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Figure 3 | Mobile DNA

Figure 3

From: Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells

Figure 3

Absence of eccDNA homologous to the dispersed Alu repeats. HEK-293 (human embryonic kidney cells) DNA, was cleaved with Eco RI followed by 'plasmid safe' digestion and analysed on a two-dimensional gel. Hybridization of the blot with Alu probe revealed only the arc that corresponds to linear DNA (A). Rehybridization of the same blot with Sst I probe revealed both