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Fig. 4 | Mobile DNA

Fig. 4

From: The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis

Fig. 4

Summary of the IPF-associated TE loci changes and their association with the adjacent genes. a A Venn diagram of the overlap between the upregulated TE loci in the IPF patients when compared with the donors in whole-lung tissue (WT), alveolar type II cells (AT2), and alveolar macrophages (AM) (upper number). An overlap between the upregulated (first number in the brackets) and downregulated genes (second number in the brackets) is also shown. b Histograms summarizing the TE expression changes by intergenic and intragenic regions in the WL, AT2 and AM. The intragenic regions are divided into the 3’UTR, 5’UTR, intron, and exon regions. The different colors represent the proportion of each TE family in each region. The x-axis represents the individual genomic region. The y-axis represents the percentage of TE loci per TE family that are normalized by the total number of each TE family present in each genomic region

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ISSN: 1759-8753