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  1. Repeat elements (REs) play important roles for cell function in health and disease. However, RE enrichment analysis in short-read high-throughput sequencing (HTS) data, such as ChIP-seq, is a challenging task.

    Authors: Michel Choudalakis, Pavel Bashtrykov and Albert Jeltsch
    Citation: Mobile DNA 2024 15:6
  2. The genome of the filamentous ascomycete Podospora anserina shows a relatively high abundance of retrotransposons compared to other interspersed repeats. The LTR-retrotransposon family crapaud is particularly abu...

    Authors: Ivar Westerberg, S. Lorena Ament-Velásquez, Aaron A. Vogan and Hanna Johannesson
    Citation: Mobile DNA 2024 15:1
  3. The sixth Japanese meeting on host–transposon interactions, titled “Biological Function and Evolution through Interactions between Hosts and Transposable Elements,” was held on August 24th and 25th, 2023, at t...

    Authors: Kenji Ichiyanagi, Yoko Ikeda and Kuniaki Saito
    Citation: Mobile DNA 2023 14:22
  4. The genomes of many eukaryotes contain DNA repeats in the form of both tandem and interspersed elements with distinct structure, evolutionary histories, and mechanisms of emergence and amplification. Although ...

    Authors: Nikita S. Vassetzky, Sergei A. Kosushkin and Alexey P. Ryskov
    Citation: Mobile DNA 2023 14:21
  5. Despite their origins as selfish parasitic sequences, some transposons in the human genome have been co-opted to serve as regulatory elements, contributing to the evolution of transcriptional networks. Most we...

    Authors: Carmen A. Buttler, Daniel Ramirez, Robin D. Dowell and Edward B. Chuong
    Citation: Mobile DNA 2023 14:20
  6. The conference “Transposable Elements at the Crossroads of Evolution, Health and Disease” was hosted by Keystone Symposia in Whistler, British Columbia, Canada, on September 3–6, 2023, and was organized by Kat...

    Authors: Irina R. Arkhipova, Kathleen H. Burns, Katherine B. Chiappinelli, Edward B. Chuong, Clement Goubert, Alba Guarné, Amanda M. Larracuente, E. Alice Lee and Henry L. Levin
    Citation: Mobile DNA 2023 14:19
  7. In November 2022 the first Dark Genome Symposium was held in Boston, USA. The meeting was hosted by Rome Therapeutics and Enara Bio, two biotechnology companies working on translating our growing understanding...

    Authors: Jef D. Boeke, Kathleen H. Burns, Katherine B. Chiappinelli, Marie Classon, John M. Coffin, Daniel D. DeCarvalho, Joseph D. Dukes, Benjamin Greenbaum, George Kassiotis, Sarah K. Knutson, Arnold J. Levine, Avindra Nath, Sophie Papa, Daniel Rios, John Sedivy and David T. Ting
    Citation: Mobile DNA 2023 14:18
  8. The genome of the obligate biotrophic phytopathogenic barley powdery mildew fungus Blumeria hordei is inflated due to highly abundant and possibly active transposable elements (TEs). In the absence of the otherwi...

    Authors: Jiangzhao Qian, Heba M. M. Ibrahim, Myriam Erz, Florian Kümmel, Ralph Panstruga and Stefan Kusch
    Citation: Mobile DNA 2023 14:17
  9. Repetitive DNA make up a considerable fraction of most eukaryotic genomes. In fish, transposable element (TE) activity has coincided with rapid species diversification. Here, we annotated the repetitive conten...

    Authors: William B. Reinar, Ole K. Tørresen, Alexander J. Nederbragt, Michael Matschiner, Sissel Jentoft and Kjetill S. Jakobsen
    Citation: Mobile DNA 2023 14:14
  10. Long interspersed nuclear element-1 (LINE-1 or L1) comprises 17% of the human genome. As the only autonomous and active retrotransposons, L1 may take part in cancer initiation and progression in some ways. The...

    Authors: Baohong Xu, Xueer Li, Shaoqi Zhang, Meina Lian, Wenbin Huang, Yin Zhang, Yudong Wang and Zhiquan Huang
    Citation: Mobile DNA 2023 14:13
  11. Reverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and highly conserved RNA molecules that serve as key post-transcriptional regul...

