Fig. 2From: SETMAR, a case of primate co-opted genes: towards new perspectivesOverview of SETMAR activities, involved in replication fork restart after repair, NHEJ DNA repair, chromosomes decatenation and various epigenetics mechanisms. Usual cancer treatments are shown in red (IR: radiation, VP-16 and HU: chemicals). Cellular pathways activated or supported by SETMAR are represented in green. Identified post-translational modifications (PTM) and SETMAR partners are indicated. The picture only concerns FL-SETMAR activities because S-SETMAR activities are not well documented. So far, we know that S-SETMAR disturbs the NHEJ activity of FL-SETMAR, and does not display methyl-transferase activityBack to article page