Editors' Picks

Lamivudine modulates the expression of neurological impairment-related genes and LINE-1 retrotransposons in brain tissues of a Down syndrome mouse model. [Front Aging Neurosci. 2024] PubMed

Evolution of Einkorn wheat centromeres is driven by the mutualistic interplay of two LTR retrotransposons. [Mob DNA. 2024] PubMed

Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons. [Nat Commun. 2024] PubMed

ZNF91 is an endogenous repressor of the molecular phenotype associated with X-linked dystonia-parkinsonism (XDP). [Proc Natl Acad Sci U S A. 2024] PubMed

Discovery of numerous novel Helitron-like elements in eukaryote genomes using HELIANO. [Nucleic Acids Res. 2024] PubMed

Transposition with Tn3-family elements occurs through interaction with the host β-sliding clamp processivity factor. [Nucleic Acids Res. 2024] PubMed

Two HUSH complexes connect a direct LINE to innate immunity. [Mol Cell. 2024] PubMed

Mobile element insertions affect human pigmentation and skin cancer risk. [Nat Genet. 2024] PubMed

Identification of mobile genetic elements with geNomad. [Nat Biotechnol. 2024] PubMed

A telomere-to-telomere cotton genome assembly reveals centromere evolution and a Mutator transposon-linked module regulating embryo development. [Nat Genet. 2024] PubMed

The genomes of all lungfish inform on genome expansion and tetrapod evolution. [Nature 2024] PubMed

H-NS is a bacterial transposon capture protein. [Nat Commun. 2024] PubMed

DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor. [Nat Commun. 2024] PubMed

LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response. [EMBO J. 2024] PubMed

HiTE: a fast and accurate dynamic boundary adjustment approach for full-length transposable element detection and annotation. [Nat Commun. 2024] PubMed

Directed evolution of hyperactive integrases for site specific insertion of transgenes. [Nucleic Acids Res. 2024] PubMed

Structure and sequence at an RNA template 5' end influence insertion of transgenes by an R2 retrotransposon protein. [RNA. 2024] PubMed

LINE1 mediates long-range DNA interactions. [Nat Genet. 2024] PubMed  

TEENA: an integrated web server for transposable element enrichment analysis in various model and non-model organisms. [Nucleic Acids Res. 2024] PubMed  

Novel Alu insertion in the ZEB2 gene causing Mowat-Wilson syndrome. [Am J Med Genet A. 2024] PubMed  

Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes. [Nat Commun. 2024] PubMed  

Copy number variation introduced by a massive mobile element facilitates global thermal adaptation in a fungal wheat pathogen. [Nat Commun. 2024] PubMed  

All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposons. [Cell. 2024] PubMed 

Heterologous survey of 130 DNA transposons in human cells highlights their functional divergence and expands the genome engineering toolbox. [Cell. 2024] PubMed

Antagonistic conflict between transposon-encoded introns and guide RNAs. [Science. 2024] PubMed

Competition between two HUSH complexes orchestrates the immune response to retroelement invasion. [Mol Cell. 2024] PubMed  

Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer. [Sci Adv. 2024] PubMed  

Transposase-assisted target-site integration for efficient plant genome engineering. [Nature. 2024] PubMed  

A sequence of SVA retrotransposon insertions in ASIP shaped human pigmentation. [Nat Genet. 2024] PubMed  

Transposon-derived introns as an element shaping the structure of eukaryotic genomes. [Mob DNA. 2024] PubMed  

LINE1 and its host: one cell's junk is another cell's treasure. [EMBO J. 2024] PubMed  

Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease. [Nat Struct Mol Biol. 2024] PubMed

Heterologous survey of 130 DNA transposons in human cells highlights their functional divergence and expands the genome engineering toolbox [Cell. 2024] PubMed

Variable patterns of retrotransposition in different HeLa strains provide mechanistic insights into SINE RNA mobilization processes.[Nucleic Acids Res. 2024] PubMed

LINE-1 transcription activates long-range gene expression. [Nat Genet. 2024] PubMed

Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model. [Nat Commun. 2024] PubMed

Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. [Mol Cell. 2024] PubMed

Internal initiation of reverse transcription in a Penelope-like retrotransposon. [Mob DNA. 2024] PubMed

The transcription factor PAX5 activates human LINE1 retrotransposons to induce cellular senescence. [EMBO Rep. 2024] PubMed

Mapping the structural landscape of the yeast Ty3 retrotransposon RNA genome. [Nucleic Acids Res. 2024] PubMed

Going viral: The role of mobile genetic elements in bacterial immunity. [Cell Host Microbe. 2024] PubMed

Direct transposition of native DNA for sensitive multimodal single-molecule sequencing. [Nat Genet. 2024] PubMed

TnpB homologues exapted from transposons are RNA-guided transcription factors. [Nature. 2024] PubMed

The R2R3 MYB Ruby1 is activated by two cold responsive ethylene response factors, via the retrotransposon in its promoter, to positively regulate anthocyanin biosynthesis in citrus. [Plant J. 2024] PubMed

Subcellular location of L1 retrotransposon-encoded ORF1p, reverse transcription products, and DNA sensors in lupus granulocytes.[Mob DNA. 2024] PubMed

Structural mechanism of bridge RNA-guided recombination. [Nature. 2024] PubMed

Bridge RNAs direct programmable recombination of target and donor DNA. [Nature. 2024] PubMed

Molecular basis for transposase activation by a dedicated AAA+ ATPase. [Nature. 2024] PubMed

Long-read sequencing improves the genetic diagnosis of retinitis pigmentosa by identifying an Alu retrotransposon insertion in the EYS gene. [Mob DNA. 2024] PubMed

Teaching transposon classification as a means to crowd source the curation of repeat annotation - a tardigrade perspective. [Mob DNA. 2024] PubMed

Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease. [Nat Commun. 2024] PubMed

Transposable elements impact the population divergence of rice blast fungus Magnaporthe oryzae. [mBio. 2024] PubMed

Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse. [Mob DNA. 2024] PubMed

Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary. [Genome Res. 2024] PubMed

Conserved and divergent DNA recognition specificities and functions of R2 retrotransposon N-terminal domains. [Cell Rep. 2024] PubMed

Transposon DNA sequences facilitate the tissue-specific gene transfer of circulating tumor DNA between human cells. [Nucleic Acids Res. 2024] PubMed

Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions. [Nat Commun. 2024] PubMed

LINE-1 retrotransposons contribute to mouse PV interneuron development. [Nat Neurosci. 2024] PubMed

A metagenomics pipeline reveals insertion sequence-driven evolution of the microbiota. [Cell Host Microbe. 2024] PubMed

Genomes of historical specimens reveal multiple invasions of LTR retrotransposons in Drosophila melanogaster during the 19th century. [Proc Natl Acad Sci U S A. 2024] PubMed

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence. [Elife. 2024] PubMed

Human brain small extracellular vesicles contain selectively packaged, full-length mRNA. [Cell Rep. 2024] PubMed

Earl Grey: a fully automated user-friendly transposable element annotation and analysis pipeline. [Mol Biol Evol. 2024] PubMed

The impact of differential transposition activities of autonomous and non-autonomous hAT transposable elements on genome architecture and gene expression in Caenorhabditis inopinata. [Genetics. 2024] PubMed

Natural and Engineered Guide RNA-directed Transposition with CRISPR-Associated Tn7-like Transposons. [Annu Rev Biochem. 2024] PubMed

SAFB restricts contact domain boundaries associated with L1 chimeric transcription. [Mol Cell. 2024] PubMed

Multiple horizontal transfer events of a DNA transposon into turtles, fishes, and a frog. [Mob DNA. 2024] PubMed

The evolution of transposable elements in Brachypodium distachyon is governed by purifying selection, while neutral and adaptive processes play a minor role. [Elife. 2024] PubMed

Adaptive expansion of ERVK solo-LTRs is associated with Passeriformes speciation events. [Nat Commun. 2024] PubMed

Jump-starting life: balancing transposable element co-option and genome integrity in the developing mammalian embryo. [EMBO Rep. 2024] PubMed

Look4LTRs: a Long terminal repeat retrotransposon detection tool capable of cross species studies and discovering recently nested repeats. [Mob DNA. 2024] PubMed

Comprehensive profiling of L1 retrotransposons in mouse. [Nucleic Acids Res. 2024] PubMed

Transposable elements regulate thymus development and function. [Elife. 2024] PubMed

New genes helped acorn barnacles adapt to a sessile lifestyle. [Nat Genet. 2024] PubMed

HERV-W upregulation expression in bipolar disorder and schizophrenia: unraveling potential links to systemic immune/inflammation status. [Retrovirology. 2024] PubMed

The Role of Retrotransposons and Endogenous Retroviruses in Age-Dependent Neurodegenerative Disorders. [Annu Rev Neurosci. 2024] PubMed

Overlapping Streptococcus pyogenes and Streptococcus dysgalactiae subspecies equisimilis household transmission and mobile genetic element exchange. [Nat Commun. 2024] PubMed

Helitrons: genomic parasites that generate developmental novelties. [Trends Genet. 2024]  PubMed

Single-cell analysis of isoform switching and transposable element expression during preimplantation embryonic development. [PLoS Biol. 2024] PubMed

Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery. [Proc Natl Acad Sci U S A. 2024] PubMed

Evolution of a restriction factor by domestication of a yeast retrotransposon. [Mol Biol Evol. 2024] PubMed

ProTInSeq: transposon insertion tracking by ultra-deep DNA sequencing to identify translated large and small ORFs. [Nat Commun. 2024] PubMed 

GWAS reveals determinants of mobilization rate and dynamics of an active endogenous retrovirus of cattle. [Nat Commun. 2024] PubMed 

Rapid dissemination of host metabolism-manipulating genes via integrative and conjugative elements. [Proc Natl Acad Sci U S A. 2024] PubMed 

Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon. [PLoS Genet. 2024] PubMed 

A transposon insertion in the promoter of OsUBC12 enhances cold tolerance during japonica rice germination. [Nat Commun. 2024] PubMed 

How transposable elements are spliced out. [Nat Genet. 2024] PubMed 

Genome-wide repeat landscapes in cancer and cell-free DNA. [Sci Transl Med. 2024] PubMed 

Distinct and overlapping RNA determinants for binding and target-primed reverse transcription by Bombyx mori R2 retrotransposon protein. [Nucleic Acids Res. 2024] PubMed 

Morc1 reestablishes H3K9me3 heterochromatin on piRNA-targeted transposons in gonocytes. [Proc Natl Acad Sci U S A. 2024] PubMed 

Conserved non-coding elements evolve around the same genes throughout Metazoan evolution. [Genome Biol Evol. 2024] PubMed 

A retrotransposon for site-specific gene transfer. [Nat Biotechnol. 2024] PubMed 

Harnessing eukaryotic retroelement proteins for transgene insertion into human safe-harbor loci. [Nat Biotechnol. 2024] PubMed 

The diverse evolutionary histories of domesticated metaviral capsid genes in mammals. [Mol Biol Evol. 2024] PubMed 

Childhood cancer mutagenesis caused by transposase-derived PGBD5. [Sci Adv. 2024] PubMed 

Spoink, a LTR retrotransposon, invaded D. melanogaster populations in the 1990s. [PLoS Genet. 2024] PubMed 

PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. [Cell. 2024] PubMed

Mage transposon: a novel gene delivery system for mammalian cells. [Nucleic Acids Res. 2024] PubMed 

Towards targeting transposable elements for cancer therapy. [Nat Rev Cancer. 2024]  PubMed

Wildlife endogenous retroviruses: colonization, consequences, and cooption. [Trends Genet. 2024]  PubMed

Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition. [Cell Rep. 2024] PubMed

Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation. [Cell Rep. 2024] PubMed

Autonomous transposons tune their sequences to ensure somatic suppression. [Nature. 2024]  PubMed

C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. [Mol Cell. 2024]  PubMed

Every repeat is unique: Exploring the genomic impact of human L1 retrotransposons at locus-specific resolution. [Cell Genom. 2024] PubMed

Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.[Cell Genomics, 2024] PubMed

A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression. [Cell. 2024] PubMed

Systematic evaluation of retroviral LTRs as cis-regulatory elements in mouse embryos. [Cell Rep. 2024] PubMed

On the genetic basis of tail-loss evolution in humans and apes. [Nature. 2024] PubMed

The genomic landscape of transposable elements in yeast hybrids is shaped by structural variation and genotype-specific modulation of transposition rate. [Elife. 2024] PubMed

Activation of human endogenous retroviruses and its physiological consequences. [Nat Rev Mol Cell Biol. 2024] PubMed

Genomic profiling of six human somatic histone H1 variants denotes that H1X accumulates at recently incorporated transposable elements. [Nucleic Acids Res. 2024] PubMed

Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1. [Nucleic Acids Res. 2024] PubMed

Evolutionary insights from profiling LINE-1 activity at allelic resolution in a single human genome. [EMBO J. 2024] PubMed

Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites. [Nat Microbiol. 2024] PubMed

Ribosomal profiling of human endogenous retroviruses in healthy tissues. [BMC Genomics. 2024] PubMed

Cancer Immunotherapy: How to Exploit Transposable Elements? [Clin Chem. 2024] PubMed

Retrotransposon renaissance in early embryos. [Trends in Genetics. 2023] PubMed

TE-TSS: an integrated data resource of human and mouse transposable element (TE)-derived transcription start site (TSS). [Nucleic Acids Res. 2024] PubMed

TADB 3.0: an updated database of bacterial toxin-antitoxin loci and associated mobile genetic elements. [Nucleic Acids Res. 2024] PubMed

ICEberg 3.0: functional categorization and analysis of the integrative and conjugative elements in bacteria. [Nucleic Acids Res. 2024] PubMed

HervD Atlas: a curated knowledgebase of associations between human endogenous retroviruses and diseases. [Nucleic Acids Res. 2024] PubMed

Combined analysis of transposable elements and structural variation in maize genomes reveals genome contraction outpaces expansion. [PLoS Genet. 2023] PubMed

LINE-1 mRNA 3' end dynamics shape its biology and retrotransposition potential. [Nucleic Acids Res. 2024] PubMed

Bacterial genome engineering using CRISPR-associated transposases. [Nat Protoc. 2024] PubMed

Keep quiet: the HUSH complex in transcriptional silencing and disease. [Nat Struct Mol Biol. 2024] PubMed

Evolutionary dynamics of the LTR-retrotransposon crapaud in the Podospora anserina species complex and the interaction with repeat-induced point mutations. [Mob DNA. 2024] PubMed

Microbial evolution through horizontal gene transfer by mobile genetic elements. [Microb Biotechnol. 2024] PubMed

Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection. [Proc Natl Acad Sci U S A. 2024] PubMed

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases. [Nat Biotechnol. 2024] PubMed

Transposon removal Reveals Their Adaptive Fitness Contribution. [Genome Biol Evol. 2024] PubMed

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer. [Cell Rep. 2024] PubMed

Machine learning to detect the SINEs of cancer. [Sci Transl Med. 2024] PubMed

Endogenous retroviruses shape pluripotency specification in mouse embryos. [Sci Adv. 2024] PubMed

MBD2 couples DNA methylation to transposable element silencing during male gametogenesis. [Nat Plants. 2024] PubMed

TDP-43 chronic deficiency leads to dysregulation of transposable elements and gene expression by affecting R-loop and 5hmC crosstalk. [Cell Rep. 2024] PubMed

Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer. [Nat Commun. 2024] PubMed

Ancestral genome reconstruction enhances transposable element annotation by identifying degenerate integrants. [Cell Genom. 2024] PubMed

Transposon dynamics in the emerging oilseed crop Thlaspi arvense. [PLoS Genet. 2024] PubMed

Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction. [Cell Rep. 2023] PubMed

LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities. [Genes Dev. 2023] PubMed

Structures, functions, and adaptations of the human LINE-1 ORF2 protein. [Nature. 2023] PubMed

Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker. [Cancer Discov. 2023] PubMed

Long noncoding RNAs emerge from transposon-derived antisense sequences and may contribute to infection stage-specific transposon regulation in a fungal phytopathogen. [Mob DNA. 2023] PubMed

Meeting report: transposable elements at the crossroads of evolution, health and disease 2023. [Mob DNA. 2023] PubMed

New faces of prokaryotic mobile genetic elements: guide RNAs link transposition with host defense mechanisms. [Curr Opin Syst Biol. 2023] PubMed

Transposons contribute to the functional diversification of the head, gut, and ovary transcriptomes across Drosophila natural strains.[Genome Res. 2023] PubMed

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development. [Genome Res. 2023] PubMed

Contribution and therapeutic implications of retroelement insertions in ataxia telangiectasia. [Am J Hum Genet. 2023] PubMed

Schlafen-5 inhibits LINE-1 retrotransposition. [iScience. 2023] PubMed

Mutator transposon insertions within maize genes often provide a novel outward reading promoter. [Genetics. 2023] PubMed

The landscape of human SVA retrotransposons. [Nucleic Acids Res. 2023] PubMed

Transposable elements: McClintock's legacy revisited. [Nat Rev Genet. 2023] PubMed

Transposon accumulation at xenobiotic gene family loci in aphids. [Genome Res. 2023] PubMed

Co-expression of distinct L1 retrotransposon coiled coils can lead to their entanglement. [Mob DNA. 2023] PubMed

Quantifying the arms race between LINE-1 and KRAB-zinc finger genes through TECookbook. [NAR Genom Bioinform. 2023 ] PubMed

Alu elements confer enhancer-promoter specificity.  [Nat Genet. 2023 Sep] PubMed

Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker.  [Cancer Discov. 2023] PubMed

Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment. [Proc Natl Acad Sci U S A. 2023] PubMed

Transposable elements drive the evolution of metazoan zinc finger genes. [Genome Res. 2023] PubMed

