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  3. Transposable elements (TEs) are genomic parasites with major impacts on host genome architecture and host adaptation. A proper evaluation of their evolutionary significance has been hampered by the paucity of ...

    Authors: Sylvain Legrand, Thibault Caron, Florian Maumus, Sol Schvartzman, Leandro Quadrana, Eléonore Durand, Sophie Gallina, Maxime Pauwels, Clément Mazoyer, Lucie Huyghe, Vincent Colot, Marc Hanikenne and Vincent Castric
    Citation: Mobile DNA 2019 10:30
    Content type: Research Published on:

  5. PIWI-interacting RNAs (piRNAs) are the effectors of transposable element silencing in the reproductive apparatus. In Drosophila ovarian somatic cells, piRNAs arise from long RNA precursors presumably processed wi...

    Authors: Cynthia Dennis, Emilie Brasset and Chantal Vaury
    Citation: Mobile DNA 2019 10:28
    Content type: Research Published on:

  8. Helitrons play an important role in shaping eukaryotic genomes due to their ability to transfer horizontally between distantly related species and capture gene fragments during the transposition. However, the mec...

    Authors: Guangjie Han, Nan Zhang, Jian Xu, Heng Jiang, Caihong Ji, Ze Zhang, Qisheng Song, David Stanley, Jichao Fang and Jianjun Wang
    Citation: Mobile DNA 2019 10:25
    Content type: Research Published on:

  10. Although most of long interspersed elements (LINEs), one class of non-LTR-retrotransposons, are integrated into the host genome randomely, some elements are retrotransposed into the specific sequences of the g...

    Authors: Azusa Kuroki-Kami, Narisu Nichuguti, Haruka Yatabe, Sayaka Mizuno, Shoji Kawamura and Haruhiko Fujiwara
    Citation: Mobile DNA 2019 10:23
    Content type: Research Published on:

  13. Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of t...

    Authors: B. T. Freeman, M. Sokolowski, A. M. Roy-Engel, M. E. Smither and V. P. Belancio
    Citation: Mobile DNA 2019 10:20
    Content type: Research Published on:

  14. Retrotransposons are the major determinants of genome sizes and they have shaped both genes and genomes in mammalian organisms, but their overall activity, diversity, and evolution dynamics, particularly their...

    Authors: Cai Chen, Wei Wang, Xiaoyan Wang, Dan Shen, Saisai Wang, Yali Wang, Bo Gao, Klaus Wimmers, Jiude Mao, Kui Li and Chengyi Song
    Citation: Mobile DNA 2019 10:19
    Content type: Research Published on:

  15. Conjugative spread of antibiotic resistance and virulence genes in bacteria constitutes an important threat to public health. Beyond the well-known conjugative plasmids, recent genome analyses have shown that ...

    Authors: Nicolas Soler, Emilie Robert, Isaure Chauvot de Beauchêne, Philippe Monteiro, Virginie Libante, Bernard Maigret, Johan Staub, David W. Ritchie, Gérard Guédon, Sophie Payot, Marie-Dominique Devignes and Nathalie Leblond-Bourget
    Citation: Mobile DNA 2019 10:18
    Content type: Research Published on:

  16. Transposable elements (TEs) make up > 50% of the human genome, and the majority of retrotransposon insertions are truncated and many are located in introns. However, the effects of retrotransposition on the ho...

    Authors: Zhuqing Wang, Hayden McSwiggin, Simon J. Newkirk, Yue Wang, Daniel Oliver, Chong Tang, Sandy Lee, Shawn Wang, Shuiqiao Yuan, Huili Zheng, Ping Ye, Wenfeng An and Wei Yan
    Citation: Mobile DNA 2019 10:17
    Content type: Research Published on:

  17. Transposable elements (TE) are commonly regarded as “junk DNA” with no apparent regulatory roles in the human genome. However, a growing body of evidence demonstrates that some TEs exhibit regulatory activitie...

    Authors: Jiayue-Clara Jiang and Kyle R. Upton
    Citation: Mobile DNA 2019 10:16
    Content type: Research Published on:

  18. Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape i...

    Authors: Liane Gagnier, Victoria P. Belancio and Dixie L. Mager
    Citation: Mobile DNA 2019 10:15
    Content type: Review Published on:

  20. We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak core-promoter motifs make these promoters, that we hav...

    Authors: Antonio Palazzo, Patrizio Lorusso, Csaba Miskey, Oliver Walisko, Andrea Gerbino, Carlo Marya Thomas Marobbio, Zoltán Ivics and René Massimiliano Marsano
    Citation: Mobile DNA 2019 10:13
    Content type: Research Published on:

  23. Transposable elements (TEs) are not randomly distributed in the genome. A genome-wide analysis of the D. melanogaster genome found that differences in TE density across 50 kb genomic regions was due both to trans...

