Fig. 1From: THE1B may have no role in human pregnancy due to ZNF430-mediated silencingA Phylogeny of primates and the timing for the emergence of THE1 retrovirus; BÂ ZNF genes cluster found in human 19p12 locus (only genes with human orthologs from ZNF430 to ZNF43 are shown); CÂ Phylogeny of paralogs of ZNF430 according to Treefam (left panel); Contact residues by each finger and the predicted binding motifs by B1H methods, shown from N- to C- end (right panel); D Distribution of top 500 ChIP-exo peaks for each ZNF enriched in THE1 or other repeat elements (ZNF431 has fewer than 500 peaks in originally reported paper); EÂ Consensus sequence for identified ZNF binding sites in each RVL-MalR retrotransposon; (Data source: Dfam); FÂ Proposed evolutionary history for ZNF430 and its paralogs. G Aggregate H3K9me3 signals around the putative ZNF430 sites within THE1B elements, sorted by mismatches to consensus, (Data source: ENCODE)Back to article page