From: Retrotransposon targeting to RNA polymerase III-transcribed genes
Mobile element | Clade | Hosta | Preferred integration site | Host factors mediating this insertion preference |
---|---|---|---|---|
LTR Retrotransposons | ||||
Ty1 | Ty1-copia | Saccharomyces cerevisiae | ~ 1 kb window upstream of RNA Pol III-transcribed genes, including tRNA and 5S rRNA genes [13, 14, 21] | Ty1-IN interaction with Rpc40 [29] and Ty1-IN interaction with Rpc53, Rpc34, Rpc31 [30] |
Ty2 | Ty1-copia | Saccharomyces cerevisiae | ~ 1 kb window upstream of RNA Pol III-transcribed genes [21] |  |
Ty3 | Ty3-gypsy | Saccharomyces cerevisiae | 1–4 bp upstream of tRNA TSSb [93] | |
Ty3p | Ty3-gypsy | Saccharomyces paradoxus | ~ 6 bp upstream of tRNA TSS [110] |  |
Ty4 | Ty1-copia | Saccharomyces cerevisiae | ~ 1 kb window upstream of RNA Pol III-transcribed genes [21] |  |
Tj1 | Ty3-gypsy | Schizosaccharomyces japonicus | 1–10 bp upstream of tRNA TSS [121] |  |
Beta/Tca8 | Ty3-gypsy | Candida albicans | 6-30Â bp upstream of tRNA MCSc [119] | Â |
Tyl3 | Ty3-gypsy | Yarrowia lipolytica | ~ 5 bp upstream of tRNA TSS [116] |  |
Ylt1 | Ty3-gypsy | Yarrowia lipolytica | ~ 5 bp upstream of tRNA TSS [117] |  |
Tyl6 | Ty3-gypsy | Yarrowia lipolytica | ~ 5 bp upstream of tRNA TSS [115] |  |
DGLT-A | Ty3-gypsy | Dictyostelium discoideum | 13–33 bp upstream of tRNA MCS [125] |  |
Skipper-2 | Ty3-gypsy | Dictyostelium discoideum | Â | |
Non-LTR Retrotransposons | ||||
TRE5 | L1 | Dictyostelium discoideum | 40–54 bp upstream of tRNA MCS; 37–41 bp upstream of extrachromosomal 5S rRNA genes [125, 134, 135, 174] | TRE5 ORF1 interaction with TFIIIB [132] |
TRE3 | L1 | Dictyostelium discoideum | Â | |
NLTR-A | L1 | Dictyostelium purpureum | 2–6 bp upstream of tRNA MCS [124] |  |
NLTR-B | L1 | Polysphondylium pallidum | 39–64 bp upstream of tRNA MCS [124] |  |