    Authors: Miriam Merenciano, Camillo Iacometti and Josefa González
    Citation: Mobile DNA 2019 10:10
    Content type: Short report Published on:

  24. Human stem cells harbor significant potential for basic and clinical translational research as well as regenerative medicine. Currently ~ 3000 adult and ~ 30 pluripotent stem cell-based, interventional clinica...

    Authors: Gerald G. Schumann, Nina V. Fuchs, Pablo Tristán-Ramos, Attila Sebe, Zoltán Ivics and Sara R. Heras
    Citation: Mobile DNA 2019 10:9
    Content type: Review Published on:

  25. Transposable elements make up a significant portion of the human genome. Accurately locating these mobile DNAs is vital to understand their role as a source of structural variation and somatic mutation. To thi...

    Authors: Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke and Kathleen H. Burns
    Citation: Mobile DNA 2019 10:8
    Content type: Methodology Published on:

  26. Pseudomonas syringae is a γ-proteobacterium causing economically relevant diseases in practically all cultivated plants. Most isolates of this pathogen contain native plasmids collectively carrying many pathogeni...

    Authors: Leire Bardaji, Maite Añorga, Myriam Echeverría, Cayo Ramos and Jesús Murillo
    Citation: Mobile DNA 2019 10:7
    Content type: Research Published on:

  27. Thanks to their ability to move around and replicate within genomes, transposable elements (TEs) are perhaps the most important contributors to genome plasticity and evolution. Their detection and annotation a...

    Authors: Joëlle Amselem, Guillaume Cornut, Nathalie Choisne, Michael Alaux, Françoise Alfama-Depauw, Véronique Jamilloux, Florian Maumus, Thomas Letellier, Isabelle Luyten, Cyril Pommier, Anne-Françoise Adam-Blondon and Hadi Quesneville
    Citation: Mobile DNA 2019 10:6
    Content type: Software Published on:

  29. The transfer of genetic material from non-parent organisms is called horizontal gene transfer (HGT). One of the most conclusive cases of HGT in metazoans was previously described for the cellulose synthase gen...

    Authors: Maria A. Daugavet, Sergey Shabelnikov, Alexander Shumeev, Tatiana Shaposhnikova, Leonid S. Adonin and Olga Podgornaya
    Citation: Mobile DNA 2019 10:4
    Content type: Research Published on:

  30. Repetitive sequences, including transposable elements (TEs) and satellite DNAs, occupy a considerable portion of plant genomes. Analysis of the repeat fraction benefits the understanding of genome structure an...

    Authors: Shu-Fen Li, Yu-Jiao Guo, Jia-Rong Li, Dong-Xu Zhang, Bing-Xiao Wang, Ning Li, Chuan-Liang Deng and Wu-Jun Gao
    Citation: Mobile DNA 2019 10:3
    Content type: Research Published on:

  31. The original article [1] contained an error whereby author Dong Yin’s name was mistakenly inverted. This error has now been corrected.

    Authors: Kaishun Hu, Yu Li, Wenjing Wu, Hengxing Chen, Zhen Chen, Yin Zhang, Yabin Guo and Dong Yin
    Citation: Mobile DNA 2019 10:2
    Content type: Correction Published on:

    The original article was published in Mobile DNA 2018 9:33

  32. Plant LTR-retrotransposons are classified into two superfamilies, Ty1/copia and Ty3/gypsy. They are further divided into an enormous number of families which are, due to the high diversity of their nucleotide ...

    Authors: Pavel Neumann, Petr Novák, Nina Hoštáková and Jiří Macas
    Citation: Mobile DNA 2019 10:1
    Content type: Research Published on:

  33. The evolution and spread of antibiotic resistance is often mediated by mobile genetic elements. Integrative and conjugative elements (ICEs) are the most abundant conjugative elements among prokaryotes. However...

    Authors: João Botelho, Adam P. Roberts, Ricardo León-Sampedro, Filipa Grosso and Luísa Peixe
    Citation: Mobile DNA 2018 9:37
    Content type: Research Published on:

  35. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving loss of motor neurons and having no known cure and uncertain etiology. Several studies have drawn connections between altered ...

    Authors: Gavin C. Pereira, Laura Sanchez, Paul M. Schaughency, Alejandro Rubio-Roldán, Jungbin A. Choi, Evarist Planet, Ranjan Batra, Priscilla Turelli, Didier Trono, Lyle W. Ostrow, John Ravits, Haig H. Kazazian, Sarah J. Wheelan, Sara R. Heras, Jens Mayer, Jose Luis García-Pérez…
    Citation: Mobile DNA 2018 9:35
    Content type: Research Published on:

  37. Similar to retro−/lenti- virus system, DNA transposons are useful tools for stable expression of exogenous genes in mammalian cells. Sleeping Beauty (SB) transposon has adopted for integrating genes into host ...