    Authors: Rafael L. V. Mercuri, Helena B. Conceição, Gabriela D. A. Guardia, Gabriel Goldstein, Maria D. Vibranovski, Ludwig C. Hinske and Pedro A. F. Galante
    Citation: Mobile DNA 2023 14:12
  12. Accumulating evidence suggests that endogenous retroviruses (ERVs) play an important role in the host response to infection and the development of disease. By analyzing ChIP-sequencing data sets, we show that ...

    Authors: Ankit Arora, Jan Eric Kolberg, Smitha Srinivasachar Badarinarayan, Natalia Savytska, Daksha Munot, Martin Müller, Veronika Krchlíková, Daniel Sauter and Vikas Bansal
    Citation: Mobile DNA 2023 14:11
  13. PIWI-interacting RNAs (piRNAs) are responsible for preventing the movement of transposable elements in germ cells and protect the integrity of germline genomes. In this review, we examine the common elements o...

    Authors: Zuzana Loubalova, Parthena Konstantinidou and Astrid D. Haase
    Citation: Mobile DNA 2023 14:10
  14. Many computational methods have been developed to detect non-reference transposable element (TE) insertions using short-read whole genome sequencing data. The diversity and complexity of such methods often pre...

    Authors: Jingxuan Chen, Preston J. Basting, Shunhua Han, David J. Garfinkel and Casey M. Bergman
    Citation: Mobile DNA 2023 14:8
  15. The strand-biased circularizing integrative elements (SEs) are putatively non-mobilizable integrative elements for transmitting antimicrobial resistance genes. The transposition mode and the prevalence of SEs ...

    Authors: Desmila Idola, Hiroshi Mori, Yuji Nagata, Lisa Nonaka and Hirokazu Yano
    Citation: Mobile DNA 2023 14:7
  16. Patients with systemic lupus erythematosus (SLE) have autoantibodies against the L1-encoded open-reading frame 1 protein (ORF1p). Here, we report (i) which immune cells ORF1p emanates from, (ii) which L1 loci ...

    Authors: Kennedy C. Ukadike, Rayan Najjar, Kathryn Ni, Amanda Laine, Xiaoxing Wang, Alison Bays, Martin S. Taylor, John LaCava and Tomas Mustelin
    Citation: Mobile DNA 2023 14:5
  17. Antimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements....

    Authors: Thanh Quang Tran, Minyoung Park, Jong Eun Lee, Soo Hyun Kim, Jae-Ho Jeong and Hyon E. Choy
    Citation: Mobile DNA 2023 14:4
  18. Canonical telomeres (telomerase-synthetised) are readily forming G-quadruplexes (G4) on the G-rich strand. However, there are examples of non-canonical telomeres among eukaryotes where telomeric tandem repeats...

    Authors: Pavel Jedlička, Viktor Tokan, Iva Kejnovská, Roman Hobza and Eduard Kejnovský
    Citation: Mobile DNA 2023 14:3
  19. DNA transposable elements are mobilized by a “cut and paste” mechanism catalyzed by the binding of one or more transposase proteins to terminal inverted repeats (TIRs) to form a transpositional complex. Study ...

    Authors: Priscilla S. Redd, Stephanie Diaz, David Weidner, Jazmine Benjamin and C. Nathan Hancock
    Citation: Mobile DNA 2023 14:1
  20. Plant, animal and protist genomes often contain endogenous viral elements (EVEs), which correspond to partial and sometimes entire viral genomes that have been captured in the genome of their host organism thr...

    Authors: Héléna Vassilieff, Sana Haddad, Véronique Jamilloux, Nathalie Choisne, Vikas Sharma, Delphine Giraud, Mariène Wan, Saad Serfraz, Andrew D. W. Geering, Pierre-Yves Teycheney and Florian Maumus
    Citation: Mobile DNA 2022 13:31
  21. LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease. Apart from these rare integration events,...

    Authors: Simanti Das, Amanda E. Jones and John M. Abrams
    Citation: Mobile DNA 2022 13:30
  22. Transposable elements (TEs) are selfish DNA sequences capable of moving and amplifying at the expense of host cells. Despite this, an increasing number of studies have revealed that TE proteins are important c...

    Authors: Dragomira N. Markova, Fatema B. Ruma, Claudio Casola, Ayda Mirsalehi and Esther Betrán
    Citation: Mobile DNA 2022 13:28
  23. Transposable elements are ubiquitous and play a fundamental role in shaping genomes during evolution. Since excessive transposition can be mutagenic, mechanisms exist in the cells to keep these mobile elements...

