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Fig. 1 | Mobile DNA

Fig. 1

From: Finding and extending ancient simple sequence repeat-derived regions in the human genome

Fig. 1

Clustering of SSR loci depending on motif similarity. All perfect SSRs (≥12 bp) were annotated in a transposable-element masked version of the human genome (hg38) and the count of nearby SSR motifs were recorded as a function of distance from the repeat. Here, we show the 5 motifs that are most frequently found near (a) perfect poly-A SSRs (n = 350,763); and (b) perfect (AC)n SSRs (n = 85,161). The motifs of nearby SSRs often differ from the repeated motif by simple mutations. To allow for overlapping non-reference motif families (i.e., a compound locus comprised of two or more different motif families), x = 0 begins 11 bp within the perfect reference motif repeat. Flat curves at x = 0 reflects that the first several bases are still part of the perfect repeat and thus can only be annotated by another family to the extent that their motifs overlap

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