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Fig. 2 | Mobile DNA

Fig. 2

From: Convergence in LINE-1 nucleotide variations can benefit redundantly forming triplexes with lncRNA in mammalian X-chromosome inactivation

Fig. 2

Redundant-UC/redundant-AG (r-UC/r-AG) motifs in Xist/XIST/Rsx RNAs and human long noncoding RNAs (lncRNAs), and motif–length distributions. a Distributions of r-UC/r-AG motifs dispersed in Xist/XIST/Rsx RNAs, with alignments of Xist/XIST RNA tandem repeats (A–E repeats). Vertical light blue and red bars represent the sites of r-UC and r-AG motifs, respectively. The total numbers and proportions of the motifs in the lncRNAs are indicated. Bold square brackets are under the regions of singly clustered r-UC or r-AG motifs. b r-UC/r-AG motifs in lncRNAs longer than 5,000 nucleotides with known functions. The left Y-axis shows the percentage of redundant-UC (r-UC) (light blue) and redundant-AG (r-AG) (red) motifs in 46 human lncRNAs and Xist/XIST/Rsx RNAs (listed below the X-axis with their length (in nucleotides)). The right Y-axis shows the r-UC/r-AG motif ratio (black line with dots) occupied in lncRNAs. c r-UC/r-AG motif–length distribution in Xist/XIST/Rsx RNA. The total number and the maximum length (Max.) of the motifs are indicated. Kolmogorov–Smirnov (KS) distance values are indicated at the bottom. nt, nucleotides

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ISSN: 1759-8753