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Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila [PLoS Genet. 2019] PubMed

The impact of transposable element activity on therapeutically relevant human stem cells [Mob DNA. 2019] PubMed

Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome [Mob DNA. 2019] PubMed

Origins and evolution of CRISPR-Cas systems [Philos Trans R Soc Lond B Biol Sci. 2019] PubMed

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells [Nat Commun. 2019] PubMed

Gorillas have been infected with the HERV-K (HML-2) endogenous retrovirus much more recently than humans and chimpanzees [Proc Natl Acad Sci U S A. 2019] PubMed

Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids [Retrovirology. 2019] PubMed

RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena [Genes Dev. 2019] PubMed

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice [Nat Commun. 2019] PubMed

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools [Cold Spring Harb Perspect Biol. 2019] PubMed

Alu element insertion in the MLH1 exon 6 coding sequence as a mutation predisposing to Lynch syndrome [Hum Mutat 2019] PubMed

L1 drives IFN in senescent cells and promotes age-associated inflammation [Nature 2019] PubMed

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling [Nature 2019] PubMed

CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species. [BMC Genomics 2019] PubMed

Evolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty. [Sci Rep 2019] PubMed

CDI/CDS system-encoding genes of Burkholderia thailandensis are located in a mobile genetic element that defines a new class of transposon. [PLoS Genet. 2019]

Horizontal transfer of a retrotransposon from the rice planthopper to the genome of an insect DNA virus. [J Virol. 2019]

PePIF1, a P-lineage of PIF-like transposable element identified in protocorm-like bodies of Phalaenopsis orchids. [BMC Genomics. 2019]

Systematic survey of plant LTR-retrotransposons elucidates phylogenetic relationships of their polyprotein domains and provides a reference for element classification. [Mob DNA. 2019]

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes. [Genome Res. 2019] PubMed

Gene duplication and genetic innovation in cereal genomes. [Genome Res. 2019] PubMed

High-Throughput Targeted Repeat Element Bisulfite Sequencing (HT-TREBS). [Methods Mol Biol. 2019] PubMed

Heterogeneity of transposon expression and activation of the repressive network in human fetal germ cells. [Development. 2019] PubMed

Retrophylogenomics in rorquals indicate large ancestral population sizes and a rapid radiation. [Mob DNA. 2019] PubMed

Dynamic methylation of an L1 transduction family during reprogramming and neurodifferentiation. [Mol Cell Biol. 2019] PubMed

A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System. [Mol Cell. 2019] PubMed

Genomic Takeover by Transposable Elements in the Strawberry Poison Frog. [Mol Biol Evol. 2018] PubMed

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks [Nature. 2018] PubMed

High-performance gene expression and knockout tools using sleeping beauty transposon system. [Mob DNA. 2018] PubMed

MITE Tracker: an accurate approach to identify miniature inverted-repeat transposable elements in large genomes. [BMC Bioinformatics. 2018] PubMed

Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. [Nucleic Acids Res. 2018] PubMed

PiggyBac Transposon-Based Insertional Mutagenesis in Mice. [Methods Mol Biol. 2019] PubMed

Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery. [Methods Mol Biol. 2019] PubMed

Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis. [Methods Mol Biol. 2019] PubMed

Transposable element insertions in fission yeast drive adaptation to environmental stress. [Genome Res. 2018] PubMed

Variation in proviral content among human genomes mediated by LTR recombination. [Mob DNA. 2018] PubMed

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis. [Mob DNA. 2018] PubMed

A Robust Transposon-Endogenizing Response from Germline Stem Cells. [Dev Cell. 2018] PubMed

Drosophila small ovary gene is required for transposon silencing and heterochromatin organisation and ensures germline stem cell maintenance and differentiation. [Development. 2018] PubMed

Transposase mapping identifies the genomic targets of BAP1 in uveal melanoma. [BMC Med Genomics. 2018] PubMed

Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. [Proc Natl Acad Sci USA. 2018] PubMed

True Homoplasy of Retrotransposon Insertions in Primates. [Syst Biol. 2018] PubMed

An advanced enrichment method for rare somatic retroelement insertions sequencing. [Mob DNA. 2018] PubMed

TETyper: a bioinformatic pipeline for classifying variation and genetic contexts of transposable elements from short-read whole-genome sequencing data. [Microb Genom. 2018] PubMed

ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses. [Proc Natl Acad Sci USA. 2018] PubMed

Testing the retroelement invasion hypothesis for the emergence of the ancestral eukaryotic cell. [Proc Natl Acad Sci USA. 2018] PubMed

Ten things you should know about transposable elements. [Genome Biol. 2018] PubMed

Bacterial group II introns generate genetic diversity by circularization and trans-splicing from a population of intron-invaded mRNAs. [PLoS Genet. 2018] PubMed

Mobilization of Pack-CACTA transposons in Arabidopsis suggests the mechanism of gene shuffling. [Nucleic Acids Res. 2018] PubMed

Genome-Wide Mapping of Yeast Retrotransposon Integration Target Sites. [Methods Enzymol. 2018] PubMed

NP220 mediates silencing of unintegrated retroviral DNA. [Nature. 2018] PubMed

An Analysis of IS630/Tc1/mariner Transposons in the Genome of a Pacific Oyster, Crassostrea gigas. [J Mol Evol. 2018] PubMed

Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. [Elife. 2018] PubMed

Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. [Nucleic Acids Res. 2018] PubMed 

Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis. [Proc Natl Acad Sci USA. 2018] PubMed

Transposase subunit architecture and its relationship to genome size and the rate of transposition in prokaryotes and eukaryotes. [Nucleic Acids Res. 2018] PubMed

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. [Cell. 2018] PubMed

Serine Integrase attP Binding and Specificity. [J Mol Biol. 2018] PubMed

Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length. [PLoS Biol. 2018] PubMed

Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. [Nucleic Acids Res. 2018] PubMed

Hypomethylation, endogenous retrovirus expression, and interferon signaling in testicular germ cell tumors. [Proc Natl Acad Sci U S A. 2018] PubMed

