Characterization and potential functional significance of human-chimpanzee large INDEL variation

Table 10 Proportions of differentially expressed or non-differentially expressed genes associated with INDELs are significantly different

Tissue type	DE genes with NIS-associated INDELs/total DE genes (%)	Non-DE genes with NIS-associated INDELs/total non-DE genes (%)	Proportions test (P-value)
Brain	801/2,266 + 4,618 (12%)	762/2,153 + 5,096 (1%)	0.036
Testis	1,193/3,438 + 7,365 (11%)	440/1,256 + 3,386 (0.94%)	0.0041
Heart	777/2,233 + 4,610 (11%)	658/1,948 + 4,706 (0.98%)	0.006
Liver	590/1,696 + 3,612 (11%)	838/2,466 + 5,910 (1%)	0.041
Kidney	732/2,179 + 4,410 (11%)	768/2,144 + 5,326 (1%)	0.11

DE = differentially expressed; INDEL = insertion and deletion; non-DE = non-differentially expressed; NIS = noninterspersed sequence. Proportions are shown for all NIS-associated INDELs across all tissues.