Transposable elements as tissue-specific enhancers in cancers of endodermal lineage. [Nat Commun. 2023] PubMed

Young SINEs in pig genomes impact gene regulation, genetic diversity, and complex traits. [Commun Biol. 2023] PubMed

POGZ suppresses 2C transcriptional program and retrotransposable elements. [Cell Rep. 2023] PubMed

Pan cancer characterization of genes whose expression has been associated with LINE-1 antisense promoter activity. [DNA. 202 ] PubMed

Transposable elements in mammalian chromatin organization. [Nat Rev Genet. 2023] PubMed

600+ insect genomes reveal repetitive element dynamics and highlight biodiversity-scale repeat annotation challenges. [Genome Res. 2023] PubMed

The Polycomb repressive complex 2 deposits H3K27me3 and represses transposable elements in a broad range of eukaryotes. [Curr Biol. 2023] PubMed

Alu transposable elements rewire enhancer-promoter network through RNA pairing. [Mol Cell. 2023] PubMed

Dot1l cooperates with Npm1 to repress endogenous retrovirus MERVL in embryonic stem cells.  [Nucleic Acids Res. 2023] PubMed

Transposon-encoded nucleases use guide RNAs to promote their selfish spread. [Nature. 2023 Sep] PubMed

Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries [ Nat Commun. 2023] PubMed

Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector. [Cell. 2023 Aug] PubMed

Crosstalk between RNA m⁶A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells. [Nat Genet. 2023 Aug] PubMed

Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development. [Nat Struct Mol Biol. 2023 Aug] PubMed

LINE-1 regulates cortical development by acting as long non-coding RNAs. [Nat Commun. 2023 Aug] PubMed

Young LINE-1 transposon 5' UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells. [Nat Cell Biol. 2023 Aug] PubMed

Reactivated endogenous retroviruses promote protein aggregate spreading. [Nat Commun. 2023 Aug] PubMed

Single-cell analysis reveals transcriptomic and epigenomic impacts on the maternal-fetal interface following SARS-CoV-2 infection. [ Nat Cell Biol. 2023] PubMed

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development.  [Nucleic Acids Res. 2023 Jul] PubMed

ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.  [PLoS Genet. 2023 Jul ]  PubMed

The DUF3715 domain has a conserved role in RNA-directed transposon silencing.  [RNA. 2023 Jul ] PubMed

Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis. [Nature. 2023 Jul] PubMed

MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties.  [EMBO Rep. 2023 Jul ] PubMed

Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons.  [Nat Commun. 2023 ] PubMed

Reproducible evaluation of transposable element detectors with McClintock 2 guides accurate inference of Ty insertion patterns in yeast.  [Mob DNA. 2023 ] PubMed

Genome skimming with nanopore sequencing precisely determines global and transposon DNA methylation in vertebrates. [Genome Res. 2023 Jul ] PubMed

An interchangeable prion-like domain is required for Ty1 retrotransposition.  [Proc Natl Acad Sci U S A. 2023 ] PubMed

Transposons are important contributors to gene expression variability under selection in rice populations. [2023 Jul ] PubMed

H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function.  [Nat Struct Mol Biol. 2023 ] PubMed

Pangenome analyses reveal impact of transposable elements and ploidy on the evolution of potato species. [Proc Natl Acad Sci U S A. 2023 ] PubMed

Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding. [Nat Commun. 2023 Jul  ] PubMed

Complementary Alu sequences mediate enhancer-promoter selectivity. [Nature. 2023 Jul ] PubMed

Arms race between anti-silencing and RdDM in noncoding regions of transposable elements. [EMBO Rep. 2023 Aug ] PubMed

A host of armor: Prokaryotic immune strategies against mobile genetic elements.[Cell Rep. 2023 Jul ] PubMed

The retrotransposon R2 maintains Drosophila ribosomal DNA repeats. [Proc Natl Acad Sci U S A. 2023 Jun] PubMed

Transposon signatures of allopolyploid genome evolution. [Nat Commun. 2023 Jun] PubMed

Modularity and diversity of target selectors in Tn7 transposons. [Mol Cell. 2023 May] PubMed

Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition. [Mol Cell. 2023 Jun] PubMed

Long-read direct RNA sequencing reveals epigenetic regulation of chimeric gene-transposon transcripts in Arabidopsis thaliana. [Nat Commun. 2023 Jun] PubMed

Reverse transcriptases prime DNA synthesis. [Nucleic Acids Res. 2023 Jun] PubMed

Template-jumping prime editing enables large insertion and exon rewriting in vivo. [Nat Commun. 2023 Jun] PubMed

Co-option of endogenous retroviruses through genetic escape from TRIM28 repression. [Cell Rep. 2023 Jun] PubMed

Transposons contribute to the acquisition of cell type-specific cis-elements in the brain. [Commun Biol. 2023 Jun] PubMed

Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. [Cell. 2023 Jun] PubMed

Genomics of cold adaptations in the Antarctic notothenioid fish radiation. [Nat Commun. 2023 Jun] PubMed

Replitrons: A major group of eukaryotic transposons encoding HUH endonuclease. [Proc Natl Acad Sci U S A. 2023 Jun] PubMed

Retrotransposon LINE-1 bodies in the cytoplasm of piRNA-deficient mouse spermatocytes: Ribonucleoproteins overcoming the integrated stress response. [PLoS Genet. 2023 Jun] PubMed

Genome expansion by a CRISPR trimmer-integrase. [Nature. 2023 Jun] PubMed

SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas. [Cell Host Microbe. 2023 Jun] PubMed

A complete telomere-to-telomere assembly of the maize genome. [Nat Genet. 2023 Jun] PubMed

An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo. [Elife. 2023 Jun] PubMed

Bridging multiple dimensions: roles of transposable elements in higher-order genome regulation. [Curr Opin Genet Dev. 2023 Jun] PubMed

Selective binding of retrotransposons by ZFP352 facilitates the timely dissolution of totipotency network. [Nat Commun. 2023 Jun] PubMed

A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass. [PLoS Biol. 2023 Jun] PubMed

Relaxed targeting rules help PIWI proteins silence transposons. [Nature. 2023 Jun] PubMed

Ribosomal intergenic spacers are filled with transposon remnants. [Genome Biol Evol. 2023 Jun] PubMed

Virus-like transposons cross the species barrier and drive the evolution of genetic incompatibilities. [Science. 2023 Jun] PubMed

The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods. [PLoS Genet. 2023 Jun] PubMed

The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice. [PLoS Genet. 2023 May] PubMed

Endogenous retroviruses and aging. [Nat Aging. 2023 Feb]

Critically short telomeres derepress retrotransposons to promote genome instability in embryonic stem cells. [Cell Discov. 2023 May] PubMed

ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes. [PLoS Genet. 2023 May] PubMed

Expression of L1 retrotransposons in granulocytes from patients with active systemic lupus erythematosus. [Mob DNA. 2023 May] PubMed

Co-transcriptional genome surveillance by HUSH is coupled to termination machinery. [Mol Cell. 2023 Apr 28] PubMed

Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk. [Nat Genet. 2023 May] PubMed

The influence of transposable elements on animal colouration. [Trends Genet. 2023 May] PubMed

Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons and microhomology-mediated recombination. [PLoS Genet. 2023 May] PubMed

Cycles of satellite and transposon evolution in Arabidopsis centromeres. [Nature. 2023 May] PubMed

Host range of strand-biased circularizing integrative elements: a new class of mobile DNA elements nesting in Gammaproteobacteria. [Mob DNA. 2023 May] PubMed

Regulation of human trophoblast gene expression by endogenous retroviruses. [Nat Struct Mol Biol. 2023] PubMed

Major proliferation of transposable elements shaped the genome of the soybean rust pathogen Phakopsora pachyrhizi. [Nat Commun. 2023] PubMed

Cryo-EM structure of the transposon-associated TnpB enzyme. [Nature. 2023] PubMed

TnpB structure reveals minimal functional core of Cas12 nuclease family. [Nature. 2023] PubMed

New tRNA-targeting transposons that hijack phage and vesicles. [Trends Genet. 2023] PubMed

TrEMOLO: accurate transposable element allele frequency estimation using long-read sequencing data combining assembly and mapping-based approaches. [Genome Biol. 2023] PubMed

Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription. [Science. 2023] PubMed

The defense island repertoire of the Escherichia coli pan-genome. [PLoS Genet. 2023] PubMed

Starships are active eukaryotic transposable elements mobilized by a new family of tyrosine recombinases. [Proc Natl Acad Sci U S A. 2023] PubMed

AFM-based force spectroscopy unravels stepwise formation of the DNA transposition complex in the widespread Tn3 family mobile genetic elements. [Nucleic Acids Res. 2023] PubMed

Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species. [Mob DNA. 2023] PubMed

Large-scale invasion of unicellular eukaryotic genomes by integrating DNA viruses. [Proc Natl Acad Sci U S A. 2023] PubMed

Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements. [Nat Genet. 2023] PubMed

A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis. [Nucleic Acids Res. 2023] PubMed

Novel molecular requirements for CRISPR RNA-guided transposition. [Nucleic Acids Res. 2023] PubMed

Repetitive elements in aging and neurodegeneration. [Trends Genet. 2023] PubMed

Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia. [Mol Biol Evol. 2023] PubMed

Expression of retrotransposons contributes to aging in Drosophila. [Genetics. 2023] PubMed

Insights into mammalian TE diversity through the curation of 248 genome assemblies. [Science. 2023] PubMed

Condensation of LINE-1 is critical for retrotransposition. [Elife. 2023] PubMed

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites. [Science. 2023] PubMed

Differentially Expressed Genes Associated with Body Size Changes and Transposable Element Insertions between Caenorhabditis elegans and Its Sister Species, Caenorhabditis inopinata. [Genome Biol Evol. 2023] PubMed

Endogenous retrovirus-derived enhancers confer the transcriptional regulation of human trophoblast syncytialization. [Nucleic Acids Res. 2023] PubMed

Bat crazy iPSCs. [Cell. 2023] PubMed

Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells. [Genome Res. 2023] PubMed

The giant diploid faba genome unlocks variation in a global protein crop. [Nature. 2023] PubMed

PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates. [Nucleic Acids Res. 2023] PubMed

Mouse embryonic development requires transposable element expression. [Nat Genet. 2023] PubMed

The Interplay Between Developmental Stage and Environment Underlies the Adaptive Effect of a Natural Transposable Element Insertion. [Mol Biol Evol. 2023] PubMed

Transposon-derived transcription factors across metazoans. [Front Cell Dev Biol. 2023] PubMed

Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. [Nat Commun. 2023] PubMed

Retrotransposon-mediated evolutionary rewiring of a pathogen response orchestrates a resistance phenotype in an insect host. [Proc Natl Acad Sci U S A. 2023] PubMed

Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. [Sci Immunol. 2023] PubMed

DNA transposon mechanisms and pathways of genotoxicity. [Mol Ther. 2023] PubMed

Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes. [Nat Commun. 2023] PubMed

The piRNA cluster torimochi is an expanding transposon in cultured silkworm cells. [PLoS Genet. 2023] PubMed

Epigenetic and chromosomal features drive transposon insertion in Drosophila melanogaster. [Nucleic Acids Res. 2023] PubMed

Genetics of sexually dimorphic adipose distribution in humans. [Nat Genet. 2023] PubMed

Off-target piRNA gene silencing in Drosophila melanogaster rescued by a transposable element insertion. [PLoS Genet. 2023]PubMed

Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis. [Cell Rep. 2023] PubMed

RNA-mediated heterochromatin formation at repetitive elements in mammals. [EMBO J. 2023] PubMed

Transcription of MERVL retrotransposons is required for preimplantation embryo development. [Nat Genet. 2023] PubMed

Recent transposable element bursts are associated with the proximity to genes in a fungal plant pathogen. [PLoS Pathog. 2023] PubMed

Timing of integration into the chromosome is critical for the fitness of an integrative and conjugative element and its bacterial host. [PLoS Genet. 2023] PubMed

Pathogenic tau-induced transposable element-derived dsRNA drives neuroinflammation. [Sci Adv. 2023] PubMed

Novel integrative elements and genomic plasticity in ocean ecosystems. [Cell. 2023] PubMed

The Immunological Conundrum of Endogenous Retroelements. [Annu Rev Immunol. 2022] PubMed

Intron-rich dinoflagellate genomes driven by Introner transposable elements of unprecedented diversity. [Curr Biol. 2023] PubMed

The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction. [Nat Commun. 2023] PubMed

The ESKAPE mobilome contributes to the spread of antimicrobial resistance and CRISPR-mediated conflict between mobile genetic elements. [Nucleic Acids Res. 2023] PubMed

Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans. [Proc Natl Acad Sci U S A. 2023][ PubMed

MITE infestation accommodated by genome editing in the germline genome of the ciliate Blepharisma. [Proc Natl Acad Sci U S A. 2023] PubMed

Passer, a highly active transposon from a fish genome, as a potential new robust genetic manipulation tool. [Nucleic Acids Res. 2023][ PubMed

Resurrection of endogenous retroviruses during aging reinforces senescence. [Cell. 2023] PubMed

Is aging a "Retro"spective event? [Cell. 2023] PubMed

Resurrection of endogenous retroviruses during aging reinforces senescence. [Cell. 2023] PubMed

Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements. [PLoS Genet. 2023] PubMed

LINE-1 retrotransposon expression in cancerous, epithelial and neuronal cells revealed by 5' single-cell RNA-Seq. [Nucleic Acids Res. 2023] PubMed

Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development. Nat Commun. 2023 PubMed

A high-quality reference genome for the fission yeast Schizosaccharomyces osmophilus. G3 (Bethesda). 2023 PubMed

Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Sci Immunol. 2023 PubMed

Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. [Sci Immunol. 2023] PubMed

Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors. [Proc Natl Acad Sci USA. 2022] PubMed

An Overview of Best Practices for Transposable Element Identification, Classification, and Annotation in Eukaryotic Genomes. [Methods Mol Biol. 2023] PubMed

Recurrent co-domestication of PIF/Harbinger transposable element proteins in insects. [Mob DNA. 2022] PubMed

Generalized nuclear localization of retroelement transcripts. [Mob DNA. 2022] PubMed

Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells. [Nat Commun. 2022] PubMed

Genomic innovation and regulatory rewiring during evolution of the cotton genus Gossypium. [Nat Genet. 2022] PubMed

Genetic variation in P-element dysgenic sterility is associated with double-strand break repair and alternative splicing of TE transcripts. [PLoS Genet. 2022] PubMed

A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. [Nat Commun. 2022] PubMed

Transposable Elements Continuously Remodel the Regulatory Landscape, Transcriptome, and Function of Decidual Stromal Cells. [Genome Biol Evol. 2022] PubMed

Widespread transposon co-option in the Caenorhabditis germline regulatory network. [Sci Adv. 2022] PubMed

Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells. [Nucleic Acids Res. 2022] PubMed

Discovery and characterization of novel type I-D CRISPR-guided transposons identified among diverse Tn7-like elements in cyanobacteria. [Nucleic Acids Res. 2022] PubMed

Local assembly of long reads enables phylogenomics of transposable elements in a polyploid cell line. [Nucleic Acids Res. 2022] PubMed

Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism. [Cell. 2022] PubMed

Transposable elements and Alzheimer's disease pathogenesis [Trends Neurosci. 2022] PubMed

Stage-specific transposon activity in the life cycle of the fairy-ring mushroom Marasmius oreades. [Proc Natl Acad Sci. 2022] PubMed

Integrase-mediated differentiation circuits improve evolutionary stability of burdensome and toxic functions in E. coli. [Nat Commun. 2022] PubMed

Structures of a mobile intron retroelement poised to attack its structured DNA target. [Science. 2022] PubMed

Somatic recombination of repetitive elements. [Nat Genet. 2022] PubMed

Retrotransposon activation during Drosophila metamorphosis conditions adult antiviral responses. [Nat Genet. 2022] PubMed

Functional characterization of diverse type I-F CRISPR-associated transposons. [Nucleic Acids Res. 2022]  PubMed

Transposable element-mediated rearrangements are prevalent in human genomes. [Nat Commun. 2022] PubMed

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition. [Mob DNA. 2022] PubMed

Developmental timing of programmed DNA elimination in Paramecium tetraurelia recapitulates germline transposon evolutionary dynamics. [Genome Res. 2022] PubMed

TDP-43 safeguards the embryo genome from L1 retrotransposition. [Sci Adv. 2022] PubMed

Transposable elements drive intron gain in diverse eukaryotes. [Proc Natl Acad Sci. 2022] PubMed

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases. [Nat Biotechnol. 202] PubMed

Primate-specific transposable elements shape transcriptional networks during human development. [Nat Commun. 2022] PubMed

Structural basis for the assembly of the type V CRISPR-associated transposon complex. [Cell. 2022] PubMed

Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors. [Genes Genet Syst. 2022] PubMed

Structures of the holo CRISPR RNA-guided transposon integration complex. [Nature. 2022] PubMed

Transposon control as a checkpoint for tissue regeneration. [Development. 2022] PubMed

The coevolution between APOBEC3 and retrotransposons in primates. [Mob DNA. 2022] PubMed

The Epigenetic Control of the Transposable Element Life Cycle in Plant Genomes and Beyond. [Annu Rev Genet. 2022] PubMed

A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles. [Mol Biol Evol. 2022] PubMed

Chromatin remodeling is required for sRNA-guided DNA elimination in Paramecium. [EMBO J. 2022] PubMed

Spatiotemporal variations in retrovirus-host interactions among Darwin's finches. [Nat Commun. 2022] PubMed

Structural insight into Tn3 family transposition mechanism. [Nat Commun. 2022] PubMed

KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA-DNA triplexes and HP1 binding. [Nat Cell Biol. 2022] PubMed

LINE-1 activation in the cerebellum drives ataxia. [Neuron. 2022] PubMed

Widespread expression of the ancient HERV-K (HML-2) provirus group in normal human tissues. [PLoS Biol. 2022] PubMed

A field guide to endogenous retrovirus regulatory networks. [Mol Cell. 2022] PubMed

A unique eukaryotic lineage of composite-like DNA transposons encoding a DDD/E transposase and a His-Me finger homing endonuclease. [Mob DNA. 2022] PubMed

A life LINE for large viruses. [Elife. 2022] PubMed

Evolution and antiviral activity of a human protein of retroviral origin. [Science. 2022] PubMed

Young transposable elements rewired gene regulatory networks in human and chimpanzee hippocampal intermediate progenitors. [Development. 2022] PubMed

LINE-1 activation in the cerebellum drives ataxia. [Neuron. 2022] PubMed

LINE-1 retrotransposons facilitate horizontal gene transfer into poxviruses. [Elife. 2022] PubMed

Poxviruses capture host genes by LINE-1 retrotransposition. [Elife. 2022] PubMed

Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation. [Science. 2022] PubMed

SARS-CoV-2-encoded Inhibitors of Human LINE-1 Retrotransposition. [J Med Virol. 2022] PubMed

Transposable elements. [Curr Biol. 2022] PubMed

Bacterial immunity: Mobile genetic elements are hotspots for defence systems. [Curr Biol. 2022] PubMed

Complex chromosomal rearrangements induced by transposons in maize. [Genetics. 2022] PubMed

Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic. [Ann Neurol. 2022] PubMed

Retrotransposon insertion as a novel mutational cause of spinal muscular atrophy. [Hum Genet. 2022] PubMed

Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm. [Nat Commun. 2022] PubMed

Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain. [Development. 2022] PubMed

Group II intron-like reverse transcriptases function in double-strand break repair. PubMed

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses. [EMBO Rep. 2022] PubMed

Condensin I and condensin II proteins form a LINE-1 dependent super condensin complex and cooperate to repress LINE-1. [Nucleic Acids Res. 2022] PubMed

Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. [Proc Natl Acad Sci U S A. 2022] PubMed

Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1. [J Virol. 2022] PubMed

Uncontrolled transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of Cryptococcus neoformans. [Nat Microbiol. 2022] PubMed

Telomere transposon takeover in Cryptococcus. [Nat Microbiol. 2022] PubMed

Hijacking of transcriptional condensates by endogenous retroviruses. [Nat Genet. 2022] PubMed

The retroelement Lx9 puts a brake on the immune response to virus infection. [Nature. 2022] PubMed

Ruminant-specific retrotransposons shape regulatory evolution of bovine immunity. [Genome Res. 2022] PubMed

LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes. [Sci Transl Med. 2022] PubMed

B-to-A transition in target DNA during retroviral integration. [Nucleic Acids Res. 2022] PubMed

Recent, full-length gene retrocopies are common in canids. [Genome Res. 2022] PubMed

Multiple horizontal transfers of a Helitron transposon associated with a parasitoid wasp. [Mob DNA. 2022] PubMed

The neurodevelopmental gene MSANTD2 belongs to a gene family formed by recurrent molecular domestication of Harbinger transposons at the base of vertebrates. [Mol Biol Evol. 2022] PubMed

Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila. [Elife. 2022] PubMed

Transposable elements contribute to the spatiotemporal microRNA landscape in human brain development. [RNA. 2022] PubMed

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis. [Nat Commun. 2022] PubMed

SCIFER: approach for analysis of LINE-1 mRNA expression in single cells at a single locus resolution. [Mob DNA. 2022] PubMed

Mammalian genome innovation through transposon domestication. [Nat Cell Biol. 202] PubMed

Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. [Nature. 2022] PubMed

Species-specific chromatin landscape determines how transposable elements shape genome evolution. [Elife. 2022] PubMed

Selfish, promiscuous and sometimes useful: how mobile genetic elements drive horizontal gene transfer in microbial populations. [Philos Trans R Soc Lond B Biol Sci. 2022] PubMed

Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors. [Cell. 2022] PubMed

mobileOG-db: a Manually Curated Database of Protein Families Mediating the Life Cycle of Bacterial Mobile Genetic Elements. [Appl Environ Microbiol. 2022] PubMed

The L1-ORF1p coiled coil enables formation of a tightly compacted nucleic acid-bound complex that is associated with retrotransposition. [Nucleic Acids Res. 2022] PubMed

Repurposing CRISPR RNA-guided integrases system for one-step, efficient genomic integration of ultra-long DNA sequences. [Nucleic Acids Res. 2022] PubMed

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition. [Proc Natl Acad Sci U S A. 2022] PubMed

LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer. [Mol Cancer. 2022] PubMed

FTO mediates LINE1 m 6 A demethylation and chromatin regulation in mESCs and mouse development [Science. 2022] PubMed

Reliance of Host-Encoded Regulators of Retromobility on Ty1 Promoter Activity or Architecture. [Front Mol Biosci. 2022] PubMed

Analysis of repeat elements in the Pristionchus pacificus genome reveals an ancient invasion by horizontally transferred transposons. [BMC Genomics. 2022] PubMed

Bacterial retrons encode phage-defending tripartite toxin-antitoxin systems. [Nature. 2022] PubMed

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. [Sci Adv. 2022] PubMed

Sequestration of LINE-1 in cytosolic aggregates by MOV10 restricts retrotransposition. [EMBO Rep. 2022] PubMed

Recombination of repeat elements generates somatic complexity in human genomes. [Cell. 2022] PubMed

Accelerated Evolution by Diversity-Generating Retroelements. [Annu Rev Microbiol. 2022] PubMed

Structural basis of transposon end recognition explains central features of Tn7 transposition systems. [Mol Cell. 2022] PubMed

Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome. [Retrovirology. 2022] PubMed

Amplification of LTRs of extrachromosomal linear DNAs (ALE-seq) identifies two active Oryco LTR retrotransposons in the rice cultivar Dongjin. [Mob DNA. 2022] PubMed

Genomic features underlie the co-option of SVA transposons as cis-regulatory elements in human pluripotent stem cells. [PLoS Genet. 2022] PubMed

Expansion of a retrovirus lineage in the koala genome. [Proc Natl Acad Sci U S A. 2022] PubMed

Somatic retrotransposition in the developing rhesus macaque brain. [Genome Res. 2022] PubMed

Frequency and mechanisms of LINE-1 retrotransposon insertions at CRISPR/Cas9 sites. [Nat Commun. 2022] PubMed

Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration. [J Virol. 2022] PubMed

Transposable element accumulation drives size differences among polymorphic Y Chromosomes in Drosophila. [Genome Res. 2022] PubMed

Identification of an integrase-independent pathway of retrotransposition. [Sci Adv. 2022] PubMed

A multiplexed, three-dimensional pooling and next-generation sequencing strategy for creating barcoded mutant arrays: construction of a Schizosaccharomyces pombe transposon insertion library. [Nucleic Acids Res. 2022] PubMed

Multivalent interactions essential for lentiviral integrase function. [N Commun. 2022] PubMed

HUSH, retrotransposon RNA, you're NEXT to decay. [Mol Cell. 2022] PubMed

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders. [Cell. 2022] PubMed

Taming transposable elements in vertebrates: from epigenetic silencing to domestication. [Trends Genet. 2022] PubMed

Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sub-lines. [Genetics. 2022] PubMed

Reconstruction of full-length LINE-1 progenitors from ancestral genomes. [Genetics. 2022] PubMed

Comprehensive analysis of both long and short read transcriptomes of a clonal and a seed-propagated model species reveal the prerequisites for transcriptional activation of autonomous and non-autonomous transposons in plants. [Mob DNA. 2022] PubMed

On the Base Composition of Transposable Elements. [Int J Mol Sci. 2022] PubMed

NOS2 and S-nitrosothiol signaling induces DNA hypomethylation and LINE-1 retrotransposon expression. [Proc Natl Acad Sci USA. 2022] PubMed

Giant Starship elements mobilize accessory genes in fungal genomes. [Mol Biol Evol. 2022] PubMed

Active endogenous retroviral elements in human pluripotent stem cells play a role in regulating host gene expression. [Nucleic Acids Res. 2022] PubMed

HIV-1 exploits the Fanconi anemia pathway for viral DNA integration. [Cell Rep. 2022] PubMed

Structural basis for RNA-guided DNA cleavage by IscB-ωRNA and mechanistic comparison with Cas9. [Science. 2022] PubMed

A hominoid-specific endogenous retrovirus may have rewired the gene regulatory network shared between primordial germ cells and naïve pluripotent cells. [PLoS Genet. 2022] PubMed

Multimodal Functionalities of HIV-1 Integrase. [Viruses. 2022] PubMed

FTO mediates LINE1 m 6 A demethylation and chromatin regulation in mESCs and mouse development. [Science. 2022] PubMed

Histone chaperone HIRA complex regulates retrotransposons in embryonic stem cells. [Stem Cell Res Ther. 2022] PubMed

Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing. [J Biol Chem. 2022] PubMed

Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome. [Nat Commun. 2022] PubMed

A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci.[Genome Res. 2022] PubMed

Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila. [Nat Commun. 2022] PubMed

Throwing away DNA: programmed downsizing in somatic nuclei. [Trends Genet. 2022] PubMed

Locus-specific expression of transposable elements in single cells with CELLO-seq. [Nat Biotechnol. 2022] PubMed

Repetitive DNA in disease. [Science. 2022] PubMed

Methodologies for the De novo Discovery of Transposable Element Families. [Genes (Basel). 2022] PubMed

Recently Integrated Alu Elements in Capuchin Monkeys: A Resource for Cebus/Sapajus Genomics. [Genes (Basel). 2022] PubMed

Excision and reinsertion of Ac macrotransposons in maize. [Genetics. 2022] PubMed

Activation of class 1 integron integrase is promoted in the intestinal environment. [PLoS Genet. 2022] PubMed

Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells. [Nucleic Acids Res. 2022] PubMed

Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene bla_NDM. [Nat Commun. 2022] PubMed

Transposon insertions regulate genome-wide allele-specific expression and underpin flower colour variations in apple (Malus spp.). [Plant Biotechnol J. 2022] PubMed

A devil's bargain with transposable elements in plant pathogens. [Trends Genet. 2022] PubMed

The essential but enigmatic regulatory role of HERVH in pluripotency. [Trends Genet. 2022] PubMed

Fast co-evolution of anti-silencing systems shapes the invasiveness of Mu-like DNA transposons in eudicots. [EMBO J. 2022] PubMed

A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats. [Nat Commun. 2022] PubMed

Species-specific KRAB-ZFPs function as repressors of retroviruses by targeting PBS regions. [Proc Natl Acad Sci U S A. 2022] PubMed

Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells. [Elife. 2022] PubMed

Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes. [Nucleic Acids Res. 2022] PubMed

Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression. [Mol Cell. 2022] PubMed

Paleozoic Protein Fossils Illuminate the Evolution of Vertebrate Genomes and Transposable Elements. [Mol Biol Evol. 2022] PubMed

From telomere to telomere: The transcriptional and epigenetic state of human repeat elements. [Science. 2022] PubMed

Long-read sequencing of the zebrafish genome reoganizes gemonic architecture. [BMC Genomics. 2022] PubMed

Ineffective silencing of transposable elements on an avian W Chromosome. [Genome Res. 2022] PubMed

Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells. [Nucleic Acids Res. 2022] PubMed

MxB inhibits long interspersed element type 1 retrotransposition. [PLoS Genet. 2022] PubMed

LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint. [Proc Natl Acad Sci USA. 2022] PubMed

Structural basis for DNA targeting by the Tn7 transposon. [Nat Struct Mol Biol. 2022] PubMed

Migrators within migrators: exploring transposable element dynamics in the monarch butterfly, Danaus plexippus. [Mob DNA. 2022] PubMed

Engineered Sleeping Beauty transposase redirects transposon integration away from genes. [Nucleic Acids Res. 2022] PubMed

The widespread nature of Pack-TYPE transposons reveals their importance for plant genome evolution. [PLoS Genet. 2022] PubMed

Eco-evolutionary significance of domesticated retroelements in microbial genomes. [Mob DNA. 2022] PubMed

Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons. [Mol Cell. 2022] PubMed

TransposonUltimate: software for transposon classification, annotation and detection. [Nucleic Acids Res. 2022] PubMed

Nearby transposable elements impact plant stress gene regulatory networks: a meta-analysis in A. thaliana and S. lycopersicum [BMC Genomics. 2022] PubMed

Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression [Genome Res. 2022] PubMed

Unique mobile elements and scalable gene flow at the prokaryote-eukaryote boundary revealed by circularized Asgard archaea genomes [Nat Microbiol. 2022] PubMed

The fifth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements [Mob DNA. 2022] PubMed

Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons [Mol Cell. 2022] PubMed

Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections [Nat Commun. 2022] PubMed

Taming, Domestication and Exaptation: Trajectories of Transposable Elements in Genomes [Cells. 2021] PubMed

Transposable element activation promotes neurodegeneration in a Drosophila model of Huntington's disease [iScience. 2021] PubMed

Cargo Genes of Tn7-Like Transposons Comprise an Enormous Diversity of Defense Systems, Mobile Genetic Elements, and Antibiotic Resistance Genes [mBio. 2021] PubMed

Sex-specific chromatin remodelling safeguards transcription in germ cells [Nature. 2021] PubMed

Targeted insertion of large genetic payloads using cas directed LINE-1 reverse transcriptase [Sci Rep. 2021] PubMed

Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions [Nat Commun. 2021] PubMed

Engines of change: Transposable element mutation rates are high and variable within Daphnia magna [PLoS Genet. 2021] PubMed

Reactivation of transposable elements following hybridization in fission yeast [Genome Res. 2021] PubMed

Innate, translation-dependent silencing of an invasive transposon in Arabidopsis [EMBO Rep. 2021] PubMed

Mobilization of vitamin B₁₂ transporters alters competitive dynamics in a human gut microbe [Cell Rep. 2021] PubMed

A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary [Genetics. 2021) PubMed

A nuclear pore sub-complex restricts the propagation of Ty retrotransposons by limiting their transcription [PLoS Genet. 2021] PubMed

The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities [Philos Trans R Soc Lond B Biol Sci. 2021] PubMed

BST2 suppresses LINE-1 retrotransposition by reducing the promoter activity of LINE-1 5'-UTR [J Virol. 2021] PubMed

The local integration preference of the Tf1 retrotransposon in Schizosaccharomyces pombe [Virology. 2021] PubMed

Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks [Mol Cell. 2021] PubMed

Transposable elements that have recently been mobile in the human genome [BMC Genomics. 2021] PubMed

Chromosomal integration of Tn5253 occurs downstream of a conserved 11-bp sequence of the rbgA gene in Streptococcus pneumoniae and in all the other known hosts of this integrative conjugative element (ICE) [Mob DNA. 2021] Pubmed

Target site selection and remodelling by type V CRISPR-transposon systems [Nature. 2021] PubMed

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation [Nat Commun. 2021] PubMed

Transposable elements shape the evolution of mammalian development [Nat Rev Genet. 2021] PubMed

Methylation patterns of Tf2 retrotransposons linked to rapid adaptive stress response in the brown planthopper (Nilaparvata lugens)[Genomics. 2021] PubMed

A comparative analysis of L1 retrotransposition activities in human genomes suggests an ongoing increase in L1 number despite an evolutionary trend towards lower activity [Mob DNA. 2021] PubMed

Genome surveillance by HUSH-mediated silencing of intronless mobile elements [Nature. 2021] PubMed

A new RNA-DNA interaction required for integration of group II intron retrotransposons into DNA targets [Nucleic Acids Res. 2021] PubMed

Comparative analysis of transposable elements provides insights into genome evolution in the genus Camelus [BMC Genomics. 2021] PubMed

Transposable elements mark a repeat-rich region associated with migratory phenotypes of willow warblers (Phylloscopus trochilus) [Mol Ecol. 2021] PubMed

Population analysis of retrotransposons in giraffe genomes supports RTE decline and widespread LINE1 activity in Giraffidae [Mob DNA. 2021] PubMed

A transposon expression burst accompanies the activation of Y-chromosome fertility genes during Drosophila spermatogenesis [Nat Commun. 2021] PubMed

Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing [PLoS Genet. 2021] PubMed

Is the bacterial chromosome a mobile genetic element? [Nat Commun. 2021] PubMed

Genome surveillance by HUSH-mediated silencing of intronless mobile elements [Nature. 2021] PubMed

A new RNA-DNA interaction required for integration of group II intron retrotransposons into DNA targets [Nucleic Acids Res. 2021] PubMed

Segregating complete Tf2 elements are largely neutral in fission yeast [Genome Biol Evol. 2021] PubMed

Whole-genome analysis reveals the contribution of non-coding de novo transposon insertions to autism spectrum disorder [Mob DNA. 2021] PubMed

Metagenomic discovery of CRISPR-associated transposons [Proc Natl Acad Sci U S A. 2021] PubMed

The genomic ecosystem of transposable elements in maize [PLoS Genet. 2021] PubMed

Pif1 helicases and the evidence for a prokaryotic origin of Helitrons [Mol Biol Evol. 2021] PubMed

Transposable element profiles reveal cell line identity and loss of heterozygosity in Drosophila cell culture [Genetics. 2021] PubMed

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The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases [Science. 2021] PubMed

PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation [Cell Rep. 2021] PubMed

Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation [Mol Cell. 2021] Cell Press

Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease [Nature. 2021] PubMed

Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability [Mol Cell. 2021] PubMed

Transposon-taming piRNAs in the germline: Where do they come from? [Mol Cell. 2021] PubMed

Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75 [Nucleic Acids Res. 2021] PubMed

Transposable elements shape the evolution of mammalian development [Nature Reviews Genetics. 2021] Nature

A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development [Cell. 2021] PubMed

Sequence features of retrotransposons allow for epigenetic variability [Elife. 2021] PubMed

KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements [Nature. 2021] PubMed

Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages [Science. 2021] Science

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Proteome-wide profiling of transcriptional machinery on accessible chromatin with biotinylated transposons [Sci Adv. 2021] PubMed

Structural insights into the evolution of the RAG recombinase [Nat Rev Immunol. 2021] PubMed

Embryonic LTR retrotransposons supply promoter modules to somatic tissues [Genome Res. 2021] PubMed

Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development [Genome Res. 2021] PubMed

Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate [Elife. 2021] PubMed

Mobile element insertions and associated structural variants in longitudinal breast cancer samples [Sce Rep. 2021] PubMed

Comparative genomic and transcriptomic analyses of transposable elements in polychaetous annelids highlight LTR retrotransposon diversity and evolution [Mob DNA. 2021] PubMed

Bracoviruses recruit host integrases for their integration into caterpillar's genome [PLoS Genet. 2021] PubMed

Regulation of retrotransposition in Arabidopsis [Biochem Soc Trans. 2021] PubMed

Circular RNA repertoires are associated with evolutionarily young transposable elements [Elife. 2021) PubMed

Characterization of full-length LINE-1 insertions in 154 genomes [Genomics. 2021] PubMed

piRNA-independent transposon silencing by the Drosophila THO complex [Dev Cell. 2021] PubMed

The function of twister ribozyme variants in non-LTR retrotransposition in Schistosoma mansoni [Nucleic Acids Res. 2021] PubMed

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Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease [Nucleic Acids Res. 2021] PubMed

Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control [Nat Commun. 2021] PubMed

PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta [Development. 2021] PubMed

Transposon-triggered innate immune response confers cancer resistance to the blind mole rat [Nat Immunol. 2021] PubMed

You can keep your coat on [Elife. 2021] PubMed

An L1 retrotransposon insertion-induced deafness mouse model for studying the development and function of the cochlear stria vascularis [Proc Natl Acad Sci U S A. 2021] PubMed

Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas [Nature. 2021] PubMed

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing [Cell Rep. 2021] PubMed

The role of the Cer1 transposon in horizontal transfer of transgenerational memory [Cell. 2021] PubMed

The role of retrotransposable elements in ageing and age-associated diseases [Nature. 2021] PubMed

SorTn-seq: a high-throughput functional genomics approach to discovering regulators of bacterial gene expression [Nat Protoc. 2021] PubMed

The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end [Mol Cell. 2021] PubMed

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures [Nat Commun. 2021] PubMed

Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro [J Biol Chem. 2021] PubMed

Genomic islands targeting dusA in Vibrio species are distantly related to Salmonella Genomic Island 1 and mobilizable by IncC conjugative plasmids [PLoS Genet. 2021] PubMed

Structural basis for target site selection in RNA-guided DNA transposition systems [Science. 2021] PubMed

Sequence specific integration by the family 1 casposase from Candidatus Nitrosopumilus koreensis AR1 [Nucleic Acids Res. 2021] PubMed

Transposon debris in ciliate genomes [PLoS Biol. 2021] PubMed

Disintegration promotes protospacer integration by the Cas1-Cas2 complex [Elife. 2021] PubMed

The RNA editing enzyme ADAR2 restricts L1 mobility [RNA Biol. 2021] PubMed

Cognate restriction of transposition by piggyBac-like proteins [Nucleic Acids Res. 2021] PubMed

Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis [Elife. 2021] PubMed

Structure and function of retroviral integrase [Nat Rev Microbiol. 2021] PubMed

Elevated retrotransposon activity and genomic instability in primed pluripotent stem cells [Genome Biol. 2021] PubMed

DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans [Nat Commun. 2021] PubMed

Distinct retrotransposon evolution profile in the genome of rabbit (Oryctolagus cuniculus) [Genome Biol Evol. 2021] PubMed

An ancient clade of Penelope-like retroelements with permuted domains is present in the green lineage and protists, and dominates many invertebrate genomes [Mol Biol Evol. 2021] PubMed

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing [Cell Rep. 2021] PubMed

The Rhox gene cluster suppresses germline LINE1 transposition [Proc Natl Acad Sci U S A. 2021] PubMed

Reproducible and accessible analysis of transposon insertion sequencing in Galaxy for qualitative essentiality analyses [BMC Microbiol. 2021] PubMed

Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing [Mob DNA. 2021] PubMed

RNA m⁶A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability [Cell Res. 2021] PubMed

Nascent RNA m⁶A modification at the heart of the gene-retrotransposon conflict [Cell Res. 2021] PubMed

Species-wide transposable element repertoires retrace the evolutionary history of the Saccharomyces cerevisiae host [Mol Biol Evol. 2021] PubMed

RNA-directed DNA methylation prevents rapid and heritable reversal of transposon silencing under heat stress in Zea mays [PLoS Genet. 2021] PubMed

Switching Sides: How Endogenous Retroviruses Protect Us from Viral Infections [J Virol. 2021] PubMed

Retrieval of vector integration sites from cell-free DNA [Nat Med. 2021] PubMed

Dnmt1 has de novo activity targeted to transposable elements [Nat Struct Mol Biol. 2021] PubMed

Comprehensive identification of transposable element insertions using multiple sequencing technologies [Nat Commun. 2021] PubMed

rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo [Nucleic Acids Res. 2021] PubMed

Organ-, sex- and age-dependent patterns of endogenous L1 mRNA expression at a single locus resolution [Nucleic Acids Res. 2021] PubMed

Evolution of mouse circadian enhancers from transposable elements [Genome Biol. 2021] PubMed

A Long, Fulfilling Career in Human Genetics [Annu Rev Genomics Hum Genet. 2021] PubMed

DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation [Nat Commun. 2021] PubMed

Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3 [Cell Stem Cell. 2021] PubMed

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues [Proc Natl Acad Sci U S A. 2021] PubMed

A cis-regulatory atlas in maize at single-cell resolution [Cell. 2021] PubMed

Sample sequence analysis uncovers recurrent horizontal transfers of transposable elements among grasses [Mol Biol Evol. 2021] PubMed

CRISPR transposons on the move [Cell Host Microbe. 2021] PubMed

Prokaryotic reverse transcriptases: from retroelements to specialized defense systems [FEMS Microbiol Rev. 2021] PubMed

INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication [Nat Commun. 2021] PubMed

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline [Genes Dev. 2021] PubMed

Repetitive DNA: genomic dark matter matters [Nat Rev Genet. 2021] PubMed

Cassette recruitment in the chromosomal Integron of Vibrio cholera [Nucleic Acids Res. 2021] PubMed

You can keep your coat on [Elife. 2021] PubMed

Long-read assembly of a Great Dane genome highlights the contribution of GC-rich sequence and mobile elements to canine genomes. [Proc Natl Acad Sci U S A. 2021] PubMed

Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia. [Nat Genet. 2021] PubMed

The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W. [Nat Cell Biol. 2021] PubMed

Alternative splicing is a developmental switch for hTERT expression. [Mol Cell. 2021] PubMed

Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. [Sci Rep. 2021] PubMed

Transposons Increase Transcriptional Complexity: The Good Parasite? [Trends Genet. 2021] PubMed

Unearthing LTR retrotransposon gag genes co-opted in the deep evolution of eukaryotes. [Mol Biol Evol. 2021] PubMed

The Enterprise, a massive transposon carrying Spok meiotic drive genes. [Genome Res. 2021] PubMed

Sensing of transposable elements by the antiviral innate immune system. [RNA. 2021] PubMed

Intercellular viral spread and intracellular transposition of Drosophila gypsy. [PLoS Genet. 2021] PubMed

Transposon-induced inversions activate gene expression in the maize pericarp. [Genetics. 2021] PubMed

The unusual structure of the PiggyMac cysteine-rich domain reveals zinc finger diversity in PiggyBac-related transposases. [Mob DNA. 2021] PubMed

Ribosome stalling and SGS3 phase separation prime the epigenetic silencing of transposons. [Nat Plants. 2021] PubMed

The association of group IIB intron with integrons in hypersaline environments. [Mob DNA. 2021] PubMed

The RNA m⁶A reader YTHDC1 silences retrotransposons and guards ES cell identity. [Nature. 2021] PubMed

Assessing the regulatory potential of transposable elements using chromatin accessibility profiles of maize transposons. [Genetics. 2021] PubMed

Methylation of rRNA as a host defense against rampant group II intron retrotransposition. [Mob DNA. 2021] PubMed

A CRISPR-Cas9-integrase complex generates precise DNA fragments for genome integration. [Nucleic Acids Res. 2021] PubMed

Characterization of an active LINE-1 in the naked mole-rat genome. [Sci Rep. 2021] PubMed

Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. [Commun Biol. 2021] PubMed

Asexual experimental evolution of yeast does not curtail transposable elements. [Mol Biol Evol. 2021] PubMed

A spontaneous genetically-induced epiallele at a retrotransposon shapes host genome function. [Elife. 2021] PubMed

New Ther1-derived SINE Squam3 in scaled reptiles. [Mob DNA. 2021] PubMed

The Integration Preference of Sleeping Beauty at Non-TA Site Is Related to the Transposon End Sequences. [Front Genet. 2021] PubMed

Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. [Cell Rep. 2021] PubMed

Investigating the Potential Roles of SINEs in the Human Genome. [Annu Rev Genomics Hum Genet. 2021] PubMed

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration. [Proc Natl Acad Sci U S A. 2021] PubMed

Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila. [Elife. 2021] PubMed

African lungfish genome sheds light on the vertebrate water-to-land transition. [Cell. 2021] PubMed

Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses. [PLoS Pathog. 2021] PubMed

L1 retrotransposons exploit RNA m⁶A modification as an evolutionary driving force. [Nat Commun. 2021] PubMed

RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs. [Mob DNA. 2021] PubMed

Light and shadow on the mechanisms of integration site selection in yeast Ty retrotransposon families. [Curr Genet. 2021] PubMed

Transposable element landscape in Drosophila populations selected for longevity. [Genome Biol Evol. 2021] PubMed

Transposable element mobilization in interspecific yeast hybrids. [Genome Biol Evol. 2021] PubMed

Recurrent evolution of vertebrate transcription factors by transposase capture. [Science. 2021] PubMed

LINE retrotransposons characterize mammalian tissue-specific and evolutionarily dynamic regulatory regions. [Genome Biol. 2021] PubMed

Genomic properties of variably methylated retrotransposons in mouse. [Mob DNA. 2021] PubMed

Transposon-Associated CRISPR-Cas System: A Powerful DNA Insertion Tool. [Trends Microbiol. 2021] PubMed

A native, highly active Tc1/mariner transposon from zebrafish (ZB) offers an efficient genetic manipulation tool for vertebrates. [Nucleic Acids Res. 2021] PubMed

Unraveling the features of somatic transposition in the Drosophila intestine. [EMBO J. 2021] PubMed

yama, a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis. [PLoS Genet. 2021] PubMed

Transcriptional activity of transposable elements along an elevational gradient in Arabidopsis arenosa. [Mob DNA. 2021] PubMed

m⁶A RNA methylation regulates the fate of endogenous retroviruses [Nature. 2021] PubMed

A transposon surveillance mechanism that safeguards plant male fertility during stress. [Nat Plants. 2021] PubMed

TFs for TEs: the transcription factor repertoire of mammalian transposable elements. [Genes Dev. 2021] PubMed

Meiosis, a New Playground for Retrotransposon Evolution. [Dev Cell. 2021] PubMed

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia. [Nat Neurosci. 2021] PubMed

Jumping Ahead with Sleeping Beauty: Mechanistic Insights into Cut-and-Paste Transposition. [Viruses. 2021] PubMed

Transposable Element Regulation and Expression in Cancer. [FEBS J. 2021] PubMed

Association analysis of repetitive elements and R-loop formation across species. [Mob DNA. 2021] PubMed

HIV Capsid and Integration Targeting. [Viruses. 2021] PubMed

METTL3 regulates heterochromatin in mouse embryonic stem cells. [Nature. 2021] PubMed

Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells. [Proc Natl Acad Sci U S A. 2020] PubMed 

Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling [Mol Cell 2020] PubMed

Upregulation of a KN1 homolog by transposon insertion promotes leafy head development in lettuce. [Proc Natl Acad Sci U S A. 2020] PubMed

Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression. [Genes Dev. 2020] PubMed

Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals. [Mob DNA. 2020] PubMed

SeqURE - a new copy-capture based method for sequencing of unknown Retroposition events. [Mob DNA. 2020] PubMed

Factors that mold the nuclear landscape of HIV-1 integration. [Nucleic Acids Res. 2020] PubMed

Effects of activation of the LINE-1 antisense promoter on the growth of cultured cells. [Sci Rep. 2020] PubMed

Aging-associated distinctive DNA methylation changes of LINE-1 retrotransposons in pure cell-free DNA from human blood. [Sci Rep. 2020] PubMed

Meiosis: Is Spermatogenesis Stress an Opportunity for Evolutionary Innovation? [Curr Biol. 2020] PubMed

Mechanism and regulation of P element transposition. [Open Biol. 2020] PubMed

Mutations altering acetylated residues in the CTD of HIV-1 integrase cause defects in proviral transcription at early times after integration of viral DNA. [PLoS Pathog. 2020] PubMed

Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons. [Elife. 2020] PubMed

Guide RNA Categorization Enables Target Site Choice in Tn7-CRISPR-Cas Transposons [Cell. 2020] PubMed

Determinants of adenine-mutagenesis in diversity-generating retroelements. [Nucleic Acids Res. 2020] PubMed

Deep learning for HGT insertion sites recognition. [BMC Genomics. 2020] PubMed

The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s. [Nat Commun. 2020] PubMed

Gtsf1 is essential for proper female sex determination and transposon silencing in the silkworm, Bombyx mori. [PLoS Genet. 2020] PubMed

Measuring and interpreting transposable element expression [Nat Rev Genet. 2020] PubMed

Broad noncoding transcription suggests genome surveillance by RNA polymerase V. [Proc Natl Acad Sci U S A. 2020] PubMed

CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering. [Nat Biotechnol. 2020] PubMed

Meiotic Cells Counteract Programmed Retrotransposon Activation via RNA-Binding Translational Repressor Assemblies. [Dev Cell. 2020] PubMed

Guide RNA Categorization Enables Target Site Choice in Tn7-CRISPR-Cas Transposons. [Cell. 2020] PubMed

HK022 bacteriophage Integrase mediated RMCE as a potential tool for human gene therapy. [Nucleic Acids Res. 2020] PubMed

Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. [EMBO J. 2020] PubMed

TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control. [Nat Commun. 2020] PubMed

Disentangling the determinants of transposable elements dynamics in vertebrate genomes using empirical evidences and simulations. [PLoS Genet. 2020] PubMed

Transposon activation is a major driver in the genome evolution of cultivated olive trees (Olea europaea L.). [Plant Genome. 2020] PubMed

Genomic diversity generated by a transposable element burst in a rice recombinant inbred population. [Proc Natl Acad Sci U S A. 2020] PubMed

Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ. [Nat Commun. 2020] PubMed

Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. [Science. 2020] PubMed

Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division. [Genome Res. 2020] PubMed

p53 directly represses human LINE1 transposons. [Genes Dev. 2020] PubMed

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option. [Nat Genet. 2020] PubMed

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency. [Nature. 2020] PubMed

A new role for histone demethylases in the maintenance of plant genome integrity. [Elife. 2020] PubMed

Group II introns generate functional chimeric relaxase enzymes with modified specificities through exon shuffling at both the RNA and DNA level. [Mol Biol Evol. 2020] PubMed

Identification of bona fide B2 SINE retrotransposon transcription through single-nucleus RNA-seq of the mouse hippocampus. [Genome Res. 2020] PubMed

Transposon Insertion Sequencing, a Global Measure of Gene Function. [Annu Rev Genet. 2020] PubMed

Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons. [Sci Adv. 2020] PubMed

Satellite DNA-like repeats are dispersed throughout the genome of the Pacific oyster Crassostrea gigas carried by Helentron non-autonomous mobile elements. [Sci Rep. 2020] PubMed

Latest Advances for the Sleeping Beauty Transposon System: 23 Years of Insomnia but Prettier than Ever: Refinement and Recent Innovations of the Sleeping Beauty Transposon System Enabling Novel, Nonviral Genetic Engineering Applications. [Bioessays. 2020] PubMed

Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. [Proc Natl Acad Sci U S A. 2020] PubMed

Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase. [EMBO J. 2020] PubMed

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis. [Elife. 2020] PubMed

Role of diversity-generating retroelements for regulatory pathway tuning in cyanobacteria. [BMC Genomics. 2020] PubMed

Transposon expression in the Drosophila brain is driven by neighboring genes and diversifies the neural transcriptome. [Genome Res. 2020] PubMed

Host Gene Regulation by Transposable Elements: The New, the Old and the Ugly. [Viruses. 2020] PubMed

Evolution of pogo, a separate superfamily of IS630-Tc1-mariner transposons, revealing recurrent domestication events in vertebrates. [Mob DNA. 2020] PubMed

Cryptic genetic variation enhances primate L1 retrotransposon survival by enlarging the functional coiled coil sequence space of ORF1p. [PLoS Genet. 2020] PubMed

Processing of Alu small RNAs by DICER/ADAR1 complexes and their RNAi targets. [RNA. 2020] PubMed

Structural basis of seamless excision and specific targeting by piggyBac transposase. [Nat Commun. 2020] PubMed

