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Fig. 1 | Mobile DNA

Fig. 1

From: Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates

Fig. 1

Structural features of Platyrrhini ERV-W proviruses. In panel A, presence and nucleotide positions of selected ERV-W structural elements are depicted for proviral consensus sequences generated from marmoset (CalJac) and squirrel monkey (SaiBol) ERV-W datasets. Nucleotide differences between both consensuses are indicated as vertical lines between the two provirus maps. Coordinates of a putative ORF identified within the pre-gag region are also annotated. The reading frame for translation of Gag, Pro and Pol proteins is indicated by a dotted arrow. Typical for retroviruses, Env is very likely translated from a spliced env mRNA. Panel B depicts selected sequence features in marmoset and squirrel monkey ERV-W sequences: a PBS predicted to be specific for tRNAArg (found in 81% and 84,5% of ERV-W elements, respectively); Gag nucleocapsid zinc fingers I (found in 63 and 33% of ERV-W elements, respectively) and II (found in 51 and 52% of ERV-W elements, respectively); and Pol integrase GPY/F (found in 42 and 35%, respectively). Respective motifs were counted as present only in the absence of internal stop codons and amino acid substitutions at the specific residues

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