Figure 1
From: Mechanism of spacer integration links the CRISPR/Cas system to transposition as a form of mobile DNA
Overview and details of a CRISPR locus. (A) Clustered regularly interspaced short palindromic repeats (CRISPRs, in green) typically alternate with spacers of different sequence but similar length (shades of gray and black). (B) Proposed double-ended integration of a protospacer (red) into the site of a CRISPR repeat. This results in a duplication of the CRISPR. (C) Sequence and deduced cruciform structure of the E. coli 28Â nt CRISPR repeat.