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Table 2 Detection of HML-10(DAP3) pol transcripts by previously reported microarray studies [79]

From: The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation

Tissue/cell type HML-10(DAP3) RNA expressed HML-10(DAP3) RNA not expressed HML-10(DAP3) RNA variably expressed
Normal tissue and non-tumor cell lines (n = 23) Cervix [22], epidermal keratinocytes (HaCaT) [26], thyroid [22], umbilical vein endothelial cells (HUVEC) [40], uterus [22] (5/23) Blood [22, 23], breast [25], colon [22], heart [22], liver [22], lung [22], mamma [22, 23], neural stem cells (HNSC.100) [40], ovary [22], placenta [22], prostate [22], rectum [22], skeletal muscle [22], stomach [22], testes [22] (15/23) Brain [22, 24], kidney [22, 27], skin [22, 41] (3/23)
Primary tumors and tumor cell lines (n = 13) CAKI (renal carcinoma) [26], GliNS1 (neural tumor stem line) [40], HEK293 (embryonic kidney) [26], HeLa (cervix adenocarcinoma) [26], HuH-7 (hepatocellular carcinoma) [26], MIA PaCa-2 (pancreatic carcinoma) [26], SK-N-MC (neuroblastoma) [42, 43], SK-N-SH (neuroblastoma) [42], T47D (ductal breast epithelial carcinoma) [26], U-251MG (glioblastoma) [42] (10/13) Breast cancer [25], U-138MG (glioblastoma) [42] (2/13) Renal cell carcinoma [27] (1/13)
  1. Numbers in parentheses indicate how many of the analyzed tissue/cell types show the respective expression status of HML-10(DAP3) RNA