Human TRIM5α senses and restricts LINE-1 elements. [Proc Natl Acad Sci U S A. 2020] PubMed

Dnmt1 binds and represses genomic retroelements via DNA methylation in mouse early embryos. [Nucleic Acids Res. 2020] PubMed

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. [Nat Commun. 2020] PubMed

Ranking essential bacterial processes by speed of mutant death. [Proc Natl Acad Sci U S A. 2020] PubMed

TE-greedy-nester: structure-based detection of LTR retrotransposons and their nesting. [Bioinformatics. 2020] PubMed

The unusual dRemp retrotransposon is abundant, highly mutagenic, and mobilized only in the second pollen mitosis of some maize lines. [Proc Natl Acad Sci U S A. 2020] PubMed

AlbaTraDIS: Comparative analysis of large datasets from parallel transposon mutagenesis experiments. [PLoS Comput Biol. 2020] PubMed

A small targeting domain in Ty1 integrase is sufficient to direct retrotransposon integration upstream of tRNA genes. [EMBO J. 2020] PubMed

LINE-1 ORF1p does not determine substrate preference for human/orangutan SVA and gibbon LAVA. [Mob DNA. 2020] PubMed

Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality. [Curr Genet. 2020] PubMed

Co-option of the lineage-specific LAVA retrotransposon in the gibbon genome. [Proc Natl Acad Sci U S A. 2020] PubMed

An NMR-based approach reveals the core structure of the functional domain of SINEUP lncRNAs. [Nucleic Acids Res. 2020] PubMed

Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells. [Cell. 2020] PubMed

Endogenous Retroviruses Walk a Fine Line between Priming and Silencing. [Viruses. 2020] PubMed

A Transposon Story: From TE Content to TE Dynamic Invasion of Drosophila Genomes Using the Single-Molecule Sequencing Technology from Oxford Nanopore. [Cells. 2020] PubMed

A bipartite thermodynamic-kinetic contribution by an activating mutation to RDF-independent excision by a phage serine integrase. [Nucleic Acids Res. 2020] PubMed

KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage. [Elife. 2020] PubMed 

Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates. [Elife. 2020] PubMed 

Hagfish genome reveals parallel evolution of 7SL RNA-derived SINEs. [Mob DNA. 2020] PubMed 

Essential factors involved in the precise targeting and insertion of telomere-specific non-LTR retrotransposon, SART1Bm. [Sci Rep. 2020] PubMed

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons. [PLoS Genet. 2020] PubMed

poly(UG)-tailed RNAs in genome protection and epigenetic inheritance. [Nature. 2020] PubMed

Comment on "RNA-guided DNA insertion with CRISPR-associated transposases". [Science. 2020] PubMed

Silence at the End: How Drosophila Regulates Expression and Transposition of Telomeric Retroelements. [J Mol Biol. 2020] PubMed

The linker region of LINEs modulates DNA cleavage and DNA polymerization. [Anal Biochem. 2020] PubMed

Close-up: HIV/SIV intasome structures shed new light on integrase inhibitor binding and viral escape mechanisms. [FEBS J. 2020] PubMed

H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction. [Proc Natl Acad Sci U S A. 2020] PubMed

Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters. [Proc Natl Acad Sci U S A. 2020] PubMed

Additional ORFs in Plant LTR-Retrotransposons. [Front Plant Sci. 2020] PubMed

Transcriptional regulation of genes bearing intronic heterochromatin in the rice genome. [PLoS Genet. 2020] PubMed

Transposon-mediated telomere destabilization: a driver of genome evolution in the blast fungus. [Nucleic Acids Res. 2020] PubMed

Measuring and interpreting transposable element expression. [Nat Rev Genet. 2020] PubMed 

The Simons Genome Diversity Project: a global analysis of mobile element diversity. [Genome Biol Evol. 2020] PubMed

Real-time observation of CRISPR spacer acquisition by Cas1-Cas2 integrase. [Nat Struct Mol Biol. 2020] PubMed 

piRNA and transposon dynamics in Drosophila: a female story. [Genome Biol Evol. 2020] PubMed 

Viral infection impacts transposable element transcript amounts in Drosophila. [Proc Natl Acad Sci U S A. 2020] PubMed 

Gapless assembly of maize chromosomes using long-read technologies. [Genome Biol. 2020] PubMed

Subfamily-specific quantification of endogenous mouse L1 retrotransposons by droplet digital PCR. [Anal Biochem. 2020] PubMed

Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes. [Nucleic Acids Res. 2020] PubMed 

Toxin-Antitoxin Gene Pairs Found in Tn3 Family Transposons Appear To Be an Integral Part of the Transposition Module. [mBio. 2020] PubMed

The UCSC repeat browser allows discovery and visualization of evolutionary conflict across repeat families. [Mob DNA. 2020] PubMed

TranspoScope - Interactive Visualization of Retrotransposon Insertions. [Bioinformatics. 2020] PubMed

RepeatModeler2 for automated genomic discovery of transposable element families. [Proc Natl Acad Sci U S A. 2020] PubMed

Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro. [Proc Natl Acad Sci U S A. 2020] PubMed

Heat stress-induced transposon activation correlates with 3D chromatin organization rearrangement in Arabidopsis. [Nat Commun. 2020] PubMed

Small RNA-Mediated de Novo Silencing of Ac/Ds Transposons Is Initiated by Alternative Transposition in Maize. [Genetics. 2020] PubMed

AcademH, a lineage of Academ DNA transposons encoding helicase found in animals and fungi. [Mob DNA. 2020] PubMed

A chromosome-scale assembly of the smallest Dothideomycete genome reveals a unique genome compaction mechanism in filamentous fungi. [BMC Genomics. 2020] PubMed

Diverse transposable element landscapes in pathogenic and nonpathogenic yeast models: the value of a comparative perspective. [Mob DNA. 2020] PubMed

Transposon age and non-CG methylation [Nat Commun. 2020] PubMed

RNA-guided retargeting of Sleeping Beauty transposition in human cells. [Elife. 2020] PubMed

Restriction Enzyme Based Enriched L1Hs Sequencing (REBELseq): A Scalable Technique for Detection of Ta Subfamily L1Hs in the Human Genome. [G3 (Bethesda). 2020] PubMed

Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons. [Proc Natl Acad Sci U S A. 2020] PubMed

Horizontal transfer and evolution of transposable elements in vertebrates. [Nat Commun. 2020] PubMed

New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements. [Nucleic Acids Res. 2020] PubMed

Nanopore sequencing and Hi-C scaffolding provide insight into the evolutionary dynamics of transposable elements and piRNA production in wild strains of Drosophila melanogaster. [Nucleic Acids Res. 2020] PubMed

The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans. [Genome Biol. 2019] PubMed

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization. [Nucleic Acids Res. 2020] PubMed

A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons. [Nucleic Acids Res. 2020] PubMed

Silencing of Mu Elements in Maize Involves Distinct Populations of Small RNAs and Distinct Patterns of DNA Methylation. [Genetics. 2020] PubMed

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition [Nat Genet. 2020] PubMed

LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites [Mob DNA 2020] PubMed

BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells [Nat Struct Mol Biol 2020] PubMed

Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication [Nat Struct Mol Biol 2020] PubMed

Transposon Insertion Mutagenesis in Mice for Modeling Human Cancers: Critical Insights Gained and New Opportunities [Int J Mol Sci 2020] PubMed

Dynamic evolution of de novo DNA methyltransferases in rodent and primate genomes [Mol Biol Evol 2020] PubMed

On transposons and totipotency [Philos Trans R Soc Lond B Biol Sci 2020] PubMed

sRNA/L1 retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay [Philos Trans R Soc Lond B Biol Sci 2020] PubMed

Construction and characterization of a knock-down RNA interference line of OsNRPD1 in rice (Oryza sativa ssp japonica cv Nipponbare) [Philos Trans R Soc Lond B Biol Sci 2020] PubMed

Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells [Philos Trans R Soc Lond B Biol Sci 2020] PubMed

Evolution of Ty1 copy number control in yeast by horizontal transfer and recombination [PLoS Genet 2020] PubMed

Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation [Cell Rep 2020] PubMed

Integrated Mobile Element Scanning (ME-Scan) method for identifying multiple types of polymorphic mobile element insertions [Mob DNA 2020] PubMed

LINE-1 ORF2p expression is nearly imperceptible in human cancers [Mob DNA 2019] PubMed

A benchmark of transposon insertion detection tools using real data [Mob DNA 2019] PubMed

Tools and best practices for retrotransposon analysis using high-throughput sequencing data [Mob DNA 2019] PubMed

A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells [Mob DNA 2019] PubMed

Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins [Nat Neurosci 2020] PubMed

Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas [Elife 2020] PubMed

Retroviral Insertional Mutagenesis in Humans: Evidence for Four Genetic Mechanisms Promoting Expansion of Cell Clones [Mol Ther 2020] PubMed

Independent Transposon Exaptation is a Widespread Mechanism of Redundant Enhancer Evolution in the Mammalian Genome [Genome Biol Evol 2020] PubMed

Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity [Nat Commun 2020] PubMed

DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts [Mol Cell 2020] PubMed

Compensating for over-production inhibition of the Hsmar1 transposon in Escherichia coli using a series of constitutive promoters [Mob DNA 2020] PubMed

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase [Cell 2020] PubMed

Evolutionary entanglement of mobile genetic elements and host defence systems: guns for hire [Nat Rev Genet 2020] PubMed

Our Conflict with Transposable Elements and Its Implications for Human Disease [Annu Rev Pathol 2020] PubMed

Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize [PLoS Biol 2020] PubMed

Structural basis of second-generation HIV integrase inhibitor action and viral resistance [Science 2020] PubMed

Structural basis for strand transfer inhibitor binding to HIV intasomes [Science 2020] PubMed

Alu insertion polymorphisms shared by Papio baboons and Theropithecus gelada reveal an intertwined common ancestry [Mob DNA 2019] PubMed

Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA [Nucleic Acids Res 2019] PubMed

Completion of LINE integration involves an open '4-way' branched DNA intermediate [Nucleic Acids Res 2019] PubMed

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements [Elife 2019] PubMed

Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development [Elife 2019] PubMed

Plant gene editing through de novo induction of meristems [Nat Biotechnol 2019] PubMed

Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system [Nature 2019] PubMed

Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology [Nucleic Acids Res 2019] PubMed

Nucleotide composition of transposable elements likely contributes to AT/GC compositional homogeneity of teleost fish genomes [Mob DNA 2019] PubMed

LTR_FINDER_parallel: parallelization of LTR_FINDER enabling rapid identification of long terminal repeat retrotransposons [Mob DNA 2019] PubMed

A Bioinformatic Analysis of Integrative Mobile Genetic Elements Highlights Their Role in Bacterial Adaptation [Cell Host Microbe 2019] PubMed

Nested plant LTR retrotransposons target specific regions of other elements, while all LTR retrotransposons often target palindromes and nucleosome-occupied regions: in silico study [Mob DNA 2019] PubMed

NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase [Retrovirology 2019] PubMed

A highly soluble Sleeping Beauty transposase improves control of gene insertion [Nat Biotechnol 2019] PubMed

Structures of a RAG-like transposase during cut-and-paste transposition [Nature 2019] PubMed

Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus [PLoS Pathog 2019] PubMed

Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells [Cell Rep 2019] PubMed

Targeted insertional mutagenesis libraries for deep domain insertion profiling [Nucleic Acids Res 2019] PubMed

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming [Nucleic Acids Res 2019] PubMed

Pedigree-based Estimation of Human Mobile Element Retrotransposition Rates [Genome Res 2019] PubMed 

Retrons and their applications in genome engineering [Nucleic Acids Res 2019] PubMed

The Transposon Registry [Mob DNA 2019]

Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts [Nat Struct Mol Biol 2019] PubMed

Expansion of a single transposable element family is associated with genome-size increase and radiation in the genus Hydra [Proc Natl Acad Sci USA 2019] PubMed

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [Cell Rep 2019] PubMed

Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function
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Host-transposon interactions: conflict, cooperation, and cooption [Genes Dev 2019] PubMed

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse [Cell 2019] PubMed

Transcriptome analyses of tumor-adjacent somatic tissues reveal genes co-expressed with transposable elements [Mob DNA 2019] PubMed

The Gypsy Endogenous Retrovirus Drives Non-Cell-Autonomous Propagation in a Drosophila TDP-43 Model of Neurodegeneration [Curr Biol 2019] PubMed

Targeted transposition with Tn7 elements: Safe sites, mobile plasmids, CRISPR/Cas and beyond [Mol Microbiol 2019] PubMed

The Arms Race Between KRAB-Zinc Finger Proteins and Endogenous Retroelements and Its Impact on Mammals [Annu Rev Genet 2019] PubMed

Environmental and epigenetic regulation of Rider retrotransposons in tomato [PLoS Genet 2019] PubMed

LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly [Genome Res 2019] PubMed

Transposition: A CRISPR Way to Get Around [Curr Biol 2019] PubMed

RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA [Proc Natl Acad Sci USA 2019] PubMed

Pedigree-based estimation of human mobile element retrotransposition rates [Genome Res 2019] PubMed

Targeted DNA transposition in vitro using a dCas9-transposase fusion protein [Nucleic Acids Res 2019] PubMed

Successful invasions of short internally deleted elements (SIDEs) and its partner CR1 in Lepidoptera insects [Genome Biol Evol 2019] PubMed

Study of VIPER and TATE in kinetoplastids and the evolution of tyrosine recombinase retrotransposons [Mob DNA 2019] PubMed

A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production [Cell 2019] PubMed

LINE-1 Evasion of Epigenetic Repression in Humans [Molecular Cell 2019] PubMed

TeXP: Deconvolving the effects of pervasive and autonomous transcription of transposable elements [PLoS Comput Biol 2019] PubMed

RNA-guided DNA insertion with CRISPR-associated transposases. [Science 2019] PubMed

Multifaceted HIV integrase functionalities and therapeutic strategies for their inhibition [J Biol Chem 2019] PubMed

Variable genome evolution in fungi after transposon-mediated amplification of a housekeeping gene [Mob DNA 2019] PubMed

Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon [Proc Natl Acad Sci USA 2019] PubMed

Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition [Mol Cell 2019] PubMed

Paired-end mappability of transposable elements in the human genome. [Mob DNA 2019] PubMed

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. [Nat Commun. 2019] PubMed

The RNA exosome nuclease complex regulates human embryonic stem cell differentiation. [J Cell Biol. 2019] PubMed

Cryo-EM Structures of a Group II Intron Reverse Splicing into DNA. [Cell 2019] PubMed

Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease. [Mob DNA 2019] 

Transposition favors the generation of large effect mutations that may facilitate rapid adaption. [Nat Commun. 2019] PubMed

Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration [Nature. 2019] PubMed

Giant Transposons in Eukaryotes: Is Bigger Better? [Genome Biol Evol. 2019] PubMed

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina [Nucleic Acids Res. 2019] PubMed

Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion [Genome Biol. 2019] PubMed

LINE-1 Evasion of Epigenetic Repression in Humans [Genome Biol. 2019] PubMed

Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family [Genome Res. 2019] PubMed

Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites [Genome Res. 2019] PubMed

Distinct and Collaborative Functions of Yb and Armitage in Transposon-Targeting piRNA Biogenesis [Cell Rep. 2019] PubMed

Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism [MBio. 2019] PubMed

Insertion of a chimeric retrotransposon sequence in mouse Axin1 locus causes metastable kinky tail phenotype [Mob DNA. 2019] PubMed

Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein [Mob DNA. 2019] PubMed

Retrotransposons evolution and impact on lncRNA and protein coding genes in pigs [Mob DNA. 2019] PubMed

A HORT1 retrotransposon insertion in the PeMYB11 promoter causes harlequin/black flowers in Phalaenopsis orchids [Plant Physiol. 2019] PubMed

Islands of retroelements are major components of Drosophila centromeres [PLos Biol. 2019] PubMed

Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies [PLoS Biol. 2019] PubMed

A group II intron-encoded protein interacts with the cellular replicative machinery through the β-sliding clamp [Nucleic Acids Res. 2019] PubMed

RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level [J Vis Exp. 2019] PubMed

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation [Mol Cell. 2019] PubMed

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools [Cold Spring Harb Perspect Biol. 2019] PubMed

A high-quality apple genome assembly reveals the association of a retrotransposon and red fruit colour [Nat Commun. 2019] PubMed

DPPA2 and DPPA4 are necessary to establish a 2C-like state in mouse embryonic stem cells [EMBO Rep. 2019] PubMed

A single-input binary counting module based on serine integrase site-specific recombination [Nucleic Acids Res. 2019] PubMed

The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection [Mol Cell. 2019] PubMed

Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication [Cell 2019] PubMed

Tracking the origin of two genetic components associated with transposable element bursts in domesticated rice [Nat Commun. 2019] PubMed

Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements [Nat Commun. 2019] PubMed

Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals [PLoS Genet. 2019] PubMed

Transposon molecular domestication and the evolution of the RAG recombinase [Nature. 2019] PubMed

Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons allow transcription in distantly related genomes [Mob DNA. 2019] PubMed

Evolution of Mutator transposable elements across eukaryotic diversity [Mob DNA. 2019] PubMed

Spontaneous mutations in maize pollen are frequent in some lines and arise mainly from retrotranspositions and deletions [Proc Natl Acad Sci USA. 2019] PubMed

ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer [Nat Commun. 2019] PubMed

Subtype classification and functional annotation of L1Md retrotransposon promoters [Mob DNA. 2019] PubMed

The Genome of Blue-Capped Cordon-Bleu Uncovers Hidden Diversity of LTR Retrotransposons in Zebra Finch [Genes (Basal). 2019] PubMed

