Obituary
Mobile DNA 2016 7:13
Published on: 26 July 2016
Articles
- Sort by
-
-
Research
Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome
Around 40 million years ago DNA transposons began accumulating in an ancestor of bats in the family Vespertilionidae. Since that time, Class II transposons have been continuously reinvading and accumulating in...
Mobile DNA 2016 7:12
Published on: 22 July 2016
-
Research
Distribution of the DNA transposon family, Pokey in the Daphnia pulex species complex
The Pokey family of DNA transposons consists of two putatively autonomous groups, PokeyA and PokeyB, and two groups of Miniature Inverted-repeat Transposable Elements (MITEs), mPok1 and mPok2. This TE family is u...
Mobile DNA 2016 7:11
Published on: 17 June 2016
-
Review
Roles for retrotransposon insertions in human disease
Over evolutionary time, the dynamic nature of a genome is driven, in part, by the activity of transposable elements (TE) such as retrotransposons. On a shorter time scale it has been established that new TE in...
Mobile DNA 2016 7:9
Published on: 6 May 2016
-
Research
Genomic analysis of mouse VL30 retrotransposons
Retrotransposons are mobile elements that have a high impact on shaping the mammalian genomes. Since the availability of whole genomes, genomic analyses have provided novel insights into retrotransposon biolog...
Mobile DNA 2016 7:10
Published on: 6 May 2016
-
Research
The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations
Approximately 17 % of the human genome is comprised of the Long INterspersed Element-1 (LINE-1 or L1) retrotransposon, the only currently active autonomous family of retroelements. Though L1 elements have helped ...
Mobile DNA 2016 7:8
Published on: 19 April 2016
-
Methodology
Alu SINE analyses of 3,000-year-old human skeletal remains: a pilot study
As Short Interspersed Elements (SINEs), human-specific Alu elements can be used for population genetic studies. Very recent inserts are polymorphic within and between human populations. In a sample of 30 elements...
Mobile DNA 2016 7:7
Published on: 18 April 2016
-
Research
Active recombinant Tol2 transposase for gene transfer and gene discovery applications
The revolutionary concept of “jumping genes” was conceived by McClintock in the late 1940s while studying the Activator/Dissociation (Ac/Ds) system in maize. Transposable elements (TEs) represent the most abundan...
Mobile DNA 2016 7:6
Published on: 31 March 2016
-
Research
The contribution of transposable elements to size variations between four teleost genomes
Teleosts are unique among vertebrates, with a wide range of haploid genome sizes in very close lineages, varying from less than 400 mega base pairs (Mb) for pufferfish to over 3000 Mb for salmon. The cause of ...
Mobile DNA 2016 7:4
Published on: 9 February 2016
-
Erratum
Mobile DNA 2016 7:5
Published on: 9 February 2016
The original article was published in Mobile DNA 2015 6:22
-
Software
Genome ARTIST: a robust, high-accuracy aligner tool for mapping transposon insertions and self-insertions
A critical topic of insertional mutagenesis experiments performed on model organisms is mapping the hits of artificial transposons (ATs) at nucleotide level accuracy. Mapping errors may occur when sequencing a...
Mobile DNA 2016 7:3
Published on: 5 February 2016
-
Research
Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha
Transposable elements are a major player contributing to genetic variation and shaping genome evolution. Multiple independent transposon domestication events have occurred in ciliates, recruiting transposases ...
Mobile DNA 2016 7:2
Published on: 25 January 2016
-
Research
Isolation and characterization of putative functional long terminal repeat retrotransposons in the Pyrus genome
Long terminal repeat (LTR)-retrotransposons constitute 42.4 % of the genome of the ‘Suli’ pear (Pyrus pyrifolia white pear group), implying that retrotransposons have played important roles in Pyrus evolution. Th...
Mobile DNA 2016 7:1
Published on: 15 January 2016
-
Review
Transposable element detection from whole genome sequence data
The number of software tools available for detecting transposable element insertions from whole genome sequence data has been increasing steadily throughout the last ~5 years. Some of these methods have unique...
