|
Gene
|
Functiona
|
Ty1 moblility relative to WT
|
Frameshifting relative to WT
|
Polysome effects
|
Gag relative to WT
|
Ty1 mRNA relative to WT
|
|---|
|
RPL1B
|
LSU protein
|
0.12
|
0.23
|
↓60S/halfmers
|
0.001
|
2.0
|
|
RPL4A
|
“
|
0.48
|
0.70
|
↓60S/halfmersb
|
0.60
|
1.6
|
|
RPL15B
|
“
|
0.07
|
1.0
|
~WT
|
0.80
|
n.d.
|
|
RPL21A
|
“
|
0.12
|
0.67
|
n.d.
|
0.46
|
1.9
|
|
RPL27A
|
“
|
0.16
|
0.39
|
↓60S/halfmers
|
0.70
|
2.0
|
|
RPL39
|
“
|
0.005
|
0.44
|
↓60Sc
|
0.002
|
0.75
|
|
RPL41B
|
“
|
0.20
|
1.1
|
~WT
|
0.86
|
1.4
|
|
RPP2B
|
“
|
0.08
|
0.50
|
WTd
|
0.65
|
2.0
|
|
RPS0B
|
SSU protein
|
0.14
|
0.40
|
↓40S
|
0.30
|
0.71
|
|
RPS9B
|
“
|
0.12
|
0.57
|
n.d.
|
0.37
|
1.2
|
|
RPS10A
|
“
|
0.12
|
0.43
|
↓40S
|
0.20
|
1.0
|
|
RPS19B
|
“
|
0.04
|
0.50
|
↓40S
|
0.35
|
0.12
|
|
RPS25A
|
“
|
0.20
|
1.0
|
~WTe
|
0.14
|
n.d.
|
|
RRP6
|
LSU processing
|
0.07
|
0.69
|
↓60S/halfmers
|
0.45
|
n.d.
|
|
RRP8
|
SSU processing
|
0.10
|
0.50
|
↓40S
|
0.76
|
0.88
|
|
KAP123
|
60S nuclear export
|
<0.01
|
0.99
|
~WT
|
0.44
|
1.8
|
-
aLSU = large (60S) ribosomal subunit; SSU = small (40S) ribosomal subunit
-
bOhtake et al. [72] cSachs & Davis [73] dCardenas et al. [53] eLéger-Silvestre et al. [74]
