Table 3 Genomic distribution and gene ontology enrichment of genes significantly associated with TEs in the AT2 and AM cells. A gene ontology (GO) enrichment analysis was performed on those genes with significant cis TE associations using the STRING database [40]. The total number of observed and background genes in each GO term category as well as all false discovery rate values (FDR) < 0.05 are shown for the AT2 and AM cells
GO TERM | Description | Observed gene count | Background gene count | FDR |
|---|---|---|---|---|
AT2 | ||||
 GO:0035082 | axoneme assembly | 6 | 59 | 0.002 |
 GO:0003341 | cilium movement | 5 | 61 | 0.009 |
 GO:0060271 | cilium assembly | 10 | 326 | 0.009 |
 GO:0070286 | axonemal dynein complex assembly | 4 | 32 | 0.009 |
 GO:0120031 | plasma membrane bounded cell projection assembly | 11 | 413 | 0.009 |
 GO:0036159 | inner dynein arm assembly | 3 | 16 | 0.026 |
 GO:0070925 | organelle assembly | 12 | 666 | 0.044 |
AM | ||||
 GO:0006955 | immune response | 16 | 1560 | 0.016 |
 GO:0045124 | regulation of bone resorption | 4 | 38 | 0.016 |
 GO:0002376 | immune system process | 19 | 2370 | 0.028 |