Mouse germ line mutations due to retrotransposon insertions [Mob DNA. 2019] PubMed

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses [Proc Natl Acad Sci USA. 2019] PubMed

Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila [PLoS Genet. 2019] PubMed

The impact of transposable element activity on therapeutically relevant human stem cells [Mob DNA. 2019] PubMed

Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome [Mob DNA. 2019] PubMed

Origins and evolution of CRISPR-Cas systems [Philos Trans R Soc Lond B Biol Sci. 2019] PubMed

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells [Nat Commun. 2019] PubMed

Gorillas have been infected with the HERV-K (HML-2) endogenous retrovirus much more recently than humans and chimpanzees [Proc Natl Acad Sci U S A. 2019] PubMed

Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids [Retrovirology. 2019] PubMed

RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena [Genes Dev. 2019] PubMed

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice [Nat Commun. 2019] PubMed

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools [Cold Spring Harb Perspect Biol. 2019] PubMed

Alu element insertion in the MLH1 exon 6 coding sequence as a mutation predisposing to Lynch syndrome [Hum Mutat 2019] PubMed

L1 drives IFN in senescent cells and promotes age-associated inflammation [Nature 2019] PubMed

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling [Nature 2019] PubMed

CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species. [BMC Genomics 2019] PubMed

Evolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty. [Sci Rep 2019] PubMed

CDI/CDS system-encoding genes of Burkholderia thailandensis are located in a mobile genetic element that defines a new class of transposon. [PLoS Genet. 2019]
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Horizontal transfer of a retrotransposon from the rice planthopper to the genome of an insect DNA virus. [J Virol. 2019]
PubMed

PePIF1, a P-lineage of PIF-like transposable element identified in protocorm-like bodies of Phalaenopsis orchids. [BMC Genomics. 2019]
PubMed

Systematic survey of plant LTR-retrotransposons elucidates phylogenetic relationships of their polyprotein domains and provides a reference for element classification. [Mob DNA. 2019]
PubMed

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes. [Genome Res. 2019] PubMed

Gene duplication and genetic innovation in cereal genomes. [Genome Res. 2019] PubMed

High-Throughput Targeted Repeat Element Bisulfite Sequencing (HT-TREBS). [Methods Mol Biol. 2019] PubMed

Heterogeneity of transposon expression and activation of the repressive network in human fetal germ cells. [Development. 2019] PubMed

Retrophylogenomics in rorquals indicate large ancestral population sizes and a rapid radiation. [Mob DNA. 2019] PubMed

Dynamic methylation of an L1 transduction family during reprogramming and neurodifferentiation. [Mol Cell Biol. 2019] PubMed

A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System. [Mol Cell. 2019] PubMed

Genomic Takeover by Transposable Elements in the Strawberry Poison Frog. [Mol Biol Evol. 2018] PubMed

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks [Nature. 2018] PubMed

High-performance gene expression and knockout tools using sleeping beauty transposon system. [Mob DNA. 2018] PubMed

MITE Tracker: an accurate approach to identify miniature inverted-repeat transposable elements in large genomes. [BMC Bioinformatics. 2018] PubMed

Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. [Nucleic Acids Res. 2018] PubMed

PiggyBac Transposon-Based Insertional Mutagenesis in Mice. [Methods Mol Biol. 2019] PubMed

Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery. [Methods Mol Biol. 2019] PubMed

Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis. [Methods Mol Biol. 2019] PubMed

Transposable element insertions in fission yeast drive adaptation to environmental stress. [Genome Res. 2018] PubMed

Variation in proviral content among human genomes mediated by LTR recombination. [Mob DNA. 2018] PubMed

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis. [Mob DNA. 2018] PubMed

A Robust Transposon-Endogenizing Response from Germline Stem Cells. [Dev Cell. 2018] PubMed

Drosophila small ovary gene is required for transposon silencing and heterochromatin organisation and ensures germline stem cell maintenance and differentiation. [Development. 2018] PubMed

Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma. [BMC Med Genomics. 2018] PubMed

Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. [Proc Natl Acad Sci USA. 2018] PubMed

True Homoplasy of Retrotransposon Insertions in Primates. [Syst Biol. 2018] PubMed

An advanced enrichment method for rare somatic retroelement insertions sequencing. [Mob DNA. 2018] PubMed

TETyper: a bioinformatic pipeline for classifying variation and genetic contexts of transposable elements from short-read whole-genome sequencing data. [Microb Genom. 2018] PubMed

ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses. [Proc Natl Acad Sci USA. 2018] PubMed

Testing the retroelement invasion hypothesis for the emergence of the ancestral eukaryotic cell. [Proc Natl Acad Sci USA. 2018] PubMed

Ten things you should know about transposable elements. [Genome Biol. 2018] PubMed

Bacterial group II introns generate genetic diversity by circularization and trans-splicing from a population of intron-invaded mRNAs. [PLoS Genet. 2018] PubMed

Mobilization of Pack-CACTA transposons in Arabidopsis suggests the mechanism of gene shuffling. [Nucleic Acids Res. 2018] PubMed

Genome-Wide Mapping of Yeast Retrotransposon Integration Target Sites. [Methods Enzymol. 2018] PubMed

NP220 mediates silencing of unintegrated retroviral DNA. [Nature. 2018] PubMed

An Analysis of IS630/Tc1/mariner Transposons in the Genome of a Pacific Oyster, Crassostrea gigas. [J Mol Evol. 2018] PubMed

Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. [Elife. 2018] PubMed

Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. [Nucleic Acids Res. 2018] PubMed 

Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis. [Proc Natl Acad Sci USA. 2018] PubMed

Transposase subunit architecture and its relationship to genome size and the rate of transposition in prokaryotes and eukaryotes. [Nucleic Acids Res. 2018] PubMed

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. [Cell. 2018] PubMed

Serine Integrase attP Binding and Specificity. [J Mol Biol. 2018] PubMed

Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length. [PLoS Biol. 2018] PubMed

Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. [Nucleic Acids Res. 2018] PubMed

Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors. [Proc Natl Acad Sci U S A. 2018] PubMed

Transposons take remote control. [Elife. 2018] PubMed

The PMEL Gene and Merle in the Domestic Dog: A Continuum of Insertion Lengths Leads to a Spectrum of Coat Color Variations in Australian Shepherds and Related Breeds. [Cytogenet Genome Res. 2018] PubMed

Mobile Genetic Elements Associated with Antimicrobial Resistance. [Clin Microbiol Rev. 2018] PubMed

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins. [Mol Neurodegener. 2018] PubMed

HIV-1 Vpr and p21 restrict LINE-1 mobility. [Nucleic Acids Res. 2018] PubMed

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion. [Proc Natl Acad Sci USA. 2018] PubMed

Assessing genome assembly quality using the LTR Assembly Index (LAI). [Nucleic Acids Res. 2018] PubMed

Stress affects the epigenetic marks added by natural transposable element insertions in Drosophila melanogaster. [Sci Rep. 2018] PubMed

Length variations within the Merle retrotransposon of canine PMEL: correlating genotype with phenotype. [Mob DNA. 2018] PubMed

Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells. [Stem Cells Int. 2018] PubMed

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. [Cell. 2018] PubMed

Impact of transposable elements on genome structure and evolution in wheat. [Genome Biol. 2018] PubMed

LINE-ing Up to Influence Splicing [Cell. 2018] Video abstract

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing [Cell. 2018] PubMed

Hijacking Oogenesis Enables Massive Propagation of LINE and Retroviral Transposons [Cell. 2018] PubMed

Impact of non-LTR retrotransposons in the differentiation and evolution of anatomically modern humans. [Mob DNA. 2018] PubMed

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins [Mol Neurodegener. 2018] PubMed

Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers. [Genome Res. 2018] PubMed

Genome-Wide Determination of Gene Essentiality by Transposon Insertion Sequencing in Yeast Pichia pastoris. [Sci Rep. 2018] PubMed

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs. [BMC Genomics. 2018] PubMed

Contrasting Rates of LINE-1 Amplification among New World Primates of the Atelidae Family. [Cytogenet Genome Res. 2018] PubMed

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. [Cell. 2018] PubMed

Drosophila parasitoid wasps bears a distinct DNA transposon profile. [Mob DNA. 2018] PubMed

L1 retrotransposition in the soma: a field jumping ahead. [Mob DNA. 2018] PubMed

A high throughput screen for active human transposable elements. [BMC Genomics. 2018] PubMed

Retrotransposon-induced mosaicism in the neural genome. [Open Biol. 2018] PubMed

TIP60 represses activation of endogenous retroviral elements. [Nucleic Acids Res. 2018] PubMed

Nimble and Ready to Mingle: Transposon Outbursts of Early Development. [Trends Genet. 2018] PubMed

Hijacking Oogenesis Enables Massive Propagation of LINE and Retroviral Transposons. [Cell. 2018] PubMed

The maize W22 genome provides a foundation for functional genomics and transposon biology. [Nat Genet. 2018] PubMed

Transcriptional control and exploitation of an immune-responsive family of plant retrotransposons. [EMBO J. 2018] PubMed

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. [Proc Natl Acad Sci USA. 2018] PubMed

Insect retroelements provide novel insights into the origin of hepatitis B viruses. [Mol Biol Evol. 2018] PubMed

Border collies of the genome: domestication of an autonomous retrovirus-like transposon. [Curr Genet. 2018] PubMed

Tie-Break: Host and Retrotransposons Play tRNA. [Trends Cell Biol. 2018] PubMed

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. [Cell. 2018] PubMed

Convergent evolution of integration site selection upstream of tRNA genes by yeast and amoeba retrotransposons. [Nucleic Acids Res. 2018] PubMed

Transposable elements and gene expression during the evolution of amniotes. [Mob DNA. 2018] PubMed

Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression. [EMBO J. 2018] PubMed

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages. [PLoS Genet. 2018] PubMed

L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution. [Cell Rep. 2018] PubMed

Non-viral therapeutic cell engineering with the Sleeping Beauty transposon system. [Curr Opin Genet Dev. 2018] PubMed

RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition. [EMBO J. 2018] PubMed

Retrotransposon targeting to RNA polymerase III-transcribed genes. [Mob DNA. 2018] PubMed

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis. [Science. 2018] PubMed

Mobilization of retrotransposons as a cause of chromosomal diversification and rapid speciation: the case for the Antarctic teleost genus Trematomus. [BMC Genomics. 2018] PubMed

The case for not masking away repetitive DNA. [Mob DNA. 2018] PubMed

Oocyte Quality Control: Causes, Mechanisms, and Consequences. [Cold Spring Harb Symp Quant Biol. 2018] PubMed

Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross-Talk and a Second Function for Ure2p in Saccharomyces cerevisiae. [Genetics. 2018] PubMed

Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression. [Proc Natl Acad Sci U S A. 2018] PubMed

Contrasted patterns of evolution of the LINE-1 retrotransposon in perissodactyls: the history of a LINE-1 extinction. [Mob DNA. 2018] PubMed

The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. [Mob DNA. 2018] PubMed

Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering. [Nucleic Acids Res. 2018] PubMed

A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. [Mob DNA. 2018] PubMed

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis. [Genome Res. 2018] PubMed

Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes. [Genome Res. 2018] PubMed

Horizontal transfer of retrotransposons between bivalves and other aquatic species of multiple phyla. [Proc Natl Acad Sci USA. 2018] PubMed

A machine learning based framework to identify and classify long terminal repeat retrotransposons. [PLos Comput Biol. 2018] PubMed

Control of yeast retrotransposons mediated through nucleoporin evolution. [PLos Genet. 2018] PubMed

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. [Science. 2018] PubMed

Spliced integrated retrotransposed element (SpIRE) formation in the human genome. [PLoS Biol. 2018] PubMed

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. [PLoS Pathog. 2018]PubMed 

Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology. [PLoS Biol. 2018] PubMed 

The yeast Ty1 retrotransposon requires components of the nuclear pore complex for transcription and genomic integration. [Nucleic Acids Res. 2018] PubMed

Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance. [Cell. 2018] PubMed  

Preferential Ty1 retromobility in mother cells and nonquiescent stationary phase cells is associated with increased concentrations of total Gag or processed Gag and is inhibited by exposure to a high concentration of calcium. [Aging. 2018] PubMed

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p. [Elife. 2018] PubMed 

Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes. [Genome Res. 2018] PubMed

Early life experience drives structural variation of neural genomes in mice. [Science. 2018] PubMed 

Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology. [Curr Opin Genet Dev. 2018] PubMed 

Double insertion of transposable elements provides a substrate for the evolution of satellite DNAs. [Genome Res. 2018] PubMed

Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays. [Mol Cell. 2018] PubMed  

Helraiser intermediates provide insight into the mechanism of eukaryotic replicative transposition. [Nat Commun. 2018] PubMed 

Mammalian transposable elements and their impacts on genome evolution. [Chromosome Res. 2018] PubMed

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation. [Cell. 2018] PubMed

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. [Cell. 2018] PubMed

Sleeping Beauty transposon integrates into non-TA dinucleotides. [Mob DNA. 2018] PubMed

The Birth and Demise of the ISApl1-mcr-1-ISApl1 Composite Transposon: the Vehicle for Transferable Colistin Resistance. [MBio. 2018] PubMed

Comparative genome analysis of 52 fish species suggests differential associations of repetitive elements with their living aquatic environments. [BMC Genomics. 2018] PubMed

The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters. [PLoS Genet. 2018] PubMed

LINE-1 protein localization and functional dynamics during the cell cycle. [Elife. 2018] PubMed

Dissection of affinity captured LINE-1 macromolecular complexes. [Elife. 2018] PubMed

Human transposable elements in Repbase: genomic footprints from fish to humans. [Mob DNA. 2018] PubMed

Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells. [Mob DNA. 2018] PubMed

Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition. [Nucleic Acids Res. 2018] PubMed

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. [Cell. 2018] PubMed

Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons. [Cell. 2018] PubMed

Transposon-derived small RNAs triggered by miR845 mediate genome dosage response in Arabidopsis. [Nat Genet. 2018] PubMed

SETDB1 prevents TET2-dependent activation of IAP retroelements in naïve embryonic stem cells. [Genome Biol. 2018] PubMed

The axolotl genome and the evolution of key tissue formation regulators. [Nature. 2018] PubMed

The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms. [Nature. 2018] PubMed

A novel family of tyrosine integrases encoded by the temperate pleolipovirus SNJ2. [Nucleic Acids Res. 2018] PubMed

Targeted deletion of a 170 kb cluster of LINE1 repeats: implications for regional control. [Genome Res. 2018] PubMed

Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells. [Nature 2018]

Characterization of a functional insertion sequence ISSau2 from Staphylococcus aureus. [Mob DNA. 2018 Jan] PubMed

Rewired RNAi-mediated genome surveillance in house dust mites. [PLoS Genet. 2018] PubMed

Maize Transposable Elements Ac/Ds as Insertion Mutagenesis Tools in Candida albicans.
[G3 (Bethesda). 2018] PubMed

Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase. [Nucleic Acids Res. 2018] PubMed

Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain. [Mob DNA. 2017] PubMed

piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. [Nature. 2017] PubMed

Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.[Nature. 2017] PubMed

piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. [Nature. 2017] PubMed

Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications [Mol Cell. 2017] PubMed

Host factors that promote retrotransposon integration are similar in distantly related eukaryotes. [PLoS Genet. 2017] PubMed

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1. [Proc Natl Acad Sci USA. 2017] PubMed

Transcription coupled repair and biased insertion of human retrotransposon L1 in transcribed genes. [Mob DNA. 2017] PubMed

LINE-1 Retrotransposons in Healthy and Diseased Human Brain. [Dev Neurobiol. 2017] PubMed

Editorial: Mobile Genetic Elements in Cellular Differentiation, Genome Stability, and Cancer. [Front Chem. 2017] PubMed

De-novo emergence of SINE retroposons during the early evolution of passerine birds. [Mob DNA. 2017] PubMed

Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites. [Mob DNA. 2017] PubMed

Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferences. [Mol Microbiol. 2017] PubMed

PIWI-Interacting RNA in Drosophila: Biogenesis, Transposon Regulation, and Beyond. [Chem Rev. 2017] PubMed

ZmCCT9 enhances maize adaptation to higher latitudes. [Proc Natl Acad Sci USA 2017] PubMed

Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering. [Nucleic Acids Res. 2017] PubMed

New reference genome sequences of hot pepper reveal the massive evolution of plant disease-resistance genes by retroduplication. [Genome Biol. 2017] PubMed

TGTT and AACA: two transcriptionally active LTR retrotransposon subfamilies with a specific LTR structure and horizontal transfer in four Rosaceae species. [Mob DNA. 2017] PubMed

High-frequency recombination between members of an LTR retrotransposon family during transposition bursts. [Nat Commun. 2017] PubMed

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [Proc Natl Acad Sci U S A. 2017] PubMed

tRNA-derived small RNAs: New players in genome protection against retrotransposons. [RNA Biol. 2017 ] PubMed

Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. [Mol Cell. 2017] PubMed

Globular domain structure and function of restriction-like-endonuclease LINEs: similarities to eukaryotic splicing factor Prp8. [Mob DNA. 2017] PubMed

Genome sequence of the progenitor of the wheat D genome Aegilops tauschii. [Nature. 2017]

Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey. [Nucleic Acids Res. 2017] PubMed

Mobile genetic elements and evolution of CRISPR-Cas systems: all the way there and back. [Genome Biol Evol. 2017] PubMed

Retrotransposons: Stowaways in the Primordial Germline. [Curr Biol. 2017] PubMed

Genetic Drift, Not Life History or RNAi, Determine Long-Term Evolution of Transposable Elements. [Genome Biol Evol. 2017] PubMed

