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  1. Retrotransposons have been implicated as causes of Mendelian disease, but their role in autism spectrum disorder (ASD) has not been systematically defined, because they are only called with adequate sensitivit...

    Authors: Rebeca Borges-Monroy, Chong Chu, Caroline Dias, Jaejoon Choi, Soohyun Lee, Yue Gao, Taehwan Shin, Peter J. Park, Christopher A. Walsh and Eunjung Alice Lee
    Citation: Mobile DNA 2021 12:28
  2. The majority of structural variation in genomes is caused by insertions of transposable elements (TEs). In mammalian genomes, the main TE fraction is made up of autonomous and non-autonomous non-LTR retrotrans...

    Authors: Malte Petersen, Sven Winter, Raphael Coimbra, Menno J. de Jong, Vladimir V. Kapitonov and Maria A. Nilsson
    Citation: Mobile DNA 2021 12:27
  3. LINE-1 (Long Interspersed Nuclear Elements, L1) retrotransposons are the only autonomously active transposable elements in the human genome. The evolution of L1 retrotransposition rates and its implications fo...

    Authors: Sawsan Sami Wehbi and Heinrich zu Dohna
    Citation: Mobile DNA 2021 12:26
  4. Tn5253, a composite Integrative Conjugative Element (ICE) of Streptococcus pneumoniae carrying tet(M) and cat resistance determinants, was found to (i) integrate at specific 83-bp integration site (attB), (ii) pr...

    Authors: Francesco Santoro, Valeria Fox, Alessandra Romeo, Elisa Lazzeri, Gianni Pozzi and Francesco Iannelli
    Citation: Mobile DNA 2021 12:25
  5. With the expansion of high throughput sequencing, we now have access to a larger number of genome-wide studies analyzing the Transposable elements (TEs) composition in a wide variety of organisms. However, gen...

    Authors: Jonathan Filée, Sarah Farhat, Dominique Higuet, Laure Teysset, Dominique Marie, Camille Thomas-Bulle, Stephane Hourdez, Didier Jollivet and Eric Bonnivard
    Citation: Mobile DNA 2021 12:24
  6. The submandibular gland (SG) is a relatively simple organ formed by three cell types: acinar, myoepithelial, and an intricate network of duct-forming epithelial cells, that together fulfills several physiologi...

    Authors: Braulio Valdebenito-Maturana, Francisca Torres, Mónica Carrasco and Juan Carlos Tapia
    Citation: Mobile DNA 2021 12:23
  7. Transposable elements (TEs) significantly contribute to shaping the diversity of the human genome, and lines of evidence suggest TEs as one of driving forces of human brain evolution. Existing computational ap...

    Authors: Yilan Wang, Boxun Zhao, Jaejoon Choi and Eunjung Alice Lee
    Citation: Mobile DNA 2021 12:22
  8. The autonomous retroelement Long Interspersed Element-1 (LINE-1) mobilizes though a copy and paste mechanism using an RNA intermediate (retrotransposition). Throughout human evolution, around 500,000 LINE-1 se...

    Authors: Erica M. Briggs, Paolo Mita, Xiaoji Sun, Susan Ha, Nikita Vasilyev, Zev R. Leopold, Evgeny Nudler, Jef D. Boeke and Susan K. Logan
    Citation: Mobile DNA 2021 12:21
  9. Toll-like receptors (TLRs) play important roles in building innate immune and inducing adaptive immune responses. Associations of the TLR genes polymorphisms with disease susceptibility, which are the basis of mo...

    Authors: XiaoYan Wang, Zixuan Chen, Eduard Murani, Enrico D’Alessandro, Yalong An, Cai Chen, Kui Li, Grazia Galeano, Klaus Wimmers and Chengyi Song
    Citation: Mobile DNA 2021 12:20
  10. Molecular markers based on retrotransposon insertion polymorphisms (RIPs) have been developed and are widely used in plants and animals. Short interspersed nuclear elements (SINEs) exert wide impacts on gene a...

    Authors: Cai Chen, Enrico D’Alessandro, Eduard Murani, Yao Zheng, Domenico Giosa, Naisu Yang, Xiaoyan Wang, Bo Gao, Kui Li, Klaus Wimmers and Chengyi Song
    Citation: Mobile DNA 2021 12:17
  11. Transposable elements (TEs) play powerful and varied evolutionary and functional roles, and are widespread in most eukaryotic genomes. Research into their unique biology has driven the creation of a large coll...

