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  • Correction
  • Open Access

Correction to: The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation

  • 1,
  • 1,
  • 2,
  • 3,
  • 3, 4,
  • 2 and
  • 1Email author
Mobile DNA20189:16

https://doi.org/10.1186/s13100-018-0121-8

  • Published:

The original article was published in Mobile DNA 2018 9:11

Correction

The original article [1] contains an omission in the Methods. The authors would like to note that the paragraph constituting the L1 promoter assay should read as the following:

L1 promoter assay

HEK-293T cells were transfected with the L1 promoter luciferase reporter plasmid (L1RP-luc) together with empty vector (pcDNA6mycHis) or SAMHD1 expressing vector using calcium phosphate. The reporter plasmid L1RP-luc and the L1 promoter activity assay have been described previously [2]. Two days posttransfection, cells were lysed with Cell Culture Lysis 5× reagent (Promega) and luciferase activity was quantified using commercially available components (Promega).

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany
(2)
pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
(3)
Center for Drug Discovery, Department of Pediatrics, Emory Center for AIDS Research, Emory University, Children’s Healthcare of Atlanta, Atlanta, GA 30322, USA
(4)
College of Pharmacy, Kyung-Hee University, Seoul, South Korea

References

  1. Herrmann A, et al. The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. Mob DNA. 2018;9:11.View ArticlePubMedPubMed CentralGoogle Scholar
  2. Yu F, Zingler N, Schumann G, Strätling WH. Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription. Nucleic Acids Res. 2001;29:4493–501.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s). 2018

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