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Fig. 2 | Mobile DNA

Fig. 2

From: Pan cancer characterization of genes whose expression has been associated with LINE-1 antisense promoter activity

Fig. 2

The expression pattern of L1 ASP-associated genes in 23 cancers. Aย The number of coding and non-coding genes in 903 L1ASP related genes. Bย GO and KEGG functional enrichment analysis revealed that these genes were closely associated with tumor growth, cell division, cell cycle, and cellular senescence. Cย The number of up-regulated gene expressions was more than the number of down-regulated genes across 15 cancer types. Dย The expression distribution of L1 ASP genes in each tumor indicated that most of the genes were significantly up regulated in the tumor (Pโ€‰<โ€‰0.01). Eย The visualization of significant dysregulation of L1 ASP-associated genes in KIRC, BRCA, and LUSC. Red dots represent up-regulated genes and blue dots represent down-regulated genes

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