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Fig. 3 | Mobile DNA

Fig. 3

From: Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain

Fig. 3

Immunoperoxidase detection of endogenous L1-ORF1p in different regions of sections of the normal human brain. Human α-L1 ORF1p (RRM) was used to detect the expression L1 activity in human three different brain tissues: hippocampus, basal ganglia and frontal cortex. Samples from three different aged brains (80 year, 55 year and 15 year old) were analyzed. Images were taken at 40X magnifications. Panel 4, leftmost: Immunoperoxidase staining of frontal cortex from 77 year old individual. Panel 4 middle: As a negative control, the immunostaining procedure was performed without primary antibody on a hippocampus section from a 55-year old individual. Panel 4 rightmost: In another negative control, IHC was performed on the same section using primary α-hORF1p (RRM) (raised in rabbit) followed by secondary α-mouse

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