerilyn A Walker, Kyudong Han and Mark A Batzer

    Citation: Mobile DNA 2011 2:10

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  7. Content type: Research

    Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathoge...

    Authors: Guillaume Cambray, Neus Sanchez-Alberola, Susana Campoy, Émilie Guerin, Sandra Da Re, Bruno González-Zorn, Marie-Cécile Ploy, Jordi Barbé, Didier Mazel and Ivan Erill

    Citation: Mobile DNA 2011 2:6

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  8. Content type: Methodology

    The transposon-based gene delivery technique is emerging as a method of choice for gene therapy. The Sleeping Beauty (SB) system has become one of the most favored methods, because of its efficiency and its rando...

    Authors: Orsolya Kolacsek, Virág Krízsik, Anita Schamberger, Zsuzsa Erdei, Ágota Apáti, György Várady, Lajos Mátés, Zsuzsanna Izsvák, Zoltán Ivics, Balázs Sarkadi and Tamás I Orbán

    Citation: Mobile DNA 2011 2:5

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    The Erratum to this article has been published in Mobile DNA 2013 4:11

  9. Content type: Research

    The centromeric and pericentromeric regions of plant chromosomes are colonized by Ty3/gypsy retrotransposons, which, on the basis of their reverse transcriptase sequences, form the chromovirus CRM clade. Despi...

    Authors: Pavel Neumann, Alice Navrátilová, Andrea Koblížková, Eduard Kejnovský, Eva Hřibová, Roman Hobza, Alex Widmer, Jaroslav Doležel and Jiří Macas

    Citation: Mobile DNA 2011 2:4

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  10. Content type: Research

    Long interspersed elements, type 1(LINE-1, L1) are the most abundant and only active autonomous retrotransposons in the human genome. Native L1 elements are inefficiently expressed because of a transcription e...

    Authors: Wenfeng An, Lixin Dai, Anna Maria Niewiadomska, Alper Yetil, Kathryn A O'Donnell, Jeffrey S Han and Jef D Boeke

    Citation: Mobile DNA 2011 2:2

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  11. Content type: Research

    Completed genome projects have revealed an astonishing diversity of transposable genetic elements, implying the existence of novel element families yet to be discovered from diverse life forms. Concurrently, s...

    Authors: Maria I Pajunen, Tiina S Rasila, Lotta J Happonen, Arja Lamberg, Saija Haapa-Paananen, Saija Kiljunen and Harri Savilahti

    Citation: Mobile DNA 2010 1:24

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  12. Content type: Research

    Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to...

    Authors: Nicholas A Wallace, Victoria P Belancio, Zach Faber and Prescott Deininger

    Citation: Mobile DNA 2010 1:22

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  13. Content type: Meeting Report

    An international conference on mobile DNA was held 24-28 April 2010 in Montreal, Canada. Sponsored by the American Society for Microbiology, the conference's goal was to bring together researchers from around ...

    Authors: George Chaconas, Nancy Craig, M Joan Curcio, Prescott Deininger, Cedric Feschotte, Henry Levin, Phoebe A Rice and Daniel F Voytas

    Citation: Mobile DNA 2010 1:20

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  14. Content type: Research

    Retrotransposons are abundant components of plant genomes, and although some plant retrotransposons have been used as insertional mutagens, these mobile genetic elements have not been widely exploited for plan...

    Authors: Yi Hou, Jyothi Rajagopal, Phillip A Irwin and Daniel F Voytas

    Citation: Mobile DNA 2010 1:19

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  15. Content type: Research

    Tight regulation of transposition activity is essential to limit damage transposons may cause by generating potentially lethal DNA rearrangements. Assembly of a bona fide protein-DNA complex, the transpososome...

    Authors: Philippe Rousseau, Catherine Tardin, Nathalie Tolou, Laurence Salomé and Mick Chandler

    Citation: Mobile DNA 2010 1:16

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  16. Content type: Short Report

    The yeast retrotransposon Ty3 forms stable virus-like particles. Gag3, the major structural protein, is composed of capsid, spacer and nucleocapsid domains. The capsid domain of Gag3 was previously modeled as ...

    Authors: Min Zhang, Liza SZ Larsen, Becky Irwin, Virginia Bilanchone and Suzanne Sandmeyer

    Citation: Mobile DNA 2010 1:14

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  17. Content type: Research

    The ends of chromosomes, termed telomeres consist of repetitive DNA. The telomeric sequences shorten with cell division and, when telomeres are critically abbreviated, cells stop proliferating. However, in can...

    Authors: Kazutoshi Yoshitake, Hideyuki Aoyagi and Haruhiko Fujiwara

    Citation: Mobile DNA 2010 1:13

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  18. Content type: Research

    Rotifers of the class Bdelloidea are microscopic freshwater invertebrates best known for: their capacity for anhydrobiosis; the lack of males and meiosis; and for the ability to capture genes from other non-me...

    Authors: Eugene A Gladyshev and Irina R Arkhipova

    Citation: Mobile DNA 2010 1:12

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  19. Content type: Research

    L1s are one of the most successful autonomous mobile elements in primate genomes. These elements comprise as much as 17% of primate genomes with the majority of insertions occurring via target primed reverse t...

    Authors: Thomas J Meyer, Deepa Srikanta, Erin M Conlin and Mark A Batzer

    Citation: Mobile DNA 2010 1:7

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  20. Content type: Research

    How new forms arise in nature has engaged evolutionary biologists since Darwin's seminal treatise on the origin of species. Transposable elements (TEs) may be among the most important internal sources for intr...

    Authors: Alexander Belyayev, Ruslan Kalendar, Leonid Brodsky, Eviatar Nevo, Alan H Schulman and Olga Raskina

    Citation: Mobile DNA 2010 1:6

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  21. Content type: Research

    PIF/Harbinger is the most recently discovered DNA transposon superfamily and is now known to populate genomes from fungi to plants to animals. Mobilization of superfamily members requires two separate element-enc...

    Authors: C Nathan Hancock, Feng Zhang and Susan R Wessler

    Citation: Mobile DNA 2010 1:5

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  22. Content type: Review

    Scientific history has had a profound effect on the theories of evolution. At the beginning of the 21st century, molecular cell biology has revealed a dense structure of information-processing networks that us...

    Authors: James A Shapiro

    Citation: Mobile DNA 2010 1:4

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