Transposons take remote control. [Elife. 2018] PubMed

The PMEL Gene and Merle in the Domestic Dog: A Continuum of Insertion Lengths Leads to a Spectrum of Coat Color Variations in Australian Shepherds and Related Breeds. [Cytogenet Genome Res. 2018] PubMed

Mobile Genetic Elements Associated with Antimicrobial Resistance. [Clin Microbiol Rev. 2018] PubMed

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins. [Mol Neurodegener. 2018] PubMed

HIV-1 Vpr and p21 restrict LINE-1 mobility. [Nucleic Acids Res. 2018] PubMed

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion. [Proc Natl Acad Sci USA. 2018] PubMed

Assessing genome assembly quality using the LTR Assembly Index (LAI). [Nucleic Acids Res. 2018] PubMed

Stress affects the epigenetic marks added by natural transposable element insertions in Drosophila melanogaster. [Sci Rep. 2018] PubMed

Length variations within the Merle retrotransposon of canine PMEL: correlating genotype with phenotype. [Mob DNA. 2018] PubMed

Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells. [Stem Cells Int. 2018] PubMed

Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. [Cell. 2018] PubMed

Impact of transposable elements on genome structure and evolution in wheat. [Genome Biol. 2018] PubMed

LINE-ing Up to Influence Splicing [Cell. 2018] Video abstract

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing [Cell. 2018] PubMed

Hijacking Oogenesis Enables Massive Propagation of LINE and Retroviral Transposons [Cell. 2018] PubMed

Impact of non-LTR retrotransposons in the differentiation and evolution of anatomically modern humans. [Mob DNA. 2018] PubMed

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins [Mol Neurodegener. 2018] PubMed

Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers. [Genome Res. 2018] PubMed

Genome-Wide Determination of Gene Essentiality by Transposon Insertion Sequencing in Yeast Pichia pastoris. [Sci Rep. 2018] PubMed

LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs. [BMC Genomics. 2018] PubMed

Contrasting Rates of LINE-1 Amplification among New World Primates of the Atelidae Family. [Cytogenet Genome Res. 2018] PubMed

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. [Cell. 2018] PubMed

Drosophila parasitoid wasps bears a distinct DNA transposon profile. [Mob DNA. 2018] PubMed

L1 retrotransposition in the soma: a field jumping ahead. [Mob DNA. 2018] PubMed

A high throughput screen for active human transposable elements. [BMC Genomics. 2018] PubMed

Retrotransposon-induced mosaicism in the neural genome. [Open Biol. 2018] PubMed

TIP60 represses activation of endogenous retroviral elements. [Nucleic Acids Res. 2018] PubMed

Nimble and Ready to Mingle: Transposon Outbursts of Early Development. [Trends Genet. 2018] PubMed

Hijacking Oogenesis Enables Massive Propagation of LINE and Retroviral Transposons. [Cell. 2018] PubMed

The maize W22 genome provides a foundation for functional genomics and transposon biology. [Nat Genet. 2018] PubMed

Transcriptional control and exploitation of an immune-responsive family of plant retrotransposons. [EMBO J. 2018] PubMed

YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. [Proc Natl Acad Sci USA. 2018] PubMed

Insect retroelements provide novel insights into the origin of hepatitis B viruses. [Mol Biol Evol. 2018] PubMed

Border collies of the genome: domestication of an autonomous retrovirus-like transposon. [Curr Genet. 2018] PubMed

Tie-Break: Host and Retrotransposons Play tRNA. [Trends Cell Biol. 2018] PubMed

A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. [Cell. 2018] PubMed

Convergent evolution of integration site selection upstream of tRNA genes by yeast and amoeba retrotransposons. [Nucleic Acids Res. 2018] PubMed

Transposable elements and gene expression during the evolution of amniotes. [Mob DNA. 2018] PubMed

Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression. [EMBO J. 2018] PubMed

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages. [PLoS Genet. 2018] PubMed

L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution. [Cell Rep. 2018] PubMed

Non-viral therapeutic cell engineering with the Sleeping Beauty transposon system. [Curr Opin Genet Dev. 2018] PubMed

RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition. [EMBO J. 2018] PubMed

Retrotransposon targeting to RNA polymerase III-transcribed genes. [Mob DNA. 2018] PubMed

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis. [Science. 2018] PubMed

Mobilization of retrotransposons as a cause of chromosomal diversification and rapid speciation: the case for the Antarctic teleost genus Trematomus. [BMC Genomics. 2018] PubMed

The case for not masking away repetitive DNA. [Mob DNA. 2018] PubMed

Oocyte Quality Control: Causes, Mechanisms, and Consequences. [Cold Spring Harb Symp Quant Biol. 2018] PubMed

Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross-Talk and a Second Function for Ure2p in Saccharomyces cerevisiae. [Genetics. 2018] PubMed

Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression. [Proc Natl Acad Sci U S A. 2018] PubMed

Contrasted patterns of evolution of the LINE-1 retrotransposon in perissodactyls: the history of a LINE-1 extinction. [Mob DNA. 2018] PubMed

The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. [Mob DNA. 2018] PubMed

Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering. [Nucleic Acids Res. 2018] PubMed

A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. [Mob DNA. 2018] PubMed

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis. [Genome Res. 2018] PubMed

Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes. [Genome Res. 2018] PubMed

Horizontal transfer of retrotransposons between bivalves and other aquatic species of multiple phyla. [Proc Natl Acad Sci USA. 2018] PubMed

A machine learning based framework to identify and classify long terminal repeat retrotransposons. [PLos Comput Biol. 2018] PubMed

Control of yeast retrotransposons mediated through nucleoporin evolution. [PLos Genet. 2018] PubMed

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. [Science. 2018] PubMed

Spliced integrated retrotransposed element (SpIRE) formation in the human genome. [PLoS Biol. 2018] PubMed

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities. [PLoS Pathog. 2018]PubMed 

Reading the tea leaves: Dead transposon copies reveal novel host and transposon biology. [PLoS Biol. 2018] PubMed 

The yeast Ty1 retrotransposon requires components of the nuclear pore complex for transcription and genomic integration. [Nucleic Acids Res. 2018] PubMed

Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance. [Cell. 2018] PubMed  

Preferential Ty1 retromobility in mother cells and nonquiescent stationary phase cells is associated with increased concentrations of total Gag or processed Gag and is inhibited by exposure to a high concentration of calcium. [Aging. 2018] PubMed

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p. [Elife. 2018] PubMed 

Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes. [Genome Res. 2018] PubMed

Early life experience drives structural variation of neural genomes in mice. [Science. 2018] PubMed 

Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology. [Curr Opin Genet Dev. 2018] PubMed 

Double insertion of transposable elements provides a substrate for the evolution of satellite DNAs. [Genome Res. 2018] PubMed

Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays. [Mol Cell. 2018] PubMed  

Helraiser intermediates provide insight into the mechanism of eukaryotic replicative transposition. [Nat Commun. 2018] PubMed 

Mammalian transposable elements and their impacts on genome evolution. [Chromosome Res. 2018] PubMed

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation. [Cell. 2018] PubMed

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. [Cell. 2018] PubMed

Sleeping Beauty transposon integrates into non-TA dinucleotides. [Mob DNA. 2018] PubMed

The Birth and Demise of the ISApl1-mcr-1-ISApl1 Composite Transposon: the Vehicle for Transferable Colistin Resistance. [MBio. 2018] PubMed

Comparative genome analysis of 52 fish species suggests differential associations of repetitive elements with their living aquatic environments. [BMC Genomics. 2018] PubMed

The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters. [PLoS Genet. 2018] PubMed

LINE-1 protein localization and functional dynamics during the cell cycle. [Elife. 2018] PubMed

Dissection of affinity captured LINE-1 macromolecular complexes. [Elife. 2018] PubMed

Human transposable elements in Repbase: genomic footprints from fish to humans. [Mob DNA. 2018] PubMed

Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells. [Mob DNA. 2018] PubMed

Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition. [Nucleic Acids Res. 2018] PubMed

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. [Cell. 2018] PubMed

Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons. [Cell. 2018] PubMed

Transposon-derived small RNAs triggered by miR845 mediate genome dosage response in Arabidopsis. [Nat Genet. 2018] PubMed

SETDB1 prevents TET2-dependent activation of IAP retroelements in naïve embryonic stem cells. [Genome Biol. 2018] PubMed

The axolotl genome and the evolution of key tissue formation regulators. [Nature. 2018] PubMed

The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms. [Nature. 2018] PubMed

A novel family of tyrosine integrases encoded by the temperate pleolipovirus SNJ2. [Nucleic Acids Res. 2018] PubMed

Targeted deletion of a 170 kb cluster of LINE1 repeats: implications for regional control. [Genome Res. 2018] PubMed

Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells. [Nature 2018]

Characterization of a functional insertion sequence ISSau2 from Staphylococcus aureus. [Mob DNA. 2018 Jan] PubMed

Rewired RNAi-mediated genome surveillance in house dust mites. [PLoS Genet. 2018] PubMed

Maize Transposable Elements Ac/Ds as Insertion Mutagenesis Tools in Candida albicans.
[G3 (Bethesda). 2018] PubMed

Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase. [Nucleic Acids Res. 2018] PubMed

Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain. [Mob DNA. 2017] PubMed

piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. [Nature. 2017] PubMed

Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.[Nature. 2017] PubMed

piRNA-mediated regulation of transposon alternative splicing in the soma and germ line. [Nature. 2017] PubMed

Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications [Mol Cell. 2017] PubMed

Host factors that promote retrotransposon integration are similar in distantly related eukaryotes. [PLoS Genet. 2017] PubMed

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1. [Proc Natl Acad Sci USA. 2017] PubMed

Transcription coupled repair and biased insertion of human retrotransposon L1 in transcribed genes. [Mob DNA. 2017] PubMed

LINE-1 Retrotransposons in Healthy and Diseased Human Brain. [Dev Neurobiol. 2017] PubMed

Editorial: Mobile Genetic Elements in Cellular Differentiation, Genome Stability, and Cancer. [Front Chem. 2017] PubMed

De-novo emergence of SINE retroposons during the early evolution of passerine birds. [Mob DNA. 2017] PubMed

Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites. [Mob DNA. 2017] PubMed

Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferences. [Mol Microbiol. 2017] PubMed

PIWI-Interacting RNA in Drosophila: Biogenesis, Transposon Regulation, and Beyond. [Chem Rev. 2017] PubMed

ZmCCT9 enhances maize adaptation to higher latitudes. [Proc Natl Acad Sci USA 2017] PubMed

Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering. [Nucleic Acids Res. 2017] PubMed

New reference genome sequences of hot pepper reveal the massive evolution of plant disease-resistance genes by retroduplication. [Genome Biol. 2017] PubMed

TGTT and AACA: two transcriptionally active LTR retrotransposon subfamilies with a specific LTR structure and horizontal transfer in four Rosaceae species. [Mob DNA. 2017] PubMed

High-frequency recombination between members of an LTR retrotransposon family during transposition bursts. [Nat Commun. 2017] PubMed

DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA. [Proc Natl Acad Sci U S A. 2017] PubMed

tRNA-derived small RNAs: New players in genome protection against retrotransposons. [RNA Biol. 2017 ] PubMed

Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. [Mol Cell. 2017] PubMed

Globular domain structure and function of restriction-like-endonuclease LINEs: similarities to eukaryotic splicing factor Prp8. [Mob DNA. 2017] PubMed

Genome sequence of the progenitor of the wheat D genome Aegilops tauschii. [Nature. 2017]

Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey. [Nucleic Acids Res. 2017] PubMed

Mobile genetic elements and evolution of CRISPR-Cas systems: all the way there and back. [Genome Biol Evol. 2017] PubMed

Retrotransposons: Stowaways in the Primordial Germline. [Curr Biol. 2017] PubMed

Genetic Drift, Not Life History or RNAi, Determine Long-Term Evolution of Transposable Elements. [Genome Biol Evol. 2017] PubMed

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. [PLoS Genet. 2017] PubMed

Viral communities of the human gut: metagenomic analysis of composition and dynamics. [Mob DNA. 2017] PubMed

Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells. [Nucleic Acids Res. 2017] PubMed

