Fig. 3From: Methylation of rRNA as a host defense against rampant group II intron retrotranspositionFunctional category comparison of RTP-up mutants. Comparison of the COG distribution of RTP-up mutants against the mutant library. An asterisk represents a statistically significant difference (p < 0.05) using a hypergeometric test, whereas triangles point to categories that are enriched in RTP-up mutants, but not statistically different. A significant difference is observed in COG category E, which corresponds to amino acid transport and metabolism. Enrichment of RTP-ups is also observed in several categories: J, translation, ribosomal structure and biogenesis; K, transcription; T, signal transduction; P, inorganic ion transport and metabolism; and X, mobile genetic elements. A key of all COG categories is in Additional File 1: Table S3Back to article page