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. [PLoS Genet. 2017] PubMed

Viral communities of the human gut: metagenomic analysis of composition and dynamics. [Mob DNA. 2017] PubMed

Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells. [Nucleic Acids Res. 2017] PubMed

A single active site in the mariner transposase cleaves DNA strands of opposite polarity. [Nucleic Acids Res. 2017] PubMed

Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae. [Genetics. 2017] PubMed

Improved maize reference genome with single-molecule technologies. [Nature. 2017] PubMed

Retrotransposon Domestication and Control in Dictyostelium discoideum. [Front Microbiol. 2017] PubMed

SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers. [Nucleic Acids Res. 2017] PubMed

A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement. [Nucleic Acids Res. 2017] PubMed

Horizontal transfer of non-LTR retrotransposons from arthropods to flowering plants. [Mol Biol Evol. 2017] PubMed

CLIFinder: Identification of LINE-1 Chimeric Transcripts in RNA-seq data. [Bioinformatics. 2017] PubMed

Transposons As Tools for Functional Genomics in Vertebrate Models. [Trends Genet. 2017] PubMed

How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration. [Nature. 2017] PubMed

The TREX1 Dinosaur Bites the Brain through the LINE. [Cell Stem Cell. 2017] PubMed

Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer. [Philos Trans R Soc Lond B Biol Sci. 2017] PubMed

Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. [Curr Biol. 2017] PubMed

Gene Therapy with the Sleeping Beauty Transposon System. [Trends Genet. 2017] PubMed

Alu Insertion Polymorphisms as Evidence for Population Structure in Baboons. [Genome Biol Evol. 2017] PubMed

A fine LINE-1 in mouse embryonic chromatin regulation. [Nat Genet. 2017] PubMed

Integrative and conjugative elements and their hosts: composition, distribution and organization. [Nucleic Acids Res. 2017] PubMed

Complete fusion of a transposon and herpesvirus created the Teratorn mobile element in medaka fish. [Nat Commun. 2017] PubMed

Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals. [Genome Biol Evol. 2017] PubMed

A fine LINE-1 in mouse embryonic chromatin regulation. [Nat Genet. 2017] PubMed

Barbara McClintock's Final Years as Nobelist and Mentor: A Memoir. [Cell. 2017] PubMed

Mobile DNA in Health and Disease. [N Engl J Med. 2017 July] PubMed

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses. [PLoS Genet. 2017 July] PubMed

Comprehensive arrayed transposon mutant library of Klebsiella pneumoniae outbreak strain KPNIH1. [J Bacteriol. 2017 July] PubMed

Discovery of rare, diagnostic AluYb8/9 elements in diverse human populations. [Mob DNA. 2017 July] PubMed

Recruitment of CRISPR-Cas systems by Tn7-like transposons. [Proc Natl Acad Sci USA. 2017 Aug] PubMed

Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. [Elife. 2017 Aug] PubMed

Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. [Cell Stem Cell. 2017 Aug] PubMed

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism. [Nat Struct Mol Biol. 2017 June] PubMed

L1 Mosaicism in Mammals: Extent, Effects, and Evolution. [Trends Genet. 2017 Aug] PubMed

Environmentally triggered genomic plasticity and capsular polysaccharide formation are involved in increased ethanol and acetic acid tolerance in Kozakia baliensis NBRC 16680. [BMC Microbiol. 2017 Aug] PubMed

A genome-wide transcriptome and translatome analysis of Arabidopsis transposons identifies a unique and conserved genome expression strategy for Ty1/Copia retroelements. [Genome Res. 2017 Aug] PubMed

HISTONE DEACETYLASE6 Acts in Concert with Histone Methyltransferases SUVH4, SUVH5, and SUVH6 to Regulate Transposon Silencing. [Plant Cell. 2017 Aug] PubMed

Developmental Restriction of Retrotransposition Activated in Arabidopsis by Environmental Stress. [Genetics. 2017 Aug] PubMed

Human Retrotransposon Insertion Polymorphisms Are Associated with Health and Disease via Gene Regulatory Phenotypes. [Front Microbiol. 2017 Aug] PubMed

Transposon Sequencing Uncovers an Essential Regulatory Function of Phosphoribulokinase for Methylotrophy. [Curr Biol. 2017 Aug] PubMed

Mobile Group II Introns as Ancestral Eukaryotic Elements. [Trends Genet. 2017 Aug] PubMed

Landscape and variation of novel retroduplications in 26 human populations. [PLoS Comput Biol. 2017 June] PubMed

MGEScan: a Galaxy-based system for identifying retrotransposons in genomes. [Bioinformatics 2016 Aug] PubMed

Transposon Insertion Site Sequencing for Synthetic Lethal Screening. [Methods Mol Biol. 2017 Aug] PubMed

LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. [Nat. Genet. 2017 Aug] PubMed

rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. [PLoS Genet. 2017 Aug] PubMed

TnseqDiff: identification of conditionally essential genes in transposon sequencing studies. [BMC Bioinformatics. 2017 July] PubMed

Fusion of a superfamily 1 helicase and an inactivated DNA polymerase is a signature of common evolutionary history of Polintons, polinton-like viruses, Tlr1 transposons and transpovirons. [Virus Evol. 2016 June] PubMed

Structures of the CRISPR genome integration complex. [Science. 2017 July] PubMed

Resolving the prevalence of somatic transposition in Drosophila. [Elife. 2017 July] PubMed

Drosophila: Retrotransposons Making up Telomeres. [Viruses. 2017 July] PubMed

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses. [Genetics. 2017 July] PubMed

Canalization by Selection of De Novo-Induced Mutations. [Genetics. 2017 June] PubMed

Giant reverse transcriptase-encoding transposable elements at telomeres. [Mol Biol Evol. 2017 May] PubMed

The Role of Somatic L1 Retrotransposition in Human Cancers. [Viruses. 2017 May] PubMed

Analysis of LINE-1 Elements in DNA from Postmortem Brains of Individuals with Schizophrenia. [Neuropsychopharmacology. 2017 June] PubMed

Making serine integrases work for us. [Curr Opin Microbiol. 2017 June] PubMed

Retrotransposons are specified as DNA replication origins in the gene-poor regions of Arabidopsis heterochromatin. [Nucleic Acids Res. 2017 June] PubMed

Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements. [PLoS Pathog. 2017 June] PubMed

Intact piRNA pathway prevents L1 mobilization in male meiosis. [Proc Natl Acad Sci USA. 2017 June] PubMed

Transposable elements in cancer. [Epub 2017 June] PubMed

DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation. [Proc Natl Acad Sci USA. 2017 June] PubMed

Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells. [Nucleic Acids Res. 2017 June] PubMed

LTR-Retrotransposon Control by tRNA-Derived Small RNAs. [J Cell Sci. 2017 June] PubMed

Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain. [BMC Biol. 2017 June] PubMed

Retroviral intasomes arising. [Curr Opin Struct Biol. 2017 Apr] PubMed

Piwi Is Required during Drosophila Embryogenesis to License Dual-Strand piRNA Clusters for Transposon Repression in Adult Ovaries. [Mol Cell. 2017 Apr] PubMed

Evolutionary history of LTR-retrotransposons among 20 Drosophila species. [Mob DNA. 2017 Apr] PubMed

Structural variants caused by Alu insertions are associated with risks for many human diseases. [Proc Natl Acad Sci U S A. 2017 May] PubMed

Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery. [Curr Opin Microbiol. 2017 May] PubMed

Heritable L1 retrotransposition in the mouse primordial germline and early embryo. [Genome Res. 2017 May] PubMed

Transposition of Mutator-like transposable elements (MULEs) resembles hAT and Transib elements and V(D)J recombination. [Nucleic Acids Res. 2017 May] PubMed

Functional mapping of yeast genomes by saturated transposition. [Elife. 2017 May] PubMed

Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration. [Mob DNA. 2017 May] PubMed

MAGenTA; a Galaxy implemented tool for complete Tn-Seq analysis and data visualization. [Bioinformatics. 2017 May] PubMed

Integration site selection by retroviruses and transposable elements in eukaryotes. [Nat Rev Genet. 2017 May] PubMed

A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568. [Science. 2017 May] PubMed

Coiled-coil interactions mediate serine integrase directionality. [Nucleic Acids Res. 2017 May] PubMed

Characterization of autonomous families of Tc1/mariner transposons in neoteleost genomes. [Mar Genomics. 2017 May] PubMed

Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea. [Nat Microbiol. 2017 Apr] PubMed

Structure of Ty1 Internally Initiated RNA Influences Restriction Factor Expression. [Viruses. 2017 Apr] PubMed

Integration site selection by retroviruses and transposable elements in eukaryotes. [Nature. 2017 March] PubMed

LoRTE: Detecting transposon-induced genomic variants using low coverage PacBio long read sequences. [Mob DNA. 2017 Apr] PubMed

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI). [Science. 2017 Apr] PubMed

LTRtype, an Efficient Tool to Characterize Structurally Complex LTR Retrotransposons and Nested Insertions on Genomes. [Front Plant Sci. 2017 Apr] PubMed

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. [Nucleic Acids Res. 2017 Apr] PubMed

Aubergine Controls Germline Stem Cell Self-Renewal and Progeny Differentiation via Distinct Mechanisms. [Dev Cell. 2017 Apr] PubMed

Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA. [Viruses. 2017 Apr] PubMed

Natural variation of piRNA expression affects immunity to transposable elements. [PLoS Genet. 2017 Apr] PubMed

Insertion and deletion polymorphisms of the ancient AluS family in the human genome. [Mob DNA. 2017 Apr] PubMed

LINE Insertion Polymorphisms are Abundant but at Low Frequencies across Populations of Anolis carolinensis. [Front Genet. 2017 Apr] PubMed

Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export. [Nucleic Acids Res. 2017 Mar] PubMed

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion. [Nucleic Acids Res. 2017 Mar] PubMed

Inhibition of human endogenous retrovirus-K by antiretroviral drugs. [Retrovirology. 2017 Mar] PubMed

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. [Nature. 2017 Mar] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Proc Natl Acad Sci U S A. 2017 Mar] PubMed 

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. [J Cell Sci. 2017 Mar] PubMed 

Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3. [Viruses. 2017 Mar] PubMed

Convergence of retrotransposons in oomycetes and plants. [Mob DNA. 2017 Mar] PubMed

Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. [Genetics. 2017 Mar] PubMed

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. [PLoS Genet. 2017 Mar] PubMed

Speciation network in Laurasiatheria: retrophylogenomic signals. [Genome Res. 2017 Mar] PubMed

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. [Nat Genet. 2017 Mar] PubMed

A transposon-derived small RNA regulates gene expression in Salmonella Typhimurium. [Nucleic Acids Res. 2017 Feb] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Nucleic Acids Res. 2017 Feb] PubMed

A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. [Sci Rep. 2017 Feb] PubMed

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal. [E Life. 2017 Feb] PubMed

The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. [Clin Chem. 2017 Feb] PubMed

Transposition of the bamboo Mariner-like element Ppmar1 in yeast. [Mol Phylogenet Evol. 2017 Feb] PubMed

Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis. [J Biol Chem. 2017 Feb] PubMed

Sequencing the extrachromosomal circular mobilome reveals retrotransposon activity in plants. [PLoS Genet. 2017 Feb 17] PubMed

ALUternative Regulation for Gene Expression. [Trends Cell Biol. 2017 Feb] PubMed

Transposable Element Bm1645 is a Source of BmAGO2-associated Small RNAs that affect its expression in Bombyx mori. [BMC Genomics. 2017 Feb] PubMed

Conserved expression of transposon-derived non-coding transcripts in primate stem cells. [BMC Genomics. 2017 Feb] PubMed

Single genome retrieval of context-dependent variability in mutation rates for human germline. [BMC Genomics. 2017 Jan] PubMed

Hsp90 and physiological stress are linked to autonomous transposon mobility and heritable genetic change in nematodes. [Genome Biol Evol. 2017 Jan] PubMed

An optimized, broadly applicable piggyBac transposon induction system. [Nucleic Acids Res. 2017 Jan] PubMed

Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition. [Genetics. 2017 Jan] PubMed

The FACT complex promotes avian leukosis virus DNA integration. [J Virol. 2017 Jan] PubMed

G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. [Nat Struct Mol Biol. 2017 Jan] PubMed

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. [Nucleic Acids Res. 2017 Jan] PubMed

Transposase-Mediated Excision, Conjugative Transfer and Diversity of ICE6013 in Staphylococcus aureus. [J Bacteriol. 2017 Jan] PubMed

Protein splicing of a recombinase intein induced by ssDNA and DNA damage. [Genes Dev. 2016 Dec] PubMed

Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. [Genes Dev. 2016 Dec] PubMed

A supramolecular assembly mediates lentiviral DNA integration. [Science. 2017 Jan] PubMed

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. [Science. 2017 Jan] PubMed

Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis. [Appl Environ Microbiol. 2017 Jan] PubMed

piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

GB3.0: a platform for plant bio-design that connects functional DNA elements with associated biological data. [Nucleic Acids Res. 2017 Jan] PubMed 

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition. [Genetics. 2017 Jan] PubMed

TET enzymes: double agents in the transposable element-host genome conflict. [Genome Biol. 2016 Dec] PubMed

Endogenous retroviral promoter exaptation in human cancer. [Mob DNA. 2016 Dec] PubMed

Incidental mutations occur frequently during transposon mutagenesis. [FEMS Microbiol Lett. 2016 Dec] PubMed

Paralog-Specific Functions of RPL7A and RPL7B Mediated by Ribosomal Protein or snoRNA Dosage in Saccharomyces cerevisiae. [G3 (Bethesda). 2016 Dec] PubMed

DNA binding specificities of Escherichia coli Cas1-Cas2 integrase drive its recruitment at the CRISPR locus. [Nucleic Acids Res. 2016 Dec] PubMed

Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion. [Nucleic Acids Res. 2016 Dec] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Multiple Transcriptional and Post-Transcriptional Pathways Collaborate To Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast. [Genetics. 2016 Dec] PubMed

Non-canonical Helitrons in Fusarium oxysporum. [Mob DNA. 2016 Dec] PubMed

Destabilization of B2 RNA by EZH2 Activates the Stress Response. [Cell. 2016 Dec] PubMed

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells. [Genome Res. 2017 Jan] PubMed

Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition. [Nucleic Acids Res. 2017 Jan] PubMed

L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes. [Nucleic Acids Res. 2017 Jan] PubMed

Telomeric Retrotransposon HeT-A Contains a Bidirectional Promoter that Initiates Divergent Transcription of piRNA Precursors in Drosophila Germline. [J Mol Biol. 2016 Dec] PubMed

Engineered LINE-1 retrotransposition in non-dividing human neurons. [Genome Res. 2016 Dec] PubMed

New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination. [FEBS J. 2016 Dec] PubMed

A map of mobile DNA insertions in the NCI-60 human cancer cell panel. [Mob DNA. 2016 Oct] PubMed

MTV, an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in Drosophila. [PLoS Genet. Nov 2016] PubMed

Retroviruses integrate into a shared, non-palindromic DNA motif. Nat Microbiol. 2016 Nov] PubMed 

Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme. [Mob DNA. 2016 Nov] PubMed

Somatic retrotransposition is infrequent in glioblastomas. [Mob DNA. 2016 Nov] PubMed

Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression. [Proc Natl Acad Sci U S A. 2016 Nov] PubMed

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity. [Science. 2016 Nov] PubMed

Numerous small hammerhead ribozyme variants associated with Penelope-like retrotransposons cleave RNA as dimers. [RNA Biol. 2016 Nov] PubMed 

The impact of transposable elements on mammalian development. [Development. 2016 Nov] PubMed

Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder. [Sci Rep. 2016 Nov] PubMed

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences. [Mol Cell. 2016 Dec] PubMed

Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition. [Mob DNA. 2016 Nov] PubMed

Patterns of Transposable Element Expression and Insertion in Cancer. [Front Mol Biosci. 2016 Nov] PubMed

Temporal self-regulation of transposition through host-independent transposase rodlet formation. [Nucleic Acids Res. 2017 Jan] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Close ecological relationship among species facilitated horizontal transfer of retrotransposons. [BMC Evol Biol. Oct 2016] PubMed

In vivo continuous evolution of genes and pathways in yeast. [Nat Commun. Oct 2016] PubMed

Mechanism for DNA transposons to generate introns on genomic scales. [Nature. Oct 2016] PubMed

The Functionality of Minimal PiggyBac Transposons in Mammalian Cells. [Mol Ther Nucleic Acids. Oct 2016] PubMed

Autonomous replication of the conjugative transposon Tn916. [J Bacteriol. Oct 2016] PubMed

Sleeping Beauty transposition: from biology to applications. [Crit Rev Biochem Mol Biol. Oct 2016] PubMed

LINEs between species: Evolutionary dynamics of LINE-1 retrotransposons across the eukaryotic tree of life. [Genome Biol Evol. Oct 2016] PubMed

Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis. [Methods Mol Biol. 2017] PubMed

Assembly and transfer of tripartite integrative and conjugative genetic elements. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Retrotransposon-mediated aluminum tolerance through enhanced expression of the citrate transporter OsFRDL4. [Plant Physiol. Oct 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

Profiling Transposable Elements and Their Epigenetic Effects in Non-model Species. [Methods Mol Biol. 2017] PubMed

Genomics and the evolution of antibiotic resistance. [Ann N Y Acad Sci. Oct 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

p53 in the game of transposons. [Bioessays. Nov 2016] PubMed

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Assembly and transfer of tripartite integrative and conjugative genetic elements. [Proc Natl Acad Sci U S A. 2016 Oct] PubMed

The Evolution of Line-1 in Vertebrates. [Genome Biol Evol. Oct 2016] PubMed

Drug resistant integrase mutants cause aberrant HIV integrations. [Retrovirology. Sep 2016] PubMed

