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Fig. 9 | Mobile DNA

Fig. 9

From: Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns

Fig. 9

Potential model for antisense HEG expression in Didymium cells. Extrachromosomal rDNA copies are located both in nucleolus and nucleoplasm. The nucleolar rDNA (left) generates an RNA pol I transcript covering the SSU and LSU rRNA genes, and group I intron Dsq.L2066. Intron RNA self-splicing and processing results in ligated exons, excised intron, and full-length intron circles. The nucleoplasm rDNA (right) generates an RNA pol II transcript covering the HEG. Maturation of the corresponding I-DsqI mRNA involves removal of spliceosomal intron (I-47) and polyadenylation. These two processes are separated in space and probably time, avoiding antisense interference between pre-rRNA transcripts and mRNA

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