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  1. Content type: Review

    Tandem C2H2-type zinc finger proteins (ZFPs) constitute the largest transcription factor family in animals. Tandem-ZFPs bind DNA in a sequence-specific manner through arrays of multiple zinc finger domains tha...

    Authors: Gernot Wolf, David Greenberg and Todd S. Macfarlan

    Citation: Mobile DNA 2015 6:17

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  2. Content type: Research

    The discovery of many fragments of viral genomes integrated in the genome of their eukaryotic host (endogenous viral elements; EVEs) has recently opened new avenues to further our understanding of viral evolut...

    Authors: Gabriel Metegnier, Thomas Becking, Mohamed Amine Chebbi, Isabelle Giraud, Bouziane Moumen, Sarah Schaack, Richard Cordaux and Clément Gilbert

    Citation: Mobile DNA 2015 6:16

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  3. Content type: Research

    A key difference between the Tourist and Stowaway families of miniature inverted repeat transposable elements (MITEs) is the manner in which their excision alters the genome. Upon excision, Stowaway-like MITEs an...

    Authors: David M. Gilbert, M. Catherine Bridges, Ashley E. Strother, Courtney E. Burckhalter, James M. Burnette III and C. Nathan Hancock

    Citation: Mobile DNA 2015 6:15

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  4. Content type: Research

    In the compact and haploid genome of Dictyostelium discoideum control of transposon activity is of particular importance to maintain viability. The non-long terminal repeat retrotransposon TRE5-A amplifies contin...

    Authors: Anika Schmith, Thomas Spaller, Friedemann Gaube, Åsa Fransson, Benjamin Boesler, Sandeep Ojha, Wolfgang Nellen, Christian Hammann, Fredrik Söderbom and Thomas Winckler

    Citation: Mobile DNA 2015 6:14

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  5. Content type: Commentary

    DNA derived from transposable elements (TEs) constitutes large parts of the genomes of complex eukaryotes, with major impacts not only on genomic research but also on how organisms evolve and function. Althoug...

    Authors: Douglas R. Hoen, Glenn Hickey, Guillaume Bourque, Josep Casacuberta, Richard Cordaux, Cédric Feschotte, Anna-Sophie Fiston-Lavier, Aurélie Hua-Van, Robert Hubley, Aurélie Kapusta, Emmanuelle Lerat, Florian Maumus, David D. Pollock, Hadi Quesneville, Arian Smit, Travis J. Wheeler…

    Citation: Mobile DNA 2015 6:13

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  6. Content type: Research

    PHIS transposon superfamily belongs to DNA transposons and includes PIF/Harbinger, ISL2EU, and Spy transposon groups. These three groups have similar DDE domain-containing transposases; however, their coding capa...

    Authors: Min-Jin Han, Chu-Lin Xiong, Hong-Bo Zhang, Meng-Qiang Zhang, Hua-Hao Zhang and Ze Zhang

    Citation: Mobile DNA 2015 6:12

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  7. Content type: Research

    Short interspersed elements (SINEs) have a powerful influence on genome evolution and can be useful markers for phylogenetic inference and population genetic analyses. In this study, we examined survey sequenc...

    Authors: David A Ray, Heidi JT Pagan, Roy N Platt II, Ashley R Kroll, Sarah Schaack and Richard D Stevens

    Citation: Mobile DNA 2015 6:10

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  8. Content type: Review

    Present in the genomes of bacteria and eukaryotic organelles, group II introns are an ancient class of ribozymes and retroelements that are believed to have been the ancestors of nuclear pre-mRNA introns. Desp...

    Authors: Steven Zimmerly and Cameron Semper

    Citation: Mobile DNA 2015 6:7

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  9. Content type: Reviewer acknowledgement

    The Editors of Mobile DNA would like to thank all our reviewers who have contributed to the journal in volume 5 (2014).

    Authors: Nancy L Craig, Thomas H Eikbush, Cédric Feschotte and Henry Levin

    Citation: Mobile DNA 2015 6:6

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  10. Content type: Research

    Human endogenous retroviruses of the HERV-K(HML-2) group have been associated with the development of tumor diseases. Various HERV-K(HML-2) loci encode retrovirus-like proteins, and expression of such proteins...

    Authors: Katja Schmitt, Kristina Heyne, Klaus Roemer, Eckart Meese and Jens Mayer

    Citation: Mobile DNA 2015 6:4

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  11. Content type: Research

    The active human mobile element, long interspersed element 1 (L1) currently populates human genomes in excess of 500,000 copies per haploid genome. Through its mobility via a process called target primed rever...

