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  1. Content type: Research

    Twin-ribozyme introns represent a complex class of mobile group I introns that harbour a lariat capping (LC) ribozyme and a homing endonuclease gene embedded in a conventional self-splicing group I ribozyme (G...

    Authors: Yunjia Tang, Henrik Nielsen, Benoît Masquida, Paul P Gardner and Steinar D Johansen

    Citation: Mobile DNA 2014 5:25

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  2. Content type: Research

    CACTA elements are DNA transposons and are found in numerous organisms. Despite their low activity, several thousand copies can be identified in many genomes. CACTA elements transpose using a ‘cut-and-paste’ mech...

    Authors: Jan P Buchmann, Ari Löytynoja, Thomas Wicker and Alan H Schulman

    Citation: Mobile DNA 2014 5:24

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  3. Content type: Review

    Transposable elements (TEs) are major structural components of eukaryotic genomes; however, mobilization of TEs generally has negative effects on the host genome. To counteract this threat, host cells have evo...

    Authors: Soichiro Yamanaka, Mikiko C Siomi and Haruhiko Siomi

    Citation: Mobile DNA 2014 5:22

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  4. Content type: Research

    Bari-like transposons belong to the Tc1-mariner superfamily, and they have been identified in several genomes of the Drosophila genus. This transposon’s family has been used as paradigm to investigate the complex...

    Authors: Antonio Palazzo, Roberta Moschetti, Ruggiero Caizzi and René Massimiliano Marsano

    Citation: Mobile DNA 2014 5:21

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  5. Content type: Commentary

    Processed pseudogenes are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome using the enzymatic activities of active L1 elements. Processed pseudogenes generally...

    Authors: Haig H Kazazian Jr

    Citation: Mobile DNA 2014 5:20

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  6. Content type: Opinion

    During the Mobile Genetic Elements and Genome Evolution Keystone Symposium in March 2014, the Editors of Mobile DNA caught up with a panel of conference speakers to select key advances in the field, and hear thei...

    Authors: Marlene Belfort, Luciano Marraffini, Todd Macfarlan, Jef Boeke, Keith Slotkin, Harmit Malik and Lynne Maquat

    Citation: Mobile DNA 2014 5:16

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  7. Content type: Research

    The Drosophila INterspersed Elements-1 (DINE-1/INE1) transposable elements (TEs) are the most abundant component of the Drosophila melanogaster genome and have been associated with functional gene duplications. D...

    Authors: Jainy Thomas, Komal Vadnagara and Ellen J Pritham

    Citation: Mobile DNA 2014 5:18

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  8. Content type: Research

    The Tc1/mariner superfamily of transposable elements (TEs) is widespread in animal genomes. Mariner-like elements, which bear a DDD triad catalytic motif, have been identified in a wide range of flowering plant s...

    Authors: Yuan Liu and Guojun Yang

    Citation: Mobile DNA 2014 5:17

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  9. Content type: Research

    Mammalian-wide interspersed repeats (MIRs) are the most ancient family of transposable elements (TEs) in the human genome. The deep conservation of MIRs initially suggested the possibility that they had been e...

    Authors: Daudi Jjingo, Andrew B Conley, Jianrong Wang, Leonardo Mariño-Ramírez, Victoria V Lunyak and I King Jordan

    Citation: Mobile DNA 2014 5:14

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  10. Content type: Research

    Trichomonas vaginalis is the most prevalent non-viral sexually transmitted parasite. Although the protist is presumed to reproduce asexually, 60% of its haploid genome contains transposable elements (TEs), known ...

    Authors: Martina Bradic, Sally D Warring, Vivien Low and Jane M Carlton

    Citation: Mobile DNA 2014 5:12

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  11. Content type: Commentary

    LINE-1s (L1s), the only currently active autonomous mobile DNA in humans, occupy at least 17% of human DNA. Throughout evolution, the L1 has also been responsible for genomic insertion of thousands of processe...