A single active site in the mariner transposase cleaves DNA strands of opposite polarity. [Nucleic Acids Res. 2017] PubMed

Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae. [Genetics. 2017] PubMed

Improved maize reference genome with single-molecule technologies. [Nature. 2017] PubMed

Retrotransposon Domestication and Control in Dictyostelium discoideum. [Front Microbiol. 2017] PubMed

SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers. [Nucleic Acids Res. 2017] PubMed

A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement. [Nucleic Acids Res. 2017] PubMed

Horizontal transfer of non-LTR retrotransposons from arthropods to flowering plants. [Mol Biol Evol. 2017] PubMed

CLIFinder: Identification of LINE-1 Chimeric Transcripts in RNA-seq data. [Bioinformatics. 2017] PubMed

Transposons As Tools for Functional Genomics in Vertebrate Models. [Trends Genet. 2017] PubMed

How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration. [Nature. 2017] PubMed

The TREX1 Dinosaur Bites the Brain through the LINE. [Cell Stem Cell. 2017] PubMed

Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer. [Philos Trans R Soc Lond B Biol Sci. 2017] PubMed

Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. [Curr Biol. 2017] PubMed

Gene Therapy with the Sleeping Beauty Transposon System. [Trends Genet. 2017] PubMed

Alu Insertion Polymorphisms as Evidence for Population Structure in Baboons. [Genome Biol Evol. 2017] PubMed

A fine LINE-1 in mouse embryonic chromatin regulation. [Nat Genet. 2017] PubMed

Integrative and conjugative elements and their hosts: composition, distribution and organization. [Nucleic Acids Res. 2017] PubMed

Complete fusion of a transposon and herpesvirus created the Teratorn mobile element in medaka fish. [Nat Commun. 2017] PubMed

Similar Evolutionary Trajectories for Retrotransposon Accumulation in Mammals. [Genome Biol Evol. 2017] PubMed

A fine LINE-1 in mouse embryonic chromatin regulation. [Nat Genet. 2017] PubMed

Barbara McClintock's Final Years as Nobelist and Mentor: A Memoir. [Cell. 2017] PubMed

Mobile DNA in Health and Disease. [N Engl J Med. 2017 July] PubMed

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses. [PLoS Genet. 2017 July] PubMed

Comprehensive arrayed transposon mutant library of Klebsiella pneumoniae outbreak strain KPNIH1. [J Bacteriol. 2017 July] PubMed

Discovery of rare, diagnostic AluYb8/9 elements in diverse human populations. [Mob DNA. 2017 July] PubMed

Recruitment of CRISPR-Cas systems by Tn7-like transposons. [Proc Natl Acad Sci USA. 2017 Aug] PubMed

Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. [Elife. 2017 Aug] PubMed

Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. [Cell Stem Cell. 2017 Aug] PubMed

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism. [Nat Struct Mol Biol. 2017 June] PubMed

L1 Mosaicism in Mammals: Extent, Effects, and Evolution. [Trends Genet. 2017 Aug] PubMed

Environmentally triggered genomic plasticity and capsular polysaccharide formation are involved in increased ethanol and acetic acid tolerance in Kozakia baliensis NBRC 16680. [BMC Microbiol. 2017 Aug] PubMed

A genome-wide transcriptome and translatome analysis of Arabidopsis transposons identifies a unique and conserved genome expression strategy for Ty1/Copia retroelements. [Genome Res. 2017 Aug] PubMed

HISTONE DEACETYLASE6 Acts in Concert with Histone Methyltransferases SUVH4, SUVH5, and SUVH6 to Regulate Transposon Silencing. [Plant Cell. 2017 Aug] PubMed

Developmental Restriction of Retrotransposition Activated in Arabidopsis by Environmental Stress. [Genetics. 2017 Aug] PubMed

Human Retrotransposon Insertion Polymorphisms Are Associated with Health and Disease via Gene Regulatory Phenotypes. [Front Microbiol. 2017 Aug] PubMed

Transposon Sequencing Uncovers an Essential Regulatory Function of Phosphoribulokinase for Methylotrophy. [Curr Biol. 2017 Aug] PubMed

Mobile Group II Introns as Ancestral Eukaryotic Elements. [Trends Genet. 2017 Aug] PubMed

Landscape and variation of novel retroduplications in 26 human populations. [PLoS Comput Biol. 2017 June] PubMed

MGEScan: a Galaxy-based system for identifying retrotransposons in genomes. [Bioinformatics 2016 Aug] PubMed

Transposon Insertion Site Sequencing for Synthetic Lethal Screening. [Methods Mol Biol. 2017 Aug] PubMed

LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. [Nat. Genet. 2017 Aug] PubMed

rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. [PLoS Genet. 2017 Aug] PubMed

TnseqDiff: identification of conditionally essential genes in transposon sequencing studies. [BMC Bioinformatics. 2017 July] PubMed

Fusion of a superfamily 1 helicase and an inactivated DNA polymerase is a signature of common evolutionary history of Polintons, polinton-like viruses, Tlr1 transposons and transpovirons. [Virus Evol. 2016 June] PubMed

Structures of the CRISPR genome integration complex. [Science. 2017 July] PubMed

Resolving the prevalence of somatic transposition in Drosophila. [Elife. 2017 July] PubMed

Drosophila: Retrotransposons Making up Telomeres. [Viruses. 2017 July] PubMed

Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses. [Genetics. 2017 July] PubMed

Canalization by Selection of De Novo-Induced Mutations. [Genetics. 2017 June] PubMed

Giant reverse transcriptase-encoding transposable elements at telomeres. [Mol Biol Evol. 2017 May] PubMed

The Role of Somatic L1 Retrotransposition in Human Cancers. [Viruses. 2017 May] PubMed

Analysis of LINE-1 Elements in DNA from Postmortem Brains of Individuals with Schizophrenia. [Neuropsychopharmacology. 2017 June] PubMed

Making serine integrases work for us. [Curr Opin Microbiol. 2017 June] PubMed

Retrotransposons are specified as DNA replication origins in the gene-poor regions of Arabidopsis heterochromatin. [Nucleic Acids Res. 2017 June] PubMed

Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements. [PLoS Pathog. 2017 June] PubMed

Intact piRNA pathway prevents L1 mobilization in male meiosis. [Proc Natl Acad Sci USA. 2017 June] PubMed

Transposable elements in cancer. [Epub 2017 June] PubMed

DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation. [Proc Natl Acad Sci USA. 2017 June] PubMed

Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells. [Nucleic Acids Res. 2017 June] PubMed

LTR-Retrotransposon Control by tRNA-Derived Small RNAs. [J Cell Sci. 2017 June] PubMed

Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain. [BMC Biol. 2017 June] PubMed

Retroviral intasomes arising. [Curr Opin Struct Biol. 2017 Apr] PubMed

Piwi Is Required during Drosophila Embryogenesis to License Dual-Strand piRNA Clusters for Transposon Repression in Adult Ovaries. [Mol Cell. 2017 Apr] PubMed

Evolutionary history of LTR-retrotransposons among 20 Drosophila species. [Mob DNA. 2017 Apr] PubMed

Structural variants caused by Alu insertions are associated with risks for many human diseases. [Proc Natl Acad Sci U S A. 2017 May] PubMed

Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery. [Curr Opin Microbiol. 2017 May] PubMed

Heritable L1 retrotransposition in the mouse primordial germline and early embryo. [Genome Res. 2017 May] PubMed

Transposition of Mutator-like transposable elements (MULEs) resembles hAT and Transib elements and V(D)J recombination. [Nucleic Acids Res. 2017 May] PubMed

Functional mapping of yeast genomes by saturated transposition. [Elife. 2017 May] PubMed

Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration. [Mob DNA. 2017 May] PubMed

MAGenTA; a Galaxy implemented tool for complete Tn-Seq analysis and data visualization. [Bioinformatics. 2017 May] PubMed

Integration site selection by retroviruses and transposable elements in eukaryotes. [Nat Rev Genet. 2017 May] PubMed

A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568. [Science. 2017 May] PubMed

Coiled-coil interactions mediate serine integrase directionality. [Nucleic Acids Res. 2017 May] PubMed

Characterization of autonomous families of Tc1/mariner transposons in neoteleost genomes. [Mar Genomics. 2017 May] PubMed

Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea. [Nat Microbiol. 2017 Apr] PubMed

Structure of Ty1 Internally Initiated RNA Influences Restriction Factor Expression. [Viruses. 2017 Apr] PubMed

Integration site selection by retroviruses and transposable elements in eukaryotes. [Nature. 2017 March] PubMed

LoRTE: Detecting transposon-induced genomic variants using low coverage PacBio long read sequences. [Mob DNA. 2017 Apr] PubMed

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI). [Science. 2017 Apr] PubMed

LTRtype, an Efficient Tool to Characterize Structurally Complex LTR Retrotransposons and Nested Insertions on Genomes. [Front Plant Sci. 2017 Apr] PubMed

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. [Nucleic Acids Res. 2017 Apr] PubMed

Aubergine Controls Germline Stem Cell Self-Renewal and Progeny Differentiation via Distinct Mechanisms. [Dev Cell. 2017 Apr] PubMed

Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA. [Viruses. 2017 Apr] PubMed

Natural variation of piRNA expression affects immunity to transposable elements. [PLoS Genet. 2017 Apr] PubMed

Insertion and deletion polymorphisms of the ancient AluS family in the human genome. [Mob DNA. 2017 Apr] PubMed

LINE Insertion Polymorphisms are Abundant but at Low Frequencies across Populations of Anolis carolinensis. [Front Genet. 2017 Apr] PubMed

Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export. [Nucleic Acids Res. 2017 Mar] PubMed

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion. [Nucleic Acids Res. 2017 Mar] PubMed

Inhibition of human endogenous retrovirus-K by antiretroviral drugs. [Retrovirology. 2017 Mar] PubMed

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. [Nature. 2017 Mar] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Proc Natl Acad Sci U S A. 2017 Mar] PubMed 

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. [J Cell Sci. 2017 Mar] PubMed 

Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3. [Viruses. 2017 Mar] PubMed

Convergence of retrotransposons in oomycetes and plants. [Mob DNA. 2017 Mar] PubMed

Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. [Genetics. 2017 Mar] PubMed

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. [PLoS Genet. 2017 Mar] PubMed

Speciation network in Laurasiatheria: retrophylogenomic signals. [Genome Res. 2017 Mar] PubMed

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. [Nat Genet. 2017 Mar] PubMed

A transposon-derived small RNA regulates gene expression in Salmonella Typhimurium. [Nucleic Acids Res. 2017 Feb] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Nucleic Acids Res. 2017 Feb] PubMed

A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. [Sci Rep. 2017 Feb] PubMed

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal. [E Life. 2017 Feb] PubMed

The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. [Clin Chem. 2017 Feb] PubMed

Transposition of the bamboo Mariner-like element Ppmar1 in yeast. [Mol Phylogenet Evol. 2017 Feb] PubMed

Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis. [J Biol Chem. 2017 Feb] PubMed

Sequencing the extrachromosomal circular mobilome reveals retrotransposon activity in plants. [PLoS Genet. 2017 Feb 17] PubMed

ALUternative Regulation for Gene Expression. [Trends Cell Biol. 2017 Feb] PubMed

Transposable Element Bm1645 is a Source of BmAGO2-associated Small RNAs that affect its expression in Bombyx mori. [BMC Genomics. 2017 Feb] PubMed

Conserved expression of transposon-derived non-coding transcripts in primate stem cells. [BMC Genomics. 2017 Feb] PubMed

Single genome retrieval of context-dependent variability in mutation rates for human germline. [BMC Genomics. 2017 Jan] PubMed

Hsp90 and physiological stress are linked to autonomous transposon mobility and heritable genetic change in nematodes. [Genome Biol Evol. 2017 Jan] PubMed

An optimized, broadly applicable piggyBac transposon induction system. [Nucleic Acids Res. 2017 Jan] PubMed

Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition. [Genetics. 2017 Jan] PubMed

The FACT complex promotes avian leukosis virus DNA integration. [J Virol. 2017 Jan] PubMed