    Authors: Kaishun Hu, Yu Li, Wenjing Wu, Hengxing Chen, Zhen Chen, Yin Zhang, Yabin Guo and Dong Yin
    Citation: Mobile DNA 2018 9:33
    Content type: Research Published on:

    The Correction to this article has been published in Mobile DNA 2019 10:2

  38. Although repeat sequences constitute about 37% of carnivore genomes, the characteristics and distribution of repeat sequences among carnivore genomes have not been fully investigated. Based on the updated Repb...

    Authors: Changjun Peng, Lili Niu, Jiabo Deng, Jianqiu Yu, Xueyan Zhang, Chuang Zhou, Jinchuan Xing and Jing Li
    Citation: Mobile DNA 2018 9:32
    Content type: Research Published on:

  39. There is increasing evidence that the transpositional activity of retroelements (REs) is not limited to germ line cells, but often occurs in tumor and normal somatic cells. Somatic transpositions were found in...

    Authors: Alexander Y. Komkov, Anastasia A. Minervina, Gaiaz A. Nugmanov, Mariia V. Saliutina, Konstantin V. Khodosevich, Yuri B. Lebedev and Ilgar Z. Mamedov
    Citation: Mobile DNA 2018 9:31
    Content type: Methodology Published on:

  42. Transposable elements are biologically important components of eukaryote genomes. In particular, non-LTR retrotransposons (N-LTRrs) played a key role in shaping the human genome throughout evolution. In this s...

    Authors: Etienne Guichard, Valentina Peona, Guidantonio Malagoli Tagliazucchi, Lucia Abitante, Evelyn Jagoda, Margherita Musella, Marco Ricci, Alejandro Rubio-Roldán, Stefania Sarno, Donata Luiselli, Davide Pettener, Cristian Taccioli, Luca Pagani, Jose Luis Garcia-Perez and Alessio Boattini
    Citation: Mobile DNA 2018 9:28
    Content type: Research Published on:

  44. The antisense insertion of a canine short interspersed element (SINEC_Cf) in the pigmentation gene PMEL (or SILV) causes a coat pattern phenotype in dogs termed merle. Merle is a semi-dominant trait characterized...

    Authors: Sarah C. Murphy, Jacquelyn M. Evans, Kate L. Tsai and Leigh Anne Clark
    Citation: Mobile DNA 2018 9:26
    Content type: Research Published on:

  45. The field of small RNA is one of the most investigated research areas since they were shown to regulate transposable elements and gene expression and play essential roles in fundamental biological processes. S...

    Authors: Romain Pogorelcnik, Chantal Vaury, Pierre Pouchin, Silke Jensen and Emilie Brasset
    Citation: Mobile DNA 2018 9:25
    Content type: Software Published on:

  46. Homing endonuclease genes (HEGs) are widely distributed genetic elements in the mitochondrial genomes of a diversity of eukaryotes. Due to their ability to self-propagate within and between genomes, these elem...

    Authors: Zhun Yan, Zhimin Li, Li Yan, Yongting Yu, Yi Cheng, Jia Chen, Yunyun Liu, Chunsheng Gao, Liangbin Zeng, Xiangping Sun, Litao Guo and Jianping Xu
    Citation: Mobile DNA 2018 9:24
    Content type: Research Published on:

  47. The majority of Eukaryotic genomes are composed of a small portion of stable (non-mobile) genes and a large fraction of parasitic mobile elements such as transposable elements and endogenous viruses: the Mobil...

    Authors: Alexandre Freitas da Silva, Filipe Zimmer Dezordi, Elgion Lucio Silva Loreto and Gabriel Luz Wallau
    Citation: Mobile DNA 2018 9:23
    Content type: Research Published on:

  48. Retrotransposons are transposable elements (TEs) capable of “jumping” in germ, embryonic and tumor cells and, as is now clearly established, in the neuronal lineage. Mosaic TE insertions form part of a broader...

    Authors: Geoffrey J. Faulkner and Victor Billon
    Citation: Mobile DNA 2018 9:22
    Content type: Review Published on:

  49. The Mobile Genetic Elements and Genome Plasticity conference was hosted by Keystone Symposia in Santa Fe, NM USA, February 11–15, 2018. The organizers were Marlene Belfort, Evan Eichler, Henry Levin and Lynne ...

    Authors: John M. Abrams, Irina R. Arkhipova, Marlene Belfort, Jef D. Boeke, M. Joan Curcio, Geoffrey J. Faulkner, John L. Goodier, Ruth Lehmann and Henry L. Levin
    Citation: Mobile DNA 2018 9:21
    Content type: Meeting report Published on:
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ISSN: 1759-8753