Fig. 7

Germline de novo expansion of the Merle oligo(dT) tract. Photographs and fragment analysis chromatograms are shown for a standard merle sire (a) and his harlequin merle daughter (b), as well as a standard merle dam (c) and her harlequin merle daughter (d). Amplicon size in base pairs is shown on the x-axis, and the y-axis measures signal intensity (RFU). Genotypes are given above the chromatogram for each dog with M denoting the inherited Merle allele, m representing the wild-type allele (not pictured), and (M) signifying somatic contractions of the longer de novo Merle allele