Fig. 7

Genome ARTIST and iMapper proficiencies in analysing batches of 102 virtual query sequences containing mutations. The figure summarizes the mapping performances of Genome ARTIST (in red) and iMapper (in blue) when small-scale mutations are simulated in a set of 102 query sequences standing for computed insertions of P{lacW} adjacent to 102 randomly selected genes from D. melanogaster. Genome ARTIST correctly maps 72/102 insertions (y-axis) when one-nucleotide deletion in the critical position 2 relative to TGN is simulated (x-axis) (Fig. 6a) and 79/102 insertions if a SNP is placed in the same position (Fig. 6b), while iMapper is unable to accurately map any of the respective simulated insertions. For the majority of the other simulations, Genome ARTIST is also superior to performances of iMapper. We noticed an exception when the SNP is placed in position 4 relative to TGN, for which Genome ARTIST correctly maps 99 virtual insertions, while iMapper successfully maps all of them