An advanced enrichment method for rare somatic retroelement insertions sequencing

Table 2 Number of sequencing reads and UMIs corresponding to putative somatic insertions and spike-in controls

Putative somatic Alu insertions	Unnormalized	Normalization 1	Normalization 2
Sequencing reads	56(47)^a	609(218)^a	1,525(461)^a
Total number	47	171	378
Number with UMI count > 1	0	24	38
Spike-in controls
DR240 (in 5 cells^b)	0	4(3)^a	7(4)^a
DR389 (in 5 cells^b)	1(1)^a	1(1)^a	1(1)^a
DR259 (in 1 cell^c)	0	0	1(1)^a
DR418 (in 1 cell^c)	0	0	0

ISSN: 1759-8753