    Authors: John L Goodier

    Citation: Mobile DNA 2014 5:11

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  12. Content type: Research

    Tos17 was the first LTR retrotransposon (Copia) described as active in cultivated rice, and is present in two copies in the genome of the sequenced Nipponbare variety. Only the chromosome 7 copy is active and abl...

    Authors: Francois Sabot

    Citation: Mobile DNA 2014 5:10

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  13. Content type: Review

    Group I introns are intervening sequences that have invaded tRNA, rRNA and protein coding genes in bacteria and their phages. The ability of group I introns to self-splice from their host transcripts, by actin...

    Authors: Georg Hausner, Mohamed Hafez and David R Edgell

    Citation: Mobile DNA 2014 5:8

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  14. Content type: Reviewer Acknowledgement

    The Editors of Mobile DNA would like to thank all our reviewers who have contributed to the journal in volume 4 (2013).

    Authors: Nancy L Craig, Thomas H Eickbush, Cédric Feschotte and Henry L Levin

    Citation: Mobile DNA 2014 5:3

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  15. Content type: Research

    Hybrid dysgenic syndromes in Drosophila have been critical for characterizing host mechanisms of transposable element (TE) regulation. This is because a common feature of hybrid dysgenesis is germline TE mobiliza...

    Authors: Justin P Blumenstiel

    Citation: Mobile DNA 2014 5:6

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  16. Content type: Research

    Horizontal transfer of transposable elements (HTT) is increasingly appreciated as an important source of genome and species evolution in eukaryotes. However, our understanding of HTT dynamics is still poor in ...

    Authors: Mathilde Dupeyron, Sébastien Leclercq, Nicolas Cerveau, Didier Bouchon and Clément Gilbert

    Citation: Mobile DNA 2014 5:4

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  17. Content type: Review

    Mobile group II introns are bacterial retrotransposons that combine the activities of an autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert site-specifically into DNA. ...

    Authors: Peter J Enyeart, Georg Mohr, Andrew D Ellington and Alan M Lambowitz

    Citation: Mobile DNA 2014 5:2

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  18. Content type: Research

    Transposable elements (TEs) play a major role in genome evolution. Their capacity to move and/or multiply in the genome of their host may have profound impacts on phenotypes and dramatic consequences on genome...

    Authors: Roland Vergilino, Shannon HC Eagle, Teresa J Crease and France Dufresne

    Citation: Mobile DNA 2014 5:1

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  19. Content type: Software

    Accurate and complete identification of mobile elements is a challenging task in the current era of sequencing, given their large numbers and frequent truncations. Group II intron retroelements, which consist ...

    Authors: Michael Abebe, Manuel A Candales, Adrian Duong, Keyar S Hood, Tony Li, Ryan A E Neufeld, Abat Shakenov, Runda Sun, Li Wu, Ashley M Jarding, Cameron Semper and Steven Zimmerly

    Citation: Mobile DNA 2013 4:28

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  20. Content type: Research

    Research into great ape genomes has revealed widely divergent activity levels over time for Alu elements. However, the diversity of this mobile element family in the genome of the western lowland gorilla has prev...

    Authors: Adam T McLain, Glenn W Carman, Mitchell L Fullerton, Thomas O Beckstrom, William Gensler, Thomas J Meyer, Christopher Faulk and Mark A Batzer

    Citation: Mobile DNA 2013 4:26

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  21. Content type: Research

    piggyBac domain (PGBD) transposons are found in organisms ranging from fungi to humans. Three domesticated piggyBac elements have been described. In the ciliates Paramecium tetraurelia and Tetrahymena thermophila

    Authors: Thomas Pavelitz, Lucas T Gray, Stephanie L Padilla, Arnold D Bailey and Alan M Weiner

    Citation: Mobile DNA 2013 4:23

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  22. Content type: Research

    Hematolymphoid neoplasms frequently harbor recurrent genetic abnormalities. Some of the most well recognized lesions are chromosomal translocations, and many of these are known to play pivotal roles in pathoge...