    Authors: Tyler A. Elliott, Tony Heitkam, Robert Hubley, Hadi Quesneville, Alexander Suh and Travis J. Wheeler
    Citation: Mobile DNA 2021 12:16
  12. Transposable elements (TEs) are repetitive sequences of viral origin that compose almost half of the human genome. These elements are tightly controlled within cells, and if activated, they can cause changes i...

    Authors: Mahboubeh R. Rostami and Martina Bradic
    Citation: Mobile DNA 2021 12:14
  13. Transposons are mobile genetic elements that colonize genomes and drive their plasticity in all organisms. DNA transposon-encoded transposases bind to the ends of their cognate transposons and catalyze their m...

    Authors: Marc Guérineau, Luiza Bessa, Séverine Moriau, Ewen Lescop, François Bontems, Nathalie Mathy, Eric Guittet, Julien Bischerour, Mireille Bétermier and Nelly Morellet
    Citation: Mobile DNA 2021 12:12
  14. SINEs comprise a significant part of animal genomes and are used to study the evolution of diverse taxa. Despite significant advances in SINE studies in vertebrates and higher eukaryotes in general, their own ...

    Authors: Nikita S. Vassetzky, Sergei A. Kosushkin, Vitaly I. Korchagin and Alexey P. Ryskov
    Citation: Mobile DNA 2021 12:10
  15. Group II introns are mobile retroelements, capable of invading new sites in DNA. They are self-splicing ribozymes that complex with an intron-encoded protein to form a ribonucleoprotein that targets DNA after ...

    Authors: Justin M. Waldern, Dorie Smith, Carol Lyn Piazza, E. Jake Bailey, Nicholas J. Schiraldi, Reza Nemati, Dan Fabris, Marlene Belfort and Olga Novikova
    Citation: Mobile DNA 2021 12:9
  16. Plant genomes can respond rapidly to environmental changes and transposable elements (TEs) arise as important drivers contributing to genome dynamics. Although some elements were reported to be induced by vari...

    Authors: Guillaume Wos, Rimjhim Roy Choudhury, Filip Kolář and Christian Parisod
    Citation: Mobile DNA 2021 12:7
  17. Transposable elements (TEs) are enriched in cytosine methylation, preventing their mobility within the genome. We previously identified a genome-wide repertoire of candidate intracisternal A particle (IAP) TEs...

    Authors: Jessica L. Elmer, Amir D. Hay, Noah J. Kessler, Tessa M. Bertozzi, Eve A. C. Ainscough and Anne C. Ferguson-Smith
    Citation: Mobile DNA 2021 12:6
  18. Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to “copy-and-paste” itself into new loci of the host genome through a process called retrotransposition. The LINE-1 bicistronic mRNA code...

    Authors: Erica M. Briggs, Wilson McKerrow, Paolo Mita, Jef D. Boeke, Susan K. Logan and David Fenyö
    Citation: Mobile DNA 2021 12:5
  19. Transposable elements (TEs) are major components of all vertebrate genomes that can cause deleterious insertions and genomic instability. However, depending on the specific genomic context of their insertion s...

    Authors: Ema Etchegaray, Magali Naville, Jean-Nicolas Volff and Zofia Haftek-Terreau
    Citation: Mobile DNA 2021 12:1
  20. Retroelements (REs) occupy a significant part of all eukaryotic genomes including humans. The majority of retroelements in the human genome are inactive and unable to retrotranspose. Dozens of active copies ar...

    Authors: Alexander Y. Komkov, Shamil Z. Urazbakhtin, Maria V. Saliutina, Ekaterina A. Komech, Yuri A. Shelygin, Gaiaz A. Nugmanov, Vitaliy P. Shubin, Anastasia O. Smirnova, Mikhail Y. Bobrov, Alexey S. Tsukanov, Anastasia V. Snezhkina, Anna V. Kudryavtseva, Yuri B. Lebedev and Ilgar Z. Mamedov
    Citation: Mobile DNA 2020 11:33
  21. A family of Tc1/mariner transposons with a characteristic DD38E triad of catalytic amino acid residues, named Intruder (IT), was previously discovered in sturgeon genomes, but their evolutionary landscapes remain...

    Authors: Bo Gao, Wencheng Zong, Csaba Miskey, Numan Ullah, Mohamed Diaby, Cai Chen, Xiaoyan Wang, Zoltán Ivics and Chengyi Song
    Citation: Mobile DNA 2020 11:32
  22. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin and Robert Belshaw
    Citation: Mobile DNA 2020 11:31

    The original article was published in Mobile DNA 2020 11:9

  23. Mobile genetic elements are found in genomes throughout the microbial world, mediating genome plasticity and important prokaryotic phenotypes. Even the cell wall-less mycoplasmas, which are known to harbour a ...

