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Table 5 Phylogeographic distribution of distinct alleles of the hypervariable subset of tfs3 left flank genes

From: Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements

  

Prevalence (%) of distinct alleles (1–5) of the four most variable tfs3 left flank genes in H. pylori populations

  

t3_V24. (pz36)

t3_C3. (pz35)

t3_C2. (pz34)

t3_V25. (pz30)

Population

Strains (tfs3+)1

1

2

3

4

1

2

3

4

5

1

2

3

4

1

2

3

hpEurope

34

25 (74)

1a (3)

5 (15)

–

271 (79)

1a (3)

–

4 (12)

–

25 (74)

–

–

4 (12)

21 62)

1 (3)

4 (12)

hpAfrica1

53

45d (85)

–

2b (4)

4 (8)

45d (85)

–

–

2 (4)

5 (9)

42d (79)

–

5 (9)

2 (4)

43c (81)

–

4 (8)

hpAfrica2

0

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

–

hpAsia2

5

–

3a (60)

2 (40)

–

–

2 (40)

2b (40)

–

–

1 (20)

3a (60)

–

1 (20)

4 (80)

1 (20)

–

hspEAsia

14

–

12d (86)

3 (21)

–

–

12d (86)

2 (14)

–

–

–

11d (79)

–

4a (29)

2a (14)

11d (79)

–

hspAmerind

5

1 (20)

–

2c (40)

2a (40)

1a (20)

–

–

2a (40)

2a (40)

–

–

2a (40)

2 (40)

–

–

5d (100)

Totals

111

71 (64)

16 (14)

14 (13)

6 (5)

73 (66)

15 (14)

4 (4)

8 (7)

7 (6)

68 (61)

14 (13)

7 (6)

13 (12)

70 (63)

13 (12)

13 (12)

  1. 1tfs3+ defined as ≥2 genes in the tfs3 left flank. P value was determined by Fisher’s Exact Test and indicates significant association (positive or negative) of the indicated tfs3 allele with a particular MLST. aP < 0.05, bP < 0.01, cP < 0.001, dP < 0.000, 1P = 0.052