    Authors: Nemanja Rodić, John G Zampella, Toby C Cornish, Sarah J Wheelan and Kathleen H Burns

    Citation: Mobile DNA 2013 4:22

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  23. Content type: Research

    Transposable elements (TEs) have the potential to impact genome structure, function and evolution in profound ways. In order to understand the contribution of transposable elements (TEs) to Heliconius melpomene, ...

    Authors: Christine A Lavoie, Roy N Platt II, Peter A Novick, Brian A Counterman and David A Ray

    Citation: Mobile DNA 2013 4:21

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  24. Content type: Research

    Only a few transposable elements are known to exhibit site-specific insertion patterns, including the well-studied R-element retrotransposons that insert into specific sites within the multigene rDNA. The only...

    Authors: Tyler A Elliott, Deborah E Stage, Teresa J Crease and Thomas H Eickbush

    Citation: Mobile DNA 2013 4:20

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  25. Content type: Research

    Penelope-like elements (PLEs) are an enigmatic group of retroelements sharing a common ancestor with telomerase reverse transcriptases. In our previous studies, we identified endonuclease-deficient PLEs that are ...

    Authors: Irina R Arkhipova, Irina A Yushenova and Fernando Rodriguez

    Citation: Mobile DNA 2013 4:19

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  26. Content type: Research

    Telomere maintenance in Drosophila relies on the targeted transposition of three very special non-LTR retrotransposons, HeT-A, TART, and TAHRE (HTT). The sequences of the retrotransposon array build up the telome...

    Authors: Rute Silva-Sousa, Míriam Díaz Varela and Elena Casacuberta

    Citation: Mobile DNA 2013 4:18

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  27. Content type: Review

    Group I introns are a distinct class of RNA self-splicing introns with an ancient origin. All known group I introns present in eukaryote nuclei interrupt functional ribosomal RNA genes located in ribosomal DNA...

    Authors: Annica Hedberg and Steinar D Johansen

    Citation: Mobile DNA 2013 4:17

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  28. Content type: Short Report

    The non-long terminal repeat (non-LTR) retrotransposons, long interspersed element-1 (LINE-1) and Alu are currently active retroelements in humans. We, and others, have observed that different populations of H...

    Authors: Vincent A Streva, Zachary J Faber and Prescott L Deininger

    Citation: Mobile DNA 2013 4:16

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  29. Content type: Short Report

    Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) co...

    Authors: Yi Xie, Lajos Mates, Zoltán Ivics, Zsuzsanna Izsvák, Sandra L Martin and Wenfeng An

    Citation: Mobile DNA 2013 4:10

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  30. Content type: Research

    Chromoviruses are one of the three genera of Ty3-gypsy long terminal repeat (LTR) retrotransposons, and are present in high copy numbers in plant genomes. They are widely distributed within the plant kingdom, wit...

    Authors: Beatrice Weber, Tony Heitkam, Daniela Holtgräwe, Bernd Weisshaar, André E Minoche, Juliane C Dohm, Heinz Himmelbauer and Thomas Schmidt

    Citation: Mobile DNA 2013 4:8

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  31. Content type: Reviewer Acknowledgement

    The editors of Mobile DNA would like to thank all our reviewers who have contributed to the journal in volume 3 (2012).

    Authors: Nancy L Craig, Thomas H Eikbush and Daniel F Voytas

    Citation: Mobile DNA 2013 4:4

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  32. Content type: Research

    Transposable elements play a major role in genome evolution. Their capacity to move and/or multiply in the genome of their host may have profound impacts on phenotypes, and may have dramatic consequences on ge...

    Authors: Roland Vergilino, Tyler A Elliott, Philippe Desjardins-Proulx, Teresa J Crease and France Dufresne

    Citation: Mobile DNA 2013 4:7

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  33. Content type: Research

    Galileo is a transposable element responsible for the generation of three chromosomal inversions in natural populations of Drosophila buzzatii. Although the most characteristic feature of Galileo is the long inte...

    Authors: Mar Marzo, Xabier Bello, Marta Puig, Xulio Maside and Alfredo Ruiz

    Citation: Mobile DNA 2013 4:6

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