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Fig. 1 | Mobile DNA

Fig. 1

From: T3E: a tool for characterising the epigenetic profile of transposable elements using ChIP-seq data

Fig. 1

Young TE families/subfamilies are mainly covered by multimappers. A Fraction of reads mapping to TEs and regions not annotated as TEs (non-TE) in the human genome, separated into uni- and multimappers, for 37 ChIP-seq libraries (red) and their input controls (blue) (Datasets 1–3; Methods). File accession names are indicated on the x-axis. Individual copies belonging to the same TE family/subfamily are usually not identical. B Percentage covered by TE classes and non TEs in the human genome. TEs with unknown classification are reported as “Unknown”. The fraction of the human genome not covered by TEs is indicated by “non-TE”. Nearly half of the human genome comprises TEs. C Fraction of uni- (green) and multimappers (grey) mapping to TEs present in different eukaryotic clades. A TE family/subfamily was associated with unimappers (multimappers) if at least 90% of the reads mapping to its copies were unimappers (multimappers) in all ChIP-seq samples and input controls of Dataset 1. The vast majority of unimappers map to TEs that expanded in the common ancestor of amniotes (~ 310 million years ago); in contrast, most multimappers are associated with TEs that expanded in the earliest primates (~ 85 million years ago) and their descendants

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