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  1. Nearly half the human genome consists of repeat elements, most of which are retrotransposons, and many of which play important biological roles. However repeat elements pose several unique challenges to curren...

    Authors: Jason D. Fernandes, Armando Zamudio-Hurtado, Hiram Clawson, W. James Kent, David Haussler, Sofie R. Salama and Maximilian Haeussler

    Citation: Mobile DNA 2020 11:13

    Content type: Software

    Published on:

  2. Mobile elements are ubiquitous components of mammalian genomes and constitute more than half of the human genome. Polymorphic mobile element insertions (pMEIs) are a major source of human genomic variation and...

    Authors: Jui Wan Loh, Hongseok Ha, Timothy Lin, Nawei Sun, Kathleen H. Burns and Jinchuan Xing

    Citation: Mobile DNA 2020 11:12

    Content type: Methodology

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  3. Previously, 3% of the human genome has been annotated as simple sequence repeats (SSRs), similar to the proportion annotated as protein coding. The origin of much of the genome is not well annotated, however, ...

    Authors: Jonathan A. Shortt, Robert P. Ruggiero, Corey Cox, Aaron C. Wacholder and David D. Pollock

    Citation: Mobile DNA 2020 11:11

    Content type: Research

    Published on:

  4. Transposable elements (TEs) are endogenous mutagens and their harmful effects are especially evident in syndromes of hybrid dysgenesis. In Drosophila virilis, hybrid dysgenesis is a syndrome of incomplete gonadal...

    Authors: Lucas W. Hemmer, Guilherme B. Dias, Brittny Smith, Kelley Van Vaerenberghe, Ashley Howard, Casey M. Bergman and Justin P. Blumenstiel

    Citation: Mobile DNA 2020 11:10

    Content type: Research

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  5. The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. The human genome contains ...

    Authors: Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin and Robert Belshaw

    Citation: Mobile DNA 2020 11:9

    Content type: Research

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  6. Chromosome organisation is increasingly recognised as an essential component of genome regulation, cell fate and cell health. Within the realm of transposable elements (TEs) however, the spatial information of...

    Authors: Alexandros Bousios, Hans-Wilhelm Nützmann, Dorothy Buck and Davide Michieletto

    Citation: Mobile DNA 2020 11:8

    Content type: Commentary

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  7. Ligation-mediated PCR protocols have diverse uses including the identification of integration sites of insertional mutagens, integrating vectors and naturally occurring mobile genetic elements. For approaches ...

    Authors: Joanna C. Dawes, Philip Webster, Barbara Iadarola, Claudia Garcia-Diaz, Marian Dore, Bruce J. Bolt, Hamlata Dewchand, Gopuraja Dharmalingam, Alex P. McLatchie, Jakub Kaczor, Juan J. Caceres, Alberto Paccanaro, Laurence Game, Simona Parrinello and Anthony G. Uren

    Citation: Mobile DNA 2020 11:7

    Content type: Methodology

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  8. Endogenous Retroviruses (ERVs) constitute approximately 8% of every human genome and are relics of ancestral infections that affected the germ line cells. The ERV-W group contributed to primate physiology by p...

    Authors: Nicole Grandi, Maria Paola Pisano, Martina Demurtas, Jonas Blomberg, Gkikas Magiorkinis, Jens Mayer and Enzo Tramontano

    Citation: Mobile DNA 2020 11:6

    Content type: Research

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  10. SINEs are a type of nonautonomous retrotransposon that can transpose from one site to be integrated elsewhere in an organism genome. SINE insertion can give rise to genetic variants and regulate gene expressio...

    Authors: Dong Liu, Jinquan Yang, Wenqiao Tang, Xing Zhang, Clay Matthew Royster and Ming Zhang

    Citation: Mobile DNA 2020 11:4

    Content type: Research

    Published on:

  11. Following publication of the original article [1], the authors spotted an error in Table 2.

    Authors: Pavel Jedlicka, Matej Lexa, Ivan Vanat, Roman Hobza and Eduard Kejnovsky

    Citation: Mobile DNA 2020 11:3

    Content type: Correction

    Published on:

    The original article was published in Mobile DNA 2019 10:50

  12. Retrotransposons are one of the oldest evolutionary forces shaping mammalian genomes, with the ability to mobilize from one genomic location to another. This mobilization is also a significant factor in human ...