    Authors: Travis B White, Adam M McCoy, Vincent A Streva, Joshua Fenrich and Prescott L Deininger

    Citation: Mobile DNA 2014 5:30

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  12. Content type: Methodology

    LINE-1 (L1) retrotransposons are common occupants of mammalian genomes representing about a fifth of the genetic content. Ongoing L1 retrotransposition in the germ line and somatic tissues has contributed to s...

    Authors: Mark Sokolowski, Cecily B DeFreece, Geraldine Servant, Kristine J Kines, Dawn L deHaro and Victoria P Belancio

    Citation: Mobile DNA 2014 5:29

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  13. Content type: Review

    Transposable elements (TEs) are major components of genomes. Their mobilization may affect genomic expression and be a threat to genetic stability. This is why they have to be tightly regulated by a dedicated ...

    Authors: Emmanuelle Théron, Cynthia Dennis, Emilie Brasset and Chantal Vaury

    Citation: Mobile DNA 2014 5:28

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  14. Content type: Research

    Hfq functions in post-transcriptional gene regulation in a wide range of bacteria, usually by promoting base pairing of mRNAs with trans-encoded sRNAs. It was previously shown that Hfq down-regulates Tn10 transpo...

    Authors: Joseph A Ross, Ryan S Trussler, Morgan D Black, Crystal R McLellan and David B Haniford

    Citation: Mobile DNA 2014 5:27

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  15. Content type: Meeting Report

    The Mobile Genetic Elements and Genome Evolution conference was hosted by Keystone Symposia in Santa Fe, NM USA, 9 March through 14 March 2014. The goal of this conference was to bring together scientists from...

    Authors: Parmit Kumar Singh, Guillaume Bourque, Nancy L Craig, Josh T Dubnau, Cédric Feschotte, Diane A Flasch, Kevin L Gunderson, Harmit Singh Malik, John V Moran, Joseph E Peters, R Keith Slotkin and Henry L Levin

    Citation: Mobile DNA 2014 5:26

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  16. Content type: Research

    Twin-ribozyme introns represent a complex class of mobile group I introns that harbour a lariat capping (LC) ribozyme and a homing endonuclease gene embedded in a conventional self-splicing group I ribozyme (G...

    Authors: Yunjia Tang, Henrik Nielsen, Benoît Masquida, Paul P Gardner and Steinar D Johansen

    Citation: Mobile DNA 2014 5:25

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  17. Content type: Research

    CACTA elements are DNA transposons and are found in numerous organisms. Despite their low activity, several thousand copies can be identified in many genomes. CACTA elements transpose using a ‘cut-and-paste’ mech...

    Authors: Jan P Buchmann, Ari Löytynoja, Thomas Wicker and Alan H Schulman

    Citation: Mobile DNA 2014 5:24

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  18. Content type: Review

    Transposable elements (TEs) are major structural components of eukaryotic genomes; however, mobilization of TEs generally has negative effects on the host genome. To counteract this threat, host cells have evo...

    Authors: Soichiro Yamanaka, Mikiko C Siomi and Haruhiko Siomi

    Citation: Mobile DNA 2014 5:22

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  19. Content type: Research

    Bari-like transposons belong to the Tc1-mariner superfamily, and they have been identified in several genomes of the Drosophila genus. This transposon’s family has been used as paradigm to investigate the complex...

    Authors: Antonio Palazzo, Roberta Moschetti, Ruggiero Caizzi and René Massimiliano Marsano

    Citation: Mobile DNA 2014 5:21

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  20. Content type: Commentary

    Processed pseudogenes are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome using the enzymatic activities of active L1 elements. Processed pseudogenes generally...

    Authors: Haig H Kazazian Jr

    Citation: Mobile DNA 2014 5:20

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  21. Content type: Opinion

    During the Mobile Genetic Elements and Genome Evolution Keystone Symposium in March 2014, the Editors of Mobile DNA caught up with a panel of conference speakers to select key advances in the field, and hear thei...

    Authors: Marlene Belfort, Luciano Marraffini, Todd Macfarlan, Jef Boeke, Keith Slotkin, Harmit Malik and Lynne Maquat

    Citation: Mobile DNA 2014 5:16

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  22. Content type: Research

    The Drosophila INterspersed Elements-1 (DINE-1/INE1) transposable elements (TEs) are the most abundant component of the Drosophila melanogaster genome and have been associated with functional gene duplications. D...

    Authors: Jainy Thomas, Komal Vadnagara and Ellen J Pritham

    Citation: Mobile DNA 2014 5:18

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  23. Content type: Research

    The Tc1/mariner superfamily of transposable elements (TEs) is widespread in animal genomes. Mariner-like elements, which bear a DDD triad catalytic motif, have been identified in a wide range of flowering plant s...