    Authors: Anastasia Barkova, Indranil Adhya, Christine Conesa, Amna Asif-Laidin, Amandine Bonnet, Elise Rabut, Carine Chagneau, Pascale Lesage and Joël Acker
    Citation: Mobile DNA 2022 13:26
  24. Krüppel Associated Box-containing Zinc Finger Proteins (KRAB-ZFPs), representing the largest superfamily of transcription factors in mammals, are predicted to primarily target and repress transposable elements...

    Authors: Yang Zhang, Fei He, Yanning Zhang, Qian Dai, Qintong Li, Jing Nan, Ruidong Miao and Bo Cheng
    Citation: Mobile DNA 2022 13:25
  25. Mobile group I introns encode homing endonucleases that confer intron mobility initiated by a double-strand break in the intron-lacking allele at the site of insertion. Nuclear ribosomal DNA of some fungi and ...

    Authors: Kjersti Lian, Betty M. N. Furulund, Anders A. Tveita, Peik Haugen and Steinar D. Johansen
    Citation: Mobile DNA 2022 13:23
  26. Bats are a major reservoir of zoonotic viruses, and there has been growing interest in characterizing bat-specific features of innate immunity and inflammation. Recent studies have revealed bat-specific adapta...

    Authors: Giulia Irene Maria Pasquesi, Conor J. Kelly, Andrea D. Ordonez and Edward B. Chuong
    Citation: Mobile DNA 2022 13:22
  27. Endogenous expression of L1 mRNA is the first step in an L1-initiated mutagenesis event. However, the contribution of individual cell types to patterns of organ-specific L1 mRNA expression remains poorly under...

    Authors: Emily C. Stow, Melody Baddoo, Alexis J. LaRosa, Dawn LaCoste, Prescott Deininger and Victoria Belancio
    Citation: Mobile DNA 2022 13:21
  28. ICEs are mobile genetic elements found integrated into bacterial chromosomes that can excise and be transferred to a new cell. They play an important role in horizontal gene transmission and carry accessory ge...

    Authors: Jéssica Catarine Silva de Assis, Osiel Silva Gonçalves, Alexia Suellen Fernandes, Marisa Vieira de Queiroz, Denise Mara Soares Bazzolli and Mateus Ferreira Santana
    Citation: Mobile DNA 2022 13:19
  29. Long terminal repeat retrotransposons (LTR-RTs) make up a considerable portion of plant genomes. New insertions of these active LTR-RTs modify gene structures and functions and play an important role in genome...

    Authors: Hyunjin Koo, Soomin Kim, Hyun-Seung Park, Sang-Ji Lee, Nam-Chon Paek, Jungnam Cho and Tae-Jin Yang
    Citation: Mobile DNA 2022 13:18
  30. Transposable element (TE) transcription is a precursor to its mobilisation in host genomes. However, the characteristics of expressed TE loci, the identification of self-competent transposon loci contributing ...

    Authors: Ting-Hsuan Chen and Christopher Winefield
    Citation: Mobile DNA 2022 13:16
  31. Transposable elements (TEs) are major genomic components in most eukaryotic genomes and play an important role in genome evolution. However, despite their relevance the identification of TEs is not an easy tas...

    Authors: Matias Rodriguez and Wojciech Makałowski
    Citation: Mobile DNA 2022 13:14
  32. The internal promoter in L1 5’UTR is critical for autonomous L1 transcription and initiating retrotransposition. Unlike the human genome, which features one contemporarily active subfamily, four subfamilies (A...

    Authors: Lingqi Kong, Karabi Saha, Yuchi Hu, Jada N. Tschetter, Chase E. Habben, Leanne S. Whitmore, Changfeng Yao, Xijin Ge, Ping Ye, Simon J. Newkirk and Wenfeng An
    Citation: Mobile DNA 2022 13:13
  33. Whiteflies are agricultural pests that cause negative impacts globally to crop yields resulting at times in severe economic losses and food insecurity. The Bemisia tabaci whitefly species complex is the most dama...

    Authors: Juan Paolo A. Sicat, Paul Visendi, Steven O. Sewe, Sophie Bouvaine and Susan E. Seal
    Citation: Mobile DNA 2022 13:12

    The Correction to this article has been published in Mobile DNA 2022 13:17

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