Fig. 3From: CRISPR-TE: a web-based tool to generate single guide RNAs targeting transposable elementsAnalysis of TE sgRNAs in Human and Mouse. A Displays the top 20 TE subfamilies with the highest coverage using the best three sgRNA combinations in human (left panel) and mouse (right panel). B Box plots showing the coverage achieved by the best three sgRNA combinations in each TE family for human (left panel) and mouse (right panel). C. Examples of sgRNAs designed by CRISPR-TE for targeting LTR5HS (upper left panel), L1PA10 (upper right panel), RLTR6BMm (bottom left panel), and B2Mm2 (bottom right panel) TEs. The bar plots indicate the targeted percentage of copies for the top three TE subfamilies using the best three sgRNA combinations. The pie charts represent the genomic distribution of all targeted sites by the corresponding best three sgRNA combinationsBack to article page