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Table 6 Short target site duplications (TSDs) with or without allowing nucleotide substitutions

From: Different integration site structures between L1 protein-mediated retrotransposition in cis and retrotransposition in trans

 

L1

Alu

 

Full

Trun

Inv

Full

Trun

5-bp TSD in relaxed criterion*/

5-bp TSD in strict criterion*

0/3

(0%)

36/56

(64%)

0/4

(0%)

13/51

(25%)

5/18

(28%)

6-bp TSD in relaxed criterion*/

6-bp TSD in strict criterion*

0/4

(0%)

51/64

(80%)

0/6

(0%)

14/69

(20%)

6/26

(23%)

  1. *TSD in relaxed criterion allows 1-bp substitution sandwiched by ≥2-bp homologous nucleotides, but TSD in strict criterion does not.
  2. Full, full-length; Trun, 5'-truncated; Inv, 5'-inverted.
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Mobile DNA

ISSN: 1759-8753