Mobile DNA 2015 6:24
Published on: 29 December 2015
-
Research
The making of a genomic parasite - the Mothra family sheds light on the evolution of Helitrons in plants
Helitrons are Class II transposons which are highly abundant in almost all eukaryotes. However, most Helitrons lack protein coding sequence. These non-autonomous elements are thought to hijack recombinase/heli...
Mobile DNA 2015 6:23
Published on: 17 December 2015
-
Research
Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon
A large number of Saccharomyces cerevisiae cellular factors modulate the movement of the retrovirus-like transposon Ty1. Surprisingly, a significant number of chromosomal genes required for Ty1 transposition enco...
Mobile DNA 2015 6:22
Published on: 8 December 2015
The Erratum to this article has been published in Mobile DNA 2016 7:5
-
Research
Transposable element polymorphisms recapitulate human evolution
The human genome contains several active families of transposable elements (TE): Alu, L1 and SVA. Germline transposition of these elements can lead to polymorphic TE (polyTE) loci that differ between individua...
Mobile DNA 2015 6:21
Published on: 16 November 2015
-
Meeting Report
First international workshop on human endogenous retroviruses and diseases, HERVs & disease 2015
The First International Scientific Conference on Human Endogenous Retroviruses (HERVs) and Disease, Lyon-France, May 26-27th 2015, brought together scientific and medical specialists from around the world investi...
Mobile DNA 2015 6:20
Published on: 15 October 2015
-
Research
A long terminal repeat retrotransposon of Schizosaccharomyces japonicus integrates upstream of RNA pol III transcribed genes
Transposable elements (TEs) are common constituents of centromeres. However, it is not known what causes this relationship. Schizosaccharomyces japonicus contains 10 families of Long Terminal Repeat (LTR)-retrotr...
Mobile DNA 2015 6:19
Published on: 9 October 2015
-
Research
Identification and characterization of a minisatellite contained within a novel miniature inverted-repeat transposable element (MITE) of Porphyromonas gingivalis
Repetitive regions of DNA and transposable elements have been found to constitute large percentages of eukaryotic and prokaryotic genomes. Such elements are known to be involved in transcriptional regulation, ...
Mobile DNA 2015 6:18
Published on: 6 October 2015
-
Review
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family
Tandem C2H2-type zinc finger proteins (ZFPs) constitute the largest transcription factor family in animals. Tandem-ZFPs bind DNA in a sequence-specific manner through arrays of multiple zinc finger domains tha...
Mobile DNA 2015 6:17
Published on: 2 October 2015
-
Research
Comparative paleovirological analysis of crustaceans identifies multiple widespread viral groups
The discovery of many fragments of viral genomes integrated in the genome of their eukaryotic host (endogenous viral elements; EVEs) has recently opened new avenues to further our understanding of viral evolut...
Mobile DNA 2015 6:16
Published on: 16 September 2015
-
Research
Precise repair of mPing excision sites is facilitated by target site duplication derived microhomology
A key difference between the Tourist and Stowaway families of miniature inverted repeat transposable elements (MITEs) is the manner in which their excision alters the genome. Upon excision, Stowaway-like MITEs an...
Mobile DNA 2015 6:15
Published on: 7 September 2015
-
Research
A host factor supports retrotransposition of the TRE5-A population in Dictyostelium cells by suppressing an Argonaute protein
In the compact and haploid genome of Dictyostelium discoideum control of transposon activity is of particular importance to maintain viability. The non-long terminal repeat retrotransposon TRE5-A amplifies contin...
Mobile DNA 2015 6:14
Published on: 3 September 2015
-
Commentary
A call for benchmarking transposable element annotation methods
DNA derived from transposable elements (TEs) constitutes large parts of the genomes of complex eukaryotes, with major impacts not only on genomic research but also on how organisms evolve and function. Althoug...
Mobile DNA 2015 6:13
Published on: 4 August 2015