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Convergent evolution of tRNA gene targeting preferences in compact genomes. [Mob DNA. Aug 2016] PubMed

Protecting genome integrity during CRISPR immune adaptation. [Nat Struct Mol Biol. Oct 2016] PubMed

Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity. [PLoS One. Sep 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

The flow of the gibbon LAVA element is facilitated by the LINE-1 retrotransposition machinery. [Genome Biol Evol. Sep 2016] PubMed

p53 in the game of transposons. [Bioessays. Sep 2016] PubMed

Helitron-like transposons contributed to the mating system transition from out-crossing to self-fertilizing in polyploid Brassica napus L. [Sci Rep. Sep 2016] PubMed

Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systems.[Nucleic Acids Res. Sep 2016] PubMed

ADAR1 restricts LINE-1 retrotransposition. [Nucleic Acids Res. Sep 2016] PubMed

TRT, a Vertebrate and Protozoan Tc1-Like Transposon: Current Activity and Horizontal Transfer. [Genome Biol Evol. Oct 2016] PubMed

Restricting retrotransposons: a review. [Mob DNA. Aug 2016] PubMed

Piwi Modulates Chromatin Accessibility by Regulating Multiple Factors Including Histone H1 to Repress Transposons. [Mol Cell. Aug 2016] PubMed

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis. [Cell. Aug 2016] PubMed

Direct interrogation of the role of H3K9 in metazoan heterochromatin function. [Genes Dev. Aug 2016] PubMed

Production of Small Non-coding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster. [Genetics. Aug 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites. [Nucleic Acids Res. Aug 2016] PubMed

The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes. [Genome Biol Evol. Sep 2016] PubMed

Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome. [Mob DNA. Jul 2016] PubMed

Genome-wide characterization of non-reference transposons in crops suggests non-random insertion. [BMC Genomics. Aug 2016] PubMed

Identification of polymorphic SVA retrotransposons using a mobile element scanning method for SVA (ME-Scan-SVA). [Mob DNA. Jul 2016] PubMed

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. [Nat Biotechnol. Sep 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. June 2016] PubMed

Experimental single-strain mobilomics reveals events that shape pathogen emergence. [Nucleic Acids Res. July 2016] PubMed

Nuclear Noncoding RNAs and Genome Stability. [Mol Cell. July 2016] PubMed

Group II Intron Self-Splicing. [Annu Rev Biophys. July 2016] PubMed

The mechanism of ϕC31 integrase directionality: experimental analysis and computational modelling. [Nucleic Acids Res. July 2016] PubMed

CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. [EMBO Rep. July 2016] PubMed

Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3. [Viruses. July 2016] PubMed

APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity. [PLoS One. July 2016] PubMed

Virus-like attachment sites as structural landmarks of plants retrotransposons. [Mob DNA. July 2016] PubMed

A pair of transposon-derived proteins regulate active DNA demethylation in Arabidopsis. [EMBO J. July 2016] PubMed

Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma. [Proc Natl Acad Sci USA. May 2016] PubMed

Methods for accurate quantification of LTR-retrotransposon copy number using short-read sequence data: a case study in Sorghum. [Mol Genet Genomics. June 2016] PubMed

Transposable Elements versus the Fungal Genome: Impact on Whole-Genome Architecture and Transcriptional Profiles. [PLoS Genet. June 2016] PubMed

Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination. [Cell. June 2016] PubMed

PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice. [Sci Rep. June 2016] PubMed

Repetitive element hypermethylation in multiple sclerosis patients. [BMC Genet. June 2016] PubMed

CRISPR Outsourcing: Commissioning IHF for Site-Specific Integration of Foreign DNA at the CRISPR Array. [Mol Cell. June 2016] PubMed

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma. [Hum Mutat. June 2016] PubMed

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen. [Genome Res. June 2016] PubMed

Retrozymes are a unique family of non-autonomous retrotransposons with hammerhead ribozymes that propagate in plants through circular RNAs. [Genome Biol. June 2016] PubMed

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization. [Genetics. June 2016] PubMed

Analysis of tandem gene copies in maize chromosomal regions reconstructed from long sequence reads. [Proc Natl Acad Sci USA. June 2016] PubMed

Evidence of G.O.D.'s Miracle: Unearthing a RAG Transposon. [Cell. June 2016] PubMed

Structure of a group II intron in complex with its reverse transcriptase. [Nat Struct Mol Biol. May 2016] PubMed

Genomic analysis of mouse VL30 retrotransposons. [Mob DNA. May 2016] PubMed

Roles for retrotransposon insertions in human disease. [Mob DNA. May 2016] PubMed

A bend, flip and trap mechanism for transposon integration. [eLife. May 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. Jun 2016] PubMed

Quantitative Insertion-site Sequencing (QIseq) for high throughput phenotyping of transposon mutants. [Genome Res. May 2016] PubMed

Next-generation sequencing-based detection of germline L1-mediated transductions. [BMC Genomics. May 2016] PubMed

DjPiwiB: A Rich Nuclear Inheritance for Descendants of Planarian Stem Cells. [Dev Cell. May 2016] PubMed

Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian. [Dev Cell. May 2016] PubMed

DNA Transposition at Work. [Chem Rev. May 2016] PubMed

Exploration of the Drosophila buzzatii transposable element content suggests underestimation of repeats in Drosophila genomes. [BMC Genomics. May 2016] PubMed

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen. [BMC Med Genomics. Apr 2016] PubMed

Alternative Computational Analysis Shows No Evidence for Nucleosome Enrichment at Repetitive Sequences in Mammalian Spermatozoa. [Dev Cell. Apr 2016] PubMed

Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. [Aging Cell. Apr 2016] PubMed

Alu SINE analyses of 3,000-year-old human skeletal remains: a pilot study. [Mob DNA. Apr 2016] PubMed

The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations. [Mob DNA. Apr 2016] PubMed

LINE-1-like retrotransposons contribute to RNA-based gene duplication in dicots. [Sci Rep. Apr 2016] PubMed

Brujita Integrase: A simple, arm-less, directionless, and promiscuous tyrosine integrase system. [J Mol Biol. Apr 2016] PubMed

Identification and analysis of integrons and cassette arrays in bacterial genomes. [Nucleic Acids Res. Apr 2016] PubMed

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes. [Nat Commun. Mar 2016] PubMed

GENETICS. A copy-and-paste gene regulatory network. [Science. 2016 Mar] PubMed

Regulatory evolution of innate immunity through co-option of endogenous retroviruses.  [Science. Mar 2016] PubMed

Read count-based method for high-throughput allelic genotyping of transposable elements and structural variants. [BMC Genomics. Jul 2015] PubMed

Both exact target site sequence and long poly(A) tail are required for precise insertion of the 18S rDNA-specific non-long terminal repeat retrotransposon R7Ag. [Mol Cell Biol. Mar 2016] PubMed

Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. [Proc Natl Acad Sci U S A. Mar 2016] PubMed

Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci. [Elife. Mar 2016] PubMed

Multitasking of the piRNA Silencing Machinery: Targeting Transposable Elements and Foreign Genes in the Bdelloid Rotifer Adineta vaga. [Genetics. Mar 2016] PubMed

Immune responses to endogenous retroelements: taking the bad with the good. [Nat Rev Immunol. Mar 2016] PubMed

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering. [Nat Commun. Mar 2016] PubMed

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites. [J Vis Exp. Mar 2016] PubMed

Transposon Calling Cards. [Cold Spring Harb Protoc. Feb 2016] PubMed

Genome ARTIST: a robust, high-accuracy aligner tool for mapping transposon insertions and self-insertions. [Mob DNA. Feb 2016] PubMed

How retrotransposons shape genome regulation.[Curr Opin Genet Dev. Feb 2016] PubMed

Group II introns: versatile ribozymes and retroelements. [Wiley Interdiscip Rev RNA. Feb 2016]. PubMed

Crystal structure of the Rous sarcoma virus intasome. [Nature. Feb 2016] PubMed

Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. [Nature. Feb 2016] PubMed

Transposons and Retrotransposons. [Methods in Molecular Biology. Volume 1400 2016] Springer

Biochemical Characterization of Kat1: a Domesticated hAT-Transposase that Induces DNA Hairpin Formation and MAT-Switching. [Sci Rep. Feb 2016] PubMed

Regulating retrotransposon activity through the use of alternative transcription start sites. [EMBO Rep. Feb 2016] PubMed

Resolving rates of mutation in the brain using single-neuron genomics. [Elife. Feb 2016] PubMed

Retrotransposons as regulators of gene expression. [Science. Feb 2016] PubMed

High-Throughput Genetic Screens Identify a Large and Diverse Collection of New Sporulation Genes in Bacillus subtilis. [PLoS Biol. Jan 2016] PubMed

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. [Nat Commun. Jan 2016] PubMed

Transposable element detection from whole genome sequence data. [Mob DNA. Dec 2015] PubMed

Genome-Wide Profiling Reveals Remarkable Parallels Between Insertion Site Selcetion Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4+ T Cells. [Mol Ther. Jan 2016] PubMed

Recent mobility of casposons, self-synthesizing transposons at the origin of the CRISPR-Cas immunity. [Genome Biol Evol. Jan 2016] PubMed

Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks. [Cold Spring Harb Symp Quant Biol. Jan 2016] PubMed

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins. [Cell. Jan 2016] PubMed

Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance. [Front Genet. Jan 2016] PubMed

Ty1-Integrase interacts with RNA Polymerase III specific subcomplexes to promote insertion of Ty1 elements upstream of Pol III-transcribed genes. [J Biol Chem. Jan 2016] PubMed

The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries. [J.Bioinformatics Jan 2016] PubMed

Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha [Mob DNA. Jan 2016] PubMed

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. [Elife. Jan 2016] PubMed

Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline. [Curr Opin Genet Dev. Jan 2016] PubMed

Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. [G3 (Bethesda). Jan 2016] PubMed

Systematic identification of factors for provirus silencing in embryonic stem cells. [Cell. Sep 2015] PubMed

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. [PLoS Genet. Dec 2015] PubMed

Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation. [Mol Cell. Dec 2015] PubMed

Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome. [Mol Cell. Dec 2015] PubMed

A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces. [Curr Genet. Dec 2015] PubMed

Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. [Mob DNA. Dec 2015] PubMed

Comprehensive ex vivo transposon mutagenesis identifies genes that promote growth factor independence and leukemogenesis. [Cancer Res. Dec 2015] PubMed

Conservative site-specific and single-copy transgenesis in human LINE-1 elements. [Nucleic Acids Res. Dec 2015] PubMed

VHICA, a new method to discriminate between vertical and horizontal transposon transfer: application to the mariner family within Drosophila. [Mol Biol Evol. Dec 2015] PubMed

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. [PLoS Pathog. Dec 2015] PubMed

piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts. [Nucleic Acids Res. Dec 2015] PubMed

p53 genes function to restrain mobile elements. [Genes Dev. Dec 2015] PubMed

The making of a genomic parasite - the Mothra family sheds light on the evolution of Helitrons in plants. [Mob DNA. Dec 2015] PubMed

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. [Science. Dec 2015] PubMed

ISC, a novel group of bacterial and archaeal DNA transposons that encode Cas9 homologs. [J Bacteriol. Dec 2015] PubMed

A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition [Mol Cell. Nov 2015] PubMed

Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation [Mol Cell. Nov 2015] PubMed

The casposon-encoded Cas1 protein from Aciduliprofundum boonei is a DNA integrase that generates target site duplications [NAR. Nov 2015] PubMed

Inference of Transposable Element Ancestry [PLOS Genetics. Nov 2015] PubMed

Unique transposon landscapes are pervasive across Drosophila melanogaster genomes [NAR. Nov 2015] PubMed

Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages [PLoS Pathog. Nov 2015] PubMed

RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens [Genome Res. Nov 2015] PubMed

DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes [Mol Biol Evol. Nov 2015] PubMed

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons [PNAS. Nov 2015] PubMed

Response of transposable elements to environmental stressors [Mutat Res Rev Mutat Res. Jul-Sep 2015] PubMed

Antisense Transcription of Retrotransposons in Drosophila: The Origin of Endogenous Small Interfering RNA Precursors [Genetics. Nov 2015] PubMed

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse [PLoS Genet. Oct 2015] PubMed

Holocentromeres in Rhynchospora are associated with genome-wide centromere-specific repeat arrays interspersed among euchromatin [PNAS. Nov 2015] PubMed

Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity [Cell. Oct 2015] PubMed

Transposon sequencing: methods and expanding applications [Appl Microbiol Biotechnol. Oct 2015] PubMed

Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution [BMC Genomics. Oct 2015] PubMed

Tools for Targeted Genome Engineering of Established Drosophila Cell Lines [Genetics. Oct 2015] PubMed

Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus [Genetics. Oct 2015] PubMed

The Ty1 Retrotransposon Restriction Factor p22 Targets Gag [PLoS Genet. Oct 2015] PubMed

Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides [Science. Oct 2015] PubMed

Arrested replication forks guide retrotransposon integration [Science. Sep 2015] PubMed

Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes [PLoS Genet. Sep 2015] PubMed

Genomic DNA transposition induced by human PGBD5 [Elife. Sep 2015] PubMed

Profiling the RNA editomes of wild-type C. elegans and ADAR mutants [Genome Res. Jan 2015] PubMed

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression [Science. Oct 2015] PubMed

Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians [PLoS Genet. Sep 2015] PubMed

TE-Tracker: systematic identification of transposition events through whole-genome resequencing [BMC Bioinformatics. Nov 2014] PubMed

Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest [Cell. Sep 2015] PubMed

Conformational toggling controls target site choice for the heteromeric transposase element Tn7 [Nucleic Acids Res. Sep 2015] PubMed

Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe [Genetics. Sep 2015] PubMed

Loss of Karma transposon methylation underlies the mantled somaclonal variant of oil palm [Nature. Sep 2015] PubMed

miR-128 represses L1 retrotransposition by binding directly to L1 RNA [Nat Struct Mol Biol. Oct 2015] PubMed

Sequence Analysis and Characterization of Active Human Alu subfamilies Based on the 1000 Genomes Pilot Project [Genome Biol Evol. Aug 2015] PubMed

Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability [DNA Repair Aug 2015] PubMed

Organization and evolution of transposable elements along the bread wheat chromosome 3B [Genome Biology Dec 2014] PubMed

Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions [Genome Biology Dec 2014] PubMed

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma [PNAS Sep 2015] PubMed

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition [Elife. Aug 2015] PubMed

An Atypical AAA+ ATPase Assembly Controls Efficient Transposition through DNA Remodeling and Transposase Recruitment [Cell. Aug 2015] PubMed

Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation [PLoS Genet. Aug 2015] PubMed

piRNAs Are Associated with Diverse Transgenerational Effects on Gene and Transposon Expression in a Hybrid Dysgenic Syndrome of D. virilis [PLoS Genet. Aug 2015] PubMed

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma [Nature Med. Sep 2015] PubMed

MIR retrotransposon sequences provide insulators to the human genome [PNAS. Jul 2015] PubMed

Tn-seq of Caulobacter crescentus under uranium stress reveals genes essential for detoxification and stress tolerance [J Bacteriol. Jul 2015] PubMed

LINE-1 Retroelements Get ZAPped! [PLoS Genet. Jul 2015] PubMed

ZmMBD101 is a DNA binding protein that maintains Mutator elements chromatin in a repressive state in maize [Plant Cell Environ. Jul 2015] PubMed

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation [PLoS Genet. Jul 2015] PubMed

Repbase Update, a database of repetitive elements in eukaryotic genomes [Mobile DNA. Jun 2015] PubMed

The diversification of PHIS transposon superfamily in eukaryotes [Mobile DNA. Jun 2015] PubMed

Distinct sets of PIWI proteins produce arbovirus and transposon-derived piRNAs in Aedes aegypti mosquito cells [Nucleic Acids Res. Jun 2015] PubMed

Structural basis for retroviral integration into nucleosomes [Nature. Jul 2015] PubMed

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery [Curr Opin Genet Dev. Feb 2015] PubMed

A Transposable Element within the Non-canonical Telomerase RNA of Arabidopsis thaliana Telomerase in Response to DNA Damage [PLoS Genet. Jun 2015] PubMed

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination [Genes Dev. Jun 2015] PubMed

The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline [EMBO Rep. Jun 2015] PubMed

Evolution of group II introns [Mobile DNA. Apr 2015] PubMed

N(6)-methyladenine DNA modification in Drosophila [Cell. May 2015] PubMed

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition [PLoS Genet. May 2015] PubMed

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells [Nature. May 2015] PubMed

Rapid quantification of mutant fitness in diverse bacteria by sequencing randomly bar-coded transposons [MBio. May 2015] PubMed

Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production [Science. May 2015] PubMed

Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis [Science. May 2015] PubMed

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes [Sci Rep. May 2015] PubMed

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis [Nat Genet. May 2015] PubMed

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites [Genome Res. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals [Genome Biology. May 2015] PubMed

Mosaic genome of endobacteria in arbuscular mycorrhizal fungi: Transkingdom gene transfer in an ancient mycoplasma-fungus association [PNAS. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses [Genes Dev. Mar 2015] PubMed

Evolution of adaptive immunity from transposable elements combined with innate immune systems [Nat Rev Genet. Mar 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma [Nat Genet. May 2015] PubMed

Phosphorylation of ORF1p is required for L1 retrotransposition [PNAS. Apr 2015] PubMed

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells [Nature. Jun 2015] PubMed

Mobile DNA welcomes new Editors-in-Chief, Marlene Belfort and Haig Kazazian - a BioMed Central blog biomedcentral.com

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage [Biol Trace Elem Res. Mar 2015] PubMed