G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. [Nat Struct Mol Biol. 2017 Jan] PubMed

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. [Nucleic Acids Res. 2017 Jan] PubMed

Transposase-Mediated Excision, Conjugative Transfer and Diversity of ICE6013 in Staphylococcus aureus. [J Bacteriol. 2017 Jan] PubMed

Protein splicing of a recombinase intein induced by ssDNA and DNA damage. [Genes Dev. 2016 Dec] PubMed

Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. [Genes Dev. 2016 Dec] PubMed

A supramolecular assembly mediates lentiviral DNA integration. [Science. 2017 Jan] PubMed

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. [Science. 2017 Jan] PubMed

Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis. [Appl Environ Microbiol. 2017 Jan] PubMed

piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

GB3.0: a platform for plant bio-design that connects functional DNA elements with associated biological data. [Nucleic Acids Res. 2017 Jan] PubMed 

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition. [Genetics. 2017 Jan] PubMed

TET enzymes: double agents in the transposable element-host genome conflict. [Genome Biol. 2016 Dec] PubMed

Endogenous retroviral promoter exaptation in human cancer. [Mob DNA. 2016 Dec] PubMed

Incidental mutations occur frequently during transposon mutagenesis. [FEMS Microbiol Lett. 2016 Dec] PubMed

Paralog-Specific Functions of RPL7A and RPL7B Mediated by Ribosomal Protein or snoRNA Dosage in Saccharomyces cerevisiae. [G3 (Bethesda). 2016 Dec] PubMed

DNA binding specificities of Escherichia coli Cas1-Cas2 integrase drive its recruitment at the CRISPR locus. [Nucleic Acids Res. 2016 Dec] PubMed

Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion. [Nucleic Acids Res. 2016 Dec] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Multiple Transcriptional and Post-Transcriptional Pathways Collaborate To Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast. [Genetics. 2016 Dec] PubMed

Non-canonical Helitrons in Fusarium oxysporum. [Mob DNA. 2016 Dec] PubMed

Destabilization of B2 RNA by EZH2 Activates the Stress Response. [Cell. 2016 Dec] PubMed

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells. [Genome Res. 2017 Jan] PubMed

Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition. [Nucleic Acids Res. 2017 Jan] PubMed

L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes. [Nucleic Acids Res. 2017 Jan] PubMed

Telomeric Retrotransposon HeT-A Contains a Bidirectional Promoter that Initiates Divergent Transcription of piRNA Precursors in Drosophila Germline. [J Mol Biol. 2016 Dec] PubMed

Engineered LINE-1 retrotransposition in non-dividing human neurons. [Genome Res. 2016 Dec] PubMed

New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination. [FEBS J. 2016 Dec] PubMed

A map of mobile DNA insertions in the NCI-60 human cancer cell panel. [Mob DNA. 2016 Oct] PubMed

MTV, an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in Drosophila. [PLoS Genet. Nov 2016] PubMed

Retroviruses integrate into a shared, non-palindromic DNA motif. Nat Microbiol. 2016 Nov] PubMed 

Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme. [Mob DNA. 2016 Nov] PubMed

Somatic retrotransposition is infrequent in glioblastomas. [Mob DNA. 2016 Nov] PubMed

Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression. [Proc Natl Acad Sci U S A. 2016 Nov] PubMed

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity. [Science. 2016 Nov] PubMed

Numerous small hammerhead ribozyme variants associated with Penelope-like retrotransposons cleave RNA as dimers. [RNA Biol. 2016 Nov] PubMe

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Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder. [Sci Rep. 2016 Nov] PubMed

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences. [Mol Cell. 2016 Dec] PubMed

Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition. [Mob DNA. 2016 Nov] PubMed

Patterns of Transposable Element Expression and Insertion in Cancer. [Front Mol Biosci. 2016 Nov] PubMed

Temporal self-regulation of transposition through host-independent transposase rodlet formation. [Nucleic Acids Res. 2017 Jan] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Close ecological relationship among species facilitated horizontal transfer of retrotransposons. [BMC Evol Biol. Oct 2016] PubMed

In vivo continuous evolution of genes and pathways in yeast. [Nat Commun. Oct 2016] PubMed

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LINEs between species: Evolutionary dynamics of LINE-1 retrotransposons across the eukaryotic tree of life. [Genome Biol Evol. Oct 2016] PubMed

Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis. [Methods Mol Biol. 2017] PubMed

Assembly and transfer of tripartite integrative and conjugative genetic elements. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Retrotransposon-mediated aluminum tolerance through enhanced expression of the citrate transporter OsFRDL4. [Plant Physiol. Oct 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

Profiling Transposable Elements and Their Epigenetic Effects in Non-model Species. [Methods Mol Biol. 2017] PubMed

Genomics and the evolution of antibiotic resistance. [Ann N Y Acad Sci. Oct 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

p53 in the game of transposons. [Bioessays. Nov 2016] PubMed

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Drug resistant integrase mutants cause aberrant HIV integrations. [Retrovirology. Sep 2016] PubMed

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Convergent evolution of tRNA gene targeting preferences in compact genomes. [Mob DNA. Aug 2016] PubMed

Protecting genome integrity during CRISPR immune adaptation. [Nat Struct Mol Biol. Oct 2016] PubMed

Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity. [PLoS One. Sep 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

The flow of the gibbon LAVA element is facilitated by the LINE-1 retrotransposition machinery. [Genome Biol Evol. Sep 2016] PubMed

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Helitron-like transposons contributed to the mating system transition from out-crossing to self-fertilizing in polyploid Brassica napus L. [Sci Rep. Sep 2016] PubMed

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ADAR1 restricts LINE-1 retrotransposition. [Nucleic Acids Res. Sep 2016] PubMed

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Restricting retrotransposons: a review. [Mob DNA. Aug 2016] PubMed

Piwi Modulates Chromatin Accessibility by Regulating Multiple Factors Including Histone H1 to Repress Transposons. [Mol Cell. Aug 2016] PubMed

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis. [Cell. Aug 2016] PubMed

Direct interrogation of the role of H3K9 in metazoan heterochromatin function. [Genes Dev. Aug 2016] PubMed

