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Fig. 5 | Mobile DNA

Fig. 5

From: Reproducible evaluation of transposable element detectors with McClintock 2 guides accurate inference of Ty insertion patterns in yeast

Fig. 5

copia-superfamily retrotransposons show a dyad pattern of insertion in nucleosome-bound regions upstream of yeast tRNA genes. The top four rows show density profiles of non-redundant insertion sites for non-reference Ty predictions made by best-in-class McClintock 2 components (RelocaTE2, TEMP, TEMP2 and TEBreak) in tRNA promoter regions in a panel of 1,011 S. cerevisiae WGS samples [64, 66], down-sampled to 50\(\times\) fold-coverage. Only the four Ty familes (Ty1, Ty2, Ty3 and Ty4) that are know to non-randomly target tRNA genes are included in this analysis. The bottom row shows nucleosome occupancy inferred using MNase-seq data from [69]. Light blue shaded areas indicate 100-bp regions surrounding peaks of nucleosome occupancy

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ISSN: 1759-8753