Fig. 5

Phylogenetic relationships and domain architecture of FOSC and other fungal Helitrons, Helentrons and canonical Helitrons. Phylogeny based on a multiple sequence alignment of known Helitrons and Helentrons from RepBase, and a set of fungal Helitrons detected by scanning fungal proteomes for proteins with a Hel-Rep domain architecture. Due to space constraints, we do not show all proteins included in the phylogeny but selected a subset that represents the full tree as depicted in Additional file 1: Figure S13. We inferred a 100 bootstrap replicates: thick branches have a bootstrap value of 100 and grey branches a bootstrap value < 70. Branches with bootstrap values < 50 have been removed. Background color of leaves indicates taxonomy: yellow - Fungi, light-blue insects, blue – other Animals, green - Plants, dark green - Red Algae, purple – Oomycetes. All proteins included in this tree have a Hel and a Rep domain. The Helentrons that posses an endonuclease domain, often combined with a OTU domain, form a distinct group