    Authors: Birgit Henrich, Stephanie Hammerlage, Sebastian Scharf, Diana Haberhausen, Ursula Fürnkranz, Karl Köhrer, Lena Peitzmann, Pier Luigi Fiori, Joachim Spergser, Klaus Pfeffer and Alexander T. Dilthey
    Citation: Mobile DNA 2020 11:30
  24. Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of mammalian germline cells. A large proportion of ERVs lose their open reading frames (ORFs), while others retain them and become e...

    Authors: Mahoko Takahashi Ueda, Kirill Kryukov, Satomi Mitsuhashi, Hiroaki Mitsuhashi, Tadashi Imanishi and So Nakagawa
    Citation: Mobile DNA 2020 11:29
  25. Tc1/mariner and Zator, as two superfamilies of IS630-Tc1-mariner (ITm) group, have been well-defined. However, the molecular evolution and domestication of pogo transposons, once designated as an important family...

    Authors: Bo Gao, Yali Wang, Mohamed Diaby, Wencheng Zong, Dan Shen, Saisai Wang, Cai Chen, Xiaoyan Wang and Chengyi Song
    Citation: Mobile DNA 2020 11:25
  26. The target capture protein MuB is responsible for the high efficiency of phage Mu transposition within the E. coli genome. However, some targets are off-limits, such as regions immediately outside the Mu ends (ci...

    Authors: David M. Walker and Rasika M. Harshey
    Citation: Mobile DNA 2020 11:26
  27. Insertion sequences (IS) are ubiquitous transposable elements with a very simple organization: two inverted repeats flanking a transposase coding gene. IS982 is one of 26 insertion sequence families known so far....

    Authors: Nancy Fayad, Mireille Kallassy Awad and Jacques Mahillon
    Citation: Mobile DNA 2020 11:24
  28. Drosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable elements (TEs) is not an exception. Drosophila has contributed signi...

    Authors: Vincent Mérel, Matthieu Boulesteix, Marie Fablet and Cristina Vieira
    Citation: Mobile DNA 2020 11:23
  29. Endogenous retroviruses (ERVs) are the remnants of retroviral infections which can elicit prolonged genomic and immunological stress on their host organism. In chickens, endogenous Avian Leukosis Virus subgrou...

    Authors: Andrew S. Mason, Ashlee R. Lund, Paul M. Hocking, Janet E. Fulton and David W. Burt
    Citation: Mobile DNA 2020 11:22
  30. Tc1/mariner transposons are widespread DNA transposable elements (TEs) that have made important contributions to the evolution of host genomic complexity in metazoans. However, the evolution and diversity of the

    Authors: Mathilde Dupeyron, Tobias Baril, Chris Bass and Alexander Hayward
    Citation: Mobile DNA 2020 11:21
  31. Extensive and complex links exist between transposable elements (TEs) and satellite DNA (satDNA), which are the two largest fractions of eukaryotic genome. These relationships have a crucial effect on genome s...

    Authors: Alexander Belyayev, Jiřina Josefiová, Michaela Jandová, Václav Mahelka, Karol Krak and Bohumil Mandák
    Citation: Mobile DNA 2020 11:20
  32. The extreme genome reduction and physiological simplicity of some microsporidia has been attributed to their intracellular, obligate parasitic lifestyle. Although not all microsporidian genomes are small (size...

    Authors: Nathalia Rammé Medeiros de Albuquerque, Dieter Ebert and Karen Luisa Haag
    Citation: Mobile DNA 2020 11:19
  33. V(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The RAG1 and RAG2 genes are thought to have evolved from a RAGL (RAG-like) transposon c...

    Authors: Eliza C. Martin, Célia Vicari, Louis Tsakou-Ngouafo, Pierre Pontarotti, Andrei J. Petrescu and David G. Schatz
    Citation: Mobile DNA 2020 11:17
  34. Nearly half the human genome consists of repeat elements, most of which are retrotransposons, and many of which play important biological roles. However repeat elements pose several unique challenges to curren...

    Authors: Jason D. Fernandes, Armando Zamudio-Hurtado, Hiram Clawson, W. James Kent, David Haussler, Sofie R. Salama and Maximilian Haeussler
    Citation: Mobile DNA 2020 11:13

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