    Authors: Tiffany Kaul, Maria E. Morales, Alton O. Sartor, Victoria P. Belancio and Prescott Deininger

    Citation: Mobile DNA 2020 11:2

    Content type: Methodology

    Published on:

  13. Long interspersed element-1 (LINE-1, L1) is the major driver of mobile DNA activity in modern humans. When expressed, LINE-1 loci produce bicistronic transcripts encoding two proteins essential for retrotransp...

    Authors: Daniel Ardeljan, Xuya Wang, Mehrnoosh Oghbaie, Martin S. Taylor, David Husband, Vikram Deshpande, Jared P. Steranka, Mikhail Gorbounov, Wan Rou Yang, Brandon Sie, H. Benjamin Larman, Hua Jiang, Kelly R. Molloy, Ilya Altukhov, Zhi Li, Wilson McKerrow…

    Citation: Mobile DNA 2019 11:1

    Content type: Research

    Published on:

  14. Transposable elements (TEs) are an important source of genomic variability in eukaryotic genomes. Their activity impacts genome architecture and gene expression and can lead to drastic phenotypic changes. Ther...

    Authors: Pol Vendrell-Mir, Fabio Barteri, Miriam Merenciano, Josefa González, Josep M. Casacuberta and Raúl Castanera

    Citation: Mobile DNA 2019 10:53

    Content type: Methodology

    Published on:

  15. Sequencing technologies give access to a precise picture of the molecular mechanisms acting upon genome regulation. One of the biggest technical challenges with sequencing data is to map millions of reads to a...

    Authors: Aurélie Teissandier, Nicolas Servant, Emmanuel Barillot and Deborah Bourc’his

    Citation: Mobile DNA 2019 10:52

    Content type: Methodology

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  17. Nesting is common in LTR retrotransposons, especially in large genomes containing a high number of elements.

    Authors: Pavel Jedlicka, Matej Lexa, Ivan Vanat, Roman Hobza and Eduard Kejnovsky

    Citation: Mobile DNA 2019 10:50

    Content type: Research

    Published on:

    The Correction to this article has been published in Mobile DNA 2020 11:3

  20. Miniature inverted repeat transposable elements (MITEs) are small non-autonomous DNA transposons that are ubiquitous in plant genomes, and are mobilised by their autonomous relatives. Stowaway MITEs are derived f...

    Authors: Alicja Macko-Podgórni, Katarzyna Stelmach, Kornelia Kwolek and Dariusz Grzebelus

    Citation: Mobile DNA 2019 10:47

    Content type: Research

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  21. Baboons (genus Papio) and geladas (Theropithecus gelada) are now generally recognized as close phylogenetic relatives, though morphologically quite distinct and generally classified in separate genera. Primate sp...

    Authors: Jerilyn A. Walker, Vallmer E. Jordan, Jessica M. Storer, Cody J. Steely, Paulina Gonzalez-Quiroga, Thomas O. Beckstrom, Lydia C. Rewerts, Corey P. St. Romain, Catherine E. Rockwell, Jeffrey Rogers, Clifford J. Jolly, Miriam K. Konkel and Mark A. Batzer

    Citation: Mobile DNA 2019 10:46

    Content type: Research

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  22. The Tc1/mariner superfamily might represent the most diverse and widely distributed group of DNA transposons. Several families have been identified; however, exploring the diversity of this superfamily and updati...

    Authors: Yatong Sang, Bo Gao, Mohamed Diaby, Wencheng Zong, Cai Chen, Dan Shen, Saisai Wang, Yali Wang, Zoltán Ivics and Chengyi Song

    Citation: Mobile DNA 2019 10:45

    Content type: Research

    Published on:

  23. Unicellular species make up the majority of eukaryotic diversity, however most studies on transposable elements (TEs) have centred on multicellular host species. Such studies may have therefore provided a limi...

