Fig. 9From: Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal intronsPotential model for antisense HEG expression in Didymium cells. Extrachromosomal rDNA copies are located both in nucleolus and nucleoplasm. The nucleolar rDNA (left) generates an RNA pol I transcript covering the SSU and LSU rRNA genes, and group I intron Dsq.L2066. Intron RNA self-splicing and processing results in ligated exons, excised intron, and full-length intron circles. The nucleoplasm rDNA (right) generates an RNA pol II transcript covering the HEG. Maturation of the corresponding I-DsqI mRNA involves removal of spliceosomal intron (I-47) and polyadenylation. These two processes are separated in space and probably time, avoiding antisense interference between pre-rRNA transcripts and mRNABack to article page