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Fig. 1 | Mobile DNA

Fig. 1

From: The impact of transposable element activity on therapeutically relevant human stem cells

Fig. 1

Human stem cell-based clinical studies conducted worldwide (Status: October 2018; a Interventional clinical trials (Phase I or phase I/II) applying adult stem cell types (mesenchymal stem cells, MSCs; hematopoietic stem cells, HSCs; neuronal stem cells, NSCs) or their differentiated derivatives, or embryonic stem cell (ESC)-or induced pluripotent stem cell (iPSC)-derived differentiated cells. Numbers in brackets indicate the number of individual trials based on the respective stem cell type. b Interventional clinical trials and observational studies that are currently ongoing or in preparation use therapeutic derivatives of ESCs (blue lettering) or iPSCs (green lettering) to treat ophthalmic, urological, blood, cardiac and genital diseases, neurological disorders and cancers/neoplasms. Numbers in brackets represent the number of clinical trials and/or observational studies initiated to treat the respective disease or disorder

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