    Authors: Jade Southworth, C. Alastair Grace, Alan O. Marron, Nazeefa Fatima and Martin Carr

    Citation: Mobile DNA 2019 10:44

    Content type: Research

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  24. The use of large-scale genomic analyses has resulted in an improvement of transposable element sampling and a significant increase in the number of reported HTT (horizontal transfer of transposable elements) e...

    Authors: Izabella L. Tambones, Annabelle Haudry, Maryanna C. Simão and Claudia M. A. Carareto

    Citation: Mobile DNA 2019 10:43

    Content type: Research

    Published on:

  26. Following publication of the original article [1], the authors reported errors in Table 2 wherein all "KZFP” in the gene names should be changed to “ZNF”.

    Authors: Nicky Chung, G. M. Jonaid, Sophia Quinton, Austin Ross, Corinne E. Sexton, Adrian Alberto, Cody Clymer, Daphnie Churchill, Omar Navarro Leija and Mira V. Han

    Citation: Mobile DNA 2019 10:41

    Content type: Correction

    Published on:

    The original article was published in Mobile DNA 2019 10:39

  27. Transposable elements in prokaryotes are found in many forms and therefore a robust nomenclature system is needed in order to allow researchers to describe and search for them in publications and databases. He...

    Authors: Supathep Tansirichaiya, Md. Ajijur Rahman and Adam P. Roberts

    Citation: Mobile DNA 2019 10:40

    Content type: Review

    Published on:

  28. Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic...

    Authors: Nicky Chung, G. M. Jonaid, Sophia Quinton, Austin Ross, Corinne E. Sexton, Adrian Alberto, Cody Clymer, Daphnie Churchill, Omar Navarro Leija and Mira V. Han

    Citation: Mobile DNA 2019 10:39

    Content type: Research

    Published on:

    The Correction to this article has been published in Mobile DNA 2019 10:41

  29. Henny feathering in chickens is determined by a dominant mutation that transforms male-specific plumage to female-like plumage. Previous studies indicated that this phenotype is caused by ectopic expression in...

    Authors: Jingyi Li, Brian W. Davis, Patric Jern, Ben. J. Dorshorst, Paul B. Siegel and Leif Andersson

    Citation: Mobile DNA 2019 10:38

    Content type: Research

    Published on:

  30. Transposable elements (TEs) can be key drivers of evolution, but the mechanisms and scope of how they impact gene and genome function are largely unknown. Previous analyses revealed that TE-mediated gene ampli...

    Authors: Braham Dhillon, Gert H. J. Kema, Richard C. Hamelin, Burt H. Bluhm and Stephen B. Goodwin

    Citation: Mobile DNA 2019 10:37

    Content type: Research

    Published on:

  31. A considerable portion of the human genome derives from retroviruses inherited over millions of years. Human endogenous retroviruses (HERVs) are usually severely mutated, yet some coding-competent HERVs exist....

    Authors: Giuseppe Rigogliuso, Martin L. Biniossek, John L. Goodier, Bettina Mayer, Gavin C. Pereira, Oliver Schilling, Eckart Meese and Jens Mayer

    Citation: Mobile DNA 2019 10:36

    Content type: Research

    Published on:

  32. Ppmar1 and Ppmar2 are two active mariner-like elements (MLEs) cloned from moso bamboo (Phyllostachys edulis (Carrière) J. Houz) genome possessing transposases that harbour nuclear export signal (NES) domain, but ...

    Authors: Muthusamy Ramakrishnan, Ming-Bing Zhou, Chun-Fang Pan, Heikki Hänninen, Ding-Qin Tang and Kunnummal Kurungara Vinod

    Citation: Mobile DNA 2019 10:35

    Content type: Short report

    Published on:

  33. Kinetoplastids are a flagellated group of protists, including some parasites, such as Trypanosoma and Leishmania species, that can cause diseases in humans and other animals. The genomes of these species enclose ...

    Authors: Yasmin Carla Ribeiro, Lizandra Jaqueline Robe, Danila Syriani Veluza, Cyndia Mara Bezerra dos Santos, Ana Luisa Kalb Lopes, Marco Aurélio Krieger and Adriana Ludwig

    Citation: Mobile DNA 2019 10:34

    Content type: Research

    Published on:

  34. Associations between X-inactive transcript (Xist)–long noncoding RNA (lncRNA) and chromatin are critical intermolecular interactions in the X-chromosome inactivation (XCI) process. Despite high-resolution anal...

