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Fig. 1 | Mobile DNA

Fig. 1

From: Chromosomal integration of Tn5253 occurs downstream of a conserved 11-bp sequence of the rbgA gene in Streptococcus pneumoniae and in all the other known hosts of this integrative conjugative element (ICE)

Fig. 1

Allelic variants of the Tn5253 attB integration site in S. pneumoniae. Tn5253 attB is located in the essential pneumococcal rbgA gene. In the 85 complete S. pneumoniae genomes, 13 allelic variants of attB were found. The 83-bp variant 1 (attB1) is the most frequent, carried by 38 genome strains (44.7 % of the analyzed genomes), including D39 strain, its rough derivative R6, and A66 strain, and was used as reference for the alignment. Variant 2 is carried by TIGR4 and other 8 genome strain and contains 2 nucleotide substitutions. BM6001, the original Tn5253-carrying clinical strain, and DP1322, in which Tn5253 was transferred by transformation from BM6001, harbour variant 5. SP18-BS74, whose draft genome is available, harbours the 41-bp variant 13. Within the sequences, identical nucleotides are indicated by periods, substitutions in red. For better alignment, dashes are inserted. The 20 nucleotides belonging to the rbgA coding sequence are underlined

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Mobile DNA

ISSN: 1759-8753