TY - JOUR AU - Ueda, Mahoko Takahashi AU - Kryukov, Kirill AU - Mitsuhashi, Satomi AU - Mitsuhashi, Hiroaki AU - Imanishi, Tadashi AU - Nakagawa, So PY - 2020 DA - 2020/09/17 TI - Comprehensive genomic analysis reveals dynamic evolution of endogenous retroviruses that code for retroviral-like protein domains JO - Mobile DNA SP - 29 VL - 11 IS - 1 AB - Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of mammalian germline cells. A large proportion of ERVs lose their open reading frames (ORFs), while others retain them and become exapted by the host species. However, it remains unclear what proportion of ERVs possess ORFs (ERV-ORFs), become transcribed, and serve as candidates for co-opted genes. SN - 1759-8753 UR - https://doi.org/10.1186/s13100-020-00224-w DO - 10.1186/s13100-020-00224-w ID - Ueda2020 ER -