Fig. 2

Phylogeny of SVA_D elements in hominines. Median-joining networks of the SVA_D SINE-R domains. Networks were rooted on SVA_C and are not drawn to scale. Elements shared between the lineages are shown as fraction of the total number of members of a subfamily. A color code for shared elements is provided at the left. Ovals indicate the major expanding subfamilies in the different lineages: SVA_D elements with characteristic 228 A – 242 G substitutions in gorilla and chimpanzee and SVA_F in humans. The part of the human network displaying the 228 A – 242 G substitutions is marked as well. SVA_E is included in the human network to comprehensively reflect the spectrum of currently active SVA elements. gg – gorilla; pt – chimpanzee; hs – human