    Authors: Yoko Matsuno, Takefumi Yamashita, Michiru Wagatsuma and Hajime Yamakage

    Citation: Mobile DNA 2019 10:33

    Content type: Research

    Published on:

  37. Transposable elements (TEs) are genomic parasites with major impacts on host genome architecture and host adaptation. A proper evaluation of their evolutionary significance has been hampered by the paucity of ...

    Authors: Sylvain Legrand, Thibault Caron, Florian Maumus, Sol Schvartzman, Leandro Quadrana, Eléonore Durand, Sophie Gallina, Maxime Pauwels, Clément Mazoyer, Lucie Huyghe, Vincent Colot, Marc Hanikenne and Vincent Castric

    Citation: Mobile DNA 2019 10:30

    Content type: Research

    Published on:

  39. PIWI-interacting RNAs (piRNAs) are the effectors of transposable element silencing in the reproductive apparatus. In Drosophila ovarian somatic cells, piRNAs arise from long RNA precursors presumably processed wi...

    Authors: Cynthia Dennis, Emilie Brasset and Chantal Vaury

    Citation: Mobile DNA 2019 10:28

    Content type: Research

    Published on:

  42. Helitrons play an important role in shaping eukaryotic genomes due to their ability to transfer horizontally between distantly related species and capture gene fragments during the transposition. However, the mec...

    Authors: Guangjie Han, Nan Zhang, Jian Xu, Heng Jiang, Caihong Ji, Ze Zhang, Qisheng Song, David Stanley, Jichao Fang and Jianjun Wang

    Citation: Mobile DNA 2019 10:25

    Content type: Research

    Published on:

  44. Although most of long interspersed elements (LINEs), one class of non-LTR-retrotransposons, are integrated into the host genome randomely, some elements are retrotransposed into the specific sequences of the g...

    Authors: Azusa Kuroki-Kami, Narisu Nichuguti, Haruka Yatabe, Sayaka Mizuno, Shoji Kawamura and Haruhiko Fujiwara

    Citation: Mobile DNA 2019 10:23

    Content type: Research

    Published on:

  47. Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of t...

    Authors: B. T. Freeman, M. Sokolowski, A. M. Roy-Engel, M. E. Smither and V. P. Belancio

    Citation: Mobile DNA 2019 10:20

    Content type: Research

    Published on:

  48. Retrotransposons are the major determinants of genome sizes and they have shaped both genes and genomes in mammalian organisms, but their overall activity, diversity, and evolution dynamics, particularly their...

    Authors: Cai Chen, Wei Wang, Xiaoyan Wang, Dan Shen, Saisai Wang, Yali Wang, Bo Gao, Klaus Wimmers, Jiude Mao, Kui Li and Chengyi Song

    Citation: Mobile DNA 2019 10:19

    Content type: Research

    Published on:

  49. Conjugative spread of antibiotic resistance and virulence genes in bacteria constitutes an important threat to public health. Beyond the well-known conjugative plasmids, recent genome analyses have shown that ...

    Authors: Nicolas Soler, Emilie Robert, Isaure Chauvot de Beauchêne, Philippe Monteiro, Virginie Libante, Bernard Maigret, Johan Staub, David W. Ritchie, Gérard Guédon, Sophie Payot, Marie-Dominique Devignes and Nathalie Leblond-Bourget

    Citation: Mobile DNA 2019 10:18

    Content type: Research

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  50. Transposable elements (TEs) make up > 50% of the human genome, and the majority of retrotransposon insertions are truncated and many are located in introns. However, the effects of retrotransposition on the ho...

    Authors: Zhuqing Wang, Hayden McSwiggin, Simon J. Newkirk, Yue Wang, Daniel Oliver, Chong Tang, Sandy Lee, Shawn Wang, Shuiqiao Yuan, Huili Zheng, Ping Ye, Wenfeng An and Wei Yan

    Citation: Mobile DNA 2019 10:17

    Content type: Research

    Published on:

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Mobile DNA

ISSN: 1759-8753