Fig. 2

GO analyses of genes containing AMH-specific RIs. a Heat maps representing -log (p-values) of GO terms associated with genes that contain AMH-specific RIs vs chimp (top) and AMH-specific RIs vs both HN/HD (bottom), ordered for increased significance in the top row. b Scatterplot representation of the identified Hominina-specific GO terms. The x and y coordinates of the circles were derived from the Revigo analysis, based on multidimensional scaling on the matrix with the GO semantic similarity values. The functional categories associated with genes that form networks are highlighted and labeled. c Scatterplot representation of the identified sapiens-specific GO terms. The x and y coordinates of the circles were derived from the Revigo analysis, based on multidimensional scaling on the matrix with the GO semantic similarity values. The functional categories associated with genes that form networks are highlighted and labeled. d Functionalities of sapiens-specific GO terms associated in networks (if applicable). Red terms are neural-related while blue terms are not. e Gene network of genes containing AMH-specific RIs absent in both HN and HD with neural functionalities. The larger the circle, the more the gene represented by it has interactions with other genes in the network. The sub-network showing strong interactions with the gene SHTN1 is highlighted in the top-right, while the sub-network with more interactions with the gene EDEM3 is highlighted in the bottom-right