    Authors: Yuan Liu and Guojun Yang

    Citation: Mobile DNA 2014 5:17

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  24. Content type: Research

    Mammalian-wide interspersed repeats (MIRs) are the most ancient family of transposable elements (TEs) in the human genome. The deep conservation of MIRs initially suggested the possibility that they had been e...

    Authors: Daudi Jjingo, Andrew B Conley, Jianrong Wang, Leonardo Mariño-Ramírez, Victoria V Lunyak and I King Jordan

    Citation: Mobile DNA 2014 5:14

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  25. Content type: Research

    Trichomonas vaginalis is the most prevalent non-viral sexually transmitted parasite. Although the protist is presumed to reproduce asexually, 60% of its haploid genome contains transposable elements (TEs), known ...

    Authors: Martina Bradic, Sally D Warring, Vivien Low and Jane M Carlton

    Citation: Mobile DNA 2014 5:12

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  26. Content type: Commentary

    LINE-1s (L1s), the only currently active autonomous mobile DNA in humans, occupy at least 17% of human DNA. Throughout evolution, the L1 has also been responsible for genomic insertion of thousands of processe...

    Authors: John L Goodier

    Citation: Mobile DNA 2014 5:11

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  27. Content type: Research

    Tos17 was the first LTR retrotransposon (Copia) described as active in cultivated rice, and is present in two copies in the genome of the sequenced Nipponbare variety. Only the chromosome 7 copy is active and abl...

    Authors: Francois Sabot

    Citation: Mobile DNA 2014 5:10

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  28. Content type: Review

    Group I introns are intervening sequences that have invaded tRNA, rRNA and protein coding genes in bacteria and their phages. The ability of group I introns to self-splice from their host transcripts, by actin...

    Authors: Georg Hausner, Mohamed Hafez and David R Edgell

    Citation: Mobile DNA 2014 5:8

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  29. Content type: Reviewer Acknowledgement

    The Editors of Mobile DNA would like to thank all our reviewers who have contributed to the journal in volume 4 (2013).

    Authors: Nancy L Craig, Thomas H Eickbush, Cédric Feschotte and Henry L Levin

    Citation: Mobile DNA 2014 5:3

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  30. Content type: Research

    Hybrid dysgenic syndromes in Drosophila have been critical for characterizing host mechanisms of transposable element (TE) regulation. This is because a common feature of hybrid dysgenesis is germline TE mobiliza...

    Authors: Justin P Blumenstiel

    Citation: Mobile DNA 2014 5:6

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  31. Content type: Research

    Horizontal transfer of transposable elements (HTT) is increasingly appreciated as an important source of genome and species evolution in eukaryotes. However, our understanding of HTT dynamics is still poor in ...

    Authors: Mathilde Dupeyron, Sébastien Leclercq, Nicolas Cerveau, Didier Bouchon and Clément Gilbert

    Citation: Mobile DNA 2014 5:4

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  32. Content type: Review

    Mobile group II introns are bacterial retrotransposons that combine the activities of an autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert site-specifically into DNA. ...

    Authors: Peter J Enyeart, Georg Mohr, Andrew D Ellington and Alan M Lambowitz

    Citation: Mobile DNA 2014 5:2

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  33. Content type: Research

    Transposable elements (TEs) play a major role in genome evolution. Their capacity to move and/or multiply in the genome of their host may have profound impacts on phenotypes and dramatic consequences on genome...

    Authors: Roland Vergilino, Shannon HC Eagle, Teresa J Crease and France Dufresne

    Citation: Mobile DNA 2014 5:1

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  34. Content type: Software

    Accurate and complete identification of mobile elements is a challenging task in the current era of sequencing, given their large numbers and frequent truncations. Group II intron retroelements, which consist ...

    Authors: Michael Abebe, Manuel A Candales, Adrian Duong, Keyar S Hood, Tony Li, Ryan A E Neufeld, Abat Shakenov, Runda Sun, Li Wu, Ashley M Jarding, Cameron Semper and Steven Zimmerly

    Citation: Mobile DNA 2013 4:28

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  35. Content type: Research

    Research into great ape genomes has revealed widely divergent activity levels over time for Alu elements. However, the diversity of this mobile element family in the genome of the western lowland gorilla has prev...

    Authors: Adam T McLain, Glenn W Carman, Mitchell L Fullerton, Thomas O Beckstrom, William Gensler, Thomas J Meyer, Christopher Faulk and Mark A Batzer

    Citation: Mobile DNA 2013 4:26

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