Production of Small Non-coding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster. [Genetics. Aug 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites. [Nucleic Acids Res. Aug 2016] PubMed

The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes. [Genome Biol Evol. Sep 2016] PubMed

Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome. [Mob DNA. Jul 2016] PubMed

Genome-wide characterization of non-reference transposons in crops suggests non-random insertion. [BMC Genomics. Aug 2016] PubMed

Identification of polymorphic SVA retrotransposons using a mobile element scanning method for SVA (ME-Scan-SVA). [Mob DNA. Jul 2016] PubMed

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. [Nat Biotechnol. Sep 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. June 2016] PubMed

Experimental single-strain mobilomics reveals events that shape pathogen emergence. [Nucleic Acids Res. July 2016] PubMed

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CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. [EMBO Rep. July 2016] PubMed

Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3. [Viruses. July 2016] PubMed

APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity. [PLoS One. July 2016] PubMed

Virus-like attachment sites as structural landmarks of plants retrotransposons. [Mob DNA. July 2016] PubMed

A pair of transposon-derived proteins regulate active DNA demethylation in Arabidopsis. [EMBO J. July 2016] PubMed

Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma. [Proc Natl Acad Sci USA. May 2016] PubMed

Methods for accurate quantification of LTR-retrotransposon copy number using short-read sequence data: a case study in Sorghum. [Mol Genet Genomics. June 2016] PubMed

Transposable Elements versus the Fungal Genome: Impact on Whole-Genome Architecture and Transcriptional Profiles. [PLoS Genet. June 2016] PubMed

Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination. [Cell. June 2016] PubMed

PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice. [Sci Rep. June 2016] PubMed

Repetitive element hypermethylation in multiple sclerosis patients. [BMC Genet. June 2016] PubMed

CRISPR Outsourcing: Commissioning IHF for Site-Specific Integration of Foreign DNA at the CRISPR Array. [Mol Cell. June 2016] PubMed

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma. [Hum Mutat. June 2016] PubMed

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen. [Genome Res. June 2016] PubMed

Retrozymes are a unique family of non-autonomous retrotransposons with hammerhead ribozymes that propagate in plants through circular RNAs. [Genome Biol. June 2016] PubMed

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization. [Genetics. June 2016] PubMed

Analysis of tandem gene copies in maize chromosomal regions reconstructed from long sequence reads. [Proc Natl Acad Sci USA. June 2016] PubMed

Evidence of G.O.D.'s Miracle: Unearthing a RAG Transposon. [Cell. June 2016] PubMed

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Genomic analysis of mouse VL30 retrotransposons. [Mob DNA. May 2016] PubMed

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A bend, flip and trap mechanism for transposon integration. [eLife. May 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. Jun 2016] PubMed

Quantitative Insertion-site Sequencing (QIseq) for high throughput phenotyping of transposon mutants. [Genome Res. May 2016] PubMed

Next-generation sequencing-based detection of germline L1-mediated transductions. [BMC Genomics. May 2016] PubMed

DjPiwiB: A Rich Nuclear Inheritance for Descendants of Planarian Stem Cells. [Dev Cell. May 2016] PubMed

Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian. [Dev Cell. May 2016] PubMed

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Exploration of the Drosophila buzzatii transposable element content suggests underestimation of repeats in Drosophila genomes. [BMC Genomics. May 2016] PubMed

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen. [BMC Med Genomics. Apr 2016] PubMed

Alternative Computational Analysis Shows No Evidence for Nucleosome Enrichment at Repetitive Sequences in Mammalian Spermatozoa. [Dev Cell. Apr 2016] PubMed

Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. [Aging Cell. Apr 2016] PubMed

Alu SINE analyses of 3,000-year-old human skeletal remains: a pilot study. [Mob DNA. Apr 2016] PubMed

The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations. [Mob DNA. Apr 2016] PubMed

LINE-1-like retrotransposons contribute to RNA-based gene duplication in dicots. [Sci Rep. Apr 2016] PubMed

Brujita Integrase: A simple, arm-less, directionless, and promiscuous tyrosine integrase system. [J Mol Biol. Apr 2016] PubMed

Identification and analysis of integrons and cassette arrays in bacterial genomes. [Nucleic Acids Res. Apr 2016] PubMed

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes. [Nat Commun. Mar 2016] PubMed

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Both exact target site sequence and long poly(A) tail are required for precise insertion of the 18S rDNA-specific non-long terminal repeat retrotransposon R7Ag. [Mol Cell Biol. Mar 2016] PubMed

Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. [Proc Natl Acad Sci U S A. Mar 2016] PubMed

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Multitasking of the piRNA Silencing Machinery: Targeting Transposable Elements and Foreign Genes in the Bdelloid Rotifer Adineta vaga. [Genetics. Mar 2016] PubMed

Immune responses to endogenous retroelements: taking the bad with the good. [Nat Rev Immunol. Mar 2016] PubMed

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering. [Nat Commun. Mar 2016] PubMed

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Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. [Nature. Feb 2016] PubMed

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Biochemical Characterization of Kat1: a Domesticated hAT-Transposase that Induces DNA Hairpin Formation and MAT-Switching. [Sci Rep. Feb 2016] PubMed

Regulating retrotransposon activity through the use of alternative transcription start sites. [EMBO Rep. Feb 2016] PubMed

Resolving rates of mutation in the brain using single-neuron genomics. [Elife. Feb 2016] PubMed

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High-Throughput Genetic Screens Identify a Large and Diverse Collection of New Sporulation Genes in Bacillus subtilis. [PLoS Biol. Jan 2016] PubMed

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. [Nat Commun. Jan 2016] PubMed

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Genome-Wide Profiling Reveals Remarkable Parallels Between Insertion Site Selcetion Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4+ T Cells. [Mol Ther. Jan 2016] PubMed

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Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins. [Cell. Jan 2016] PubMed

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Ty1-Integrase interacts with RNA Polymerase III specific subcomplexes to promote insertion of Ty1 elements upstream of Pol III-transcribed genes. [J Biol Chem. Jan 2016] PubMed

The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries. [J.Bioinformatics Jan 2016] PubMed

Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha [Mob DNA. Jan 2016] PubMed

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. [Elife. Jan 2016] PubMed

Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline. [Curr Opin Genet Dev. Jan 2016] PubMed

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Systematic identification of factors for provirus silencing in embryonic stem cells. [Cell. Sep 2015] PubMed

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. [PLoS Genet. Dec 2015] PubMed

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A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces. [Curr Genet. Dec 2015] PubMed

Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. [Mob DNA. Dec 2015] PubMed

Comprehensive ex vivo transposon mutagenesis identifies genes that promote growth factor independence and leukemogenesis. [Cancer Res. Dec 2015] PubMed

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VHICA, a new method to discriminate between vertical and horizontal transposon transfer: application to the mariner family within Drosophila. [Mol Biol Evol. Dec 2015] PubMed

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. [PLoS Pathog. Dec 2015] PubMed

piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts. [Nucleic Acids Res. Dec 2015] PubMed

p53 genes function to restrain mobile elements. [Genes Dev. Dec 2015] PubMed

The making of a genomic parasite - the Mothra family sheds light on the evolution of Helitrons in plants. [Mob DNA. Dec 2015] PubMed

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DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes [Mol Biol Evol. Nov 2015] PubMed

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons [PNAS. Nov 2015] PubMed

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HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse [PLoS Genet. Oct 2015] PubMed

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Tools for Targeted Genome Engineering of Established Drosophila Cell Lines [Genetics. Oct 2015] PubMed

Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus [Genetics. Oct 2015] PubMed

The Ty1 Retrotransposon Restriction Factor p22 Targets Gag [PLoS Genet. Oct 2015] PubMed

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Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes [PLoS Genet. Sep 2015] PubMed

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TE-Tracker: systematic identification of transposition events through whole-genome resequencing [BMC Bioinformatics. Nov 2014] PubMed

Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest [Cell. Sep 2015] PubMed

Conformational toggling controls target site choice for the heteromeric transposase element Tn7 [Nucleic Acids Res. Sep 2015] PubMed

Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe [Genetics. Sep 2015] PubMed

Loss of Karma transposon methylation underlies the mantled somaclonal variant of oil palm [Nature. Sep 2015] PubMed

miR-128 represses L1 retrotransposition by binding directly to L1 RNA [Nat Struct Mol Biol. Oct 2015] PubMed

Sequence Analysis and Characterization of Active Human Alu subfamilies Based on the 1000 Genomes Pilot Project [Genome Biol Evol. Aug 2015] PubMed

Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability [DNA Repair Aug 2015] PubMed

Organization and evolution of transposable elements along the bread wheat chromosome 3B [Genome Biology Dec 2014] PubMed

Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions [Genome Biology Dec 2014] PubMed

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma [PNAS Sep 2015] PubMed

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition [Elife. Aug 2015] PubMed

An Atypical AAA+ ATPase Assembly Controls Efficient Transposition through DNA Remodeling and Transposase Recruitment [Cell. Aug 2015] PubMed

Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation [PLoS Genet. Aug 2015] PubMed

piRNAs Are Associated with Diverse Transgenerational Effects on Gene and Transposon Expression in a Hybrid Dysgenic Syndrome of D. virilis [PLoS Genet. Aug 2015] PubMed

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma [Nature Med. Sep 2015] PubMed

MIR retrotransposon sequences provide insulators to the human genome [PNAS. Jul 2015] PubMed

Tn-seq of Caulobacter crescentus under uranium stress reveals genes essential for detoxification and stress tolerance [J Bacteriol. Jul 2015] PubMed

LINE-1 Retroelements Get ZAPped! [PLoS Genet. Jul 2015] PubMed

ZmMBD101 is a DNA binding protein that maintains Mutator elements chromatin in a repressive state in maize [Plant Cell Environ. Jul 2015] PubMed

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation [PLoS Genet. Jul 2015] PubMed

Repbase Update, a database of repetitive elements in eukaryotic genomes [Mobile DNA. Jun 2015] PubMed

The diversification of PHIS transposon superfamily in eukaryotes [Mobile DNA. Jun 2015] PubMed

Distinct sets of PIWI proteins produce arbovirus and transposon-derived piRNAs in Aedes aegypti mosquito cells [Nucleic Acids Res. Jun 2015] PubMed

Structural basis for retroviral integration into nucleosomes [Nature. Jul 2015] PubMed

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery [Curr Opin Genet Dev. Feb 2015] PubMed

A Transposable Element within the Non-canonical Telomerase RNA of Arabidopsis thaliana Telomerase in Response to DNA Damage [PLoS Genet. Jun 2015] PubMed

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination [Genes Dev. Jun 2015] PubMed

The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline [EMBO Rep. Jun 2015] PubMed

Evolution of group II introns [Mobile DNA. Apr 2015] PubMed

N(6)-methyladenine DNA modification in Drosophila [Cell. May 2015] PubMed

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition [PLoS Genet. May 2015] PubMed

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells [Nature. May 2015] PubMed

Rapid quantification of mutant fitness in diverse bacteria by sequencing randomly bar-coded transposons [MBio. May 2015] PubMed

Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production [Science. May 2015] PubMed

Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis [Science. May 2015] PubMed

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes [Sci Rep. May 2015] PubMed

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis [Nat Genet. May 2015] PubMed

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites [Genome Res. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals [Genome Biology. May 2015] PubMed

Mosaic genome of endobacteria in arbuscular mycorrhizal fungi: Transkingdom gene transfer in an ancient mycoplasma-fungus association [PNAS. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses [Genes Dev. Mar 2015] PubMed

Evolution of adaptive immunity from transposable elements combined with innate immune systems [Nat Rev Genet. Mar 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma [Nat Genet. May 2015] PubMed

Phosphorylation of ORF1p is required for L1 retrotransposition [PNAS. Apr 2015] PubMed

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells [Nature. Jun 2015] PubMed

Mobile DNA welcomes new Editors-in-Chief, Marlene Belfort and Haig Kazazian - a BioMed Central blog

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage [Biol Trace Elem Res. Mar 2015] PubMed

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