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Figure 5 | Mobile DNA

Figure 5

From: Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition

Figure 5

Models for H-NS binding to the Tn5 transpososome. (A) and (B) Models wherein a head-to-head dimer of H-NS is docked to either the 'front' or 'back' face of the transpososome. Helices 1 to 4 of H-NS are labeled, as are specific basepairs in the transposon ends that were mutated in this study (red). Individual monomers of H-NS are in different colors (cyan and magenta) and the residues linking H4 and the DNA-binding domain of H-NS are in black. Tn5 transposase residues are in grey and end sequence is in gold, blue or red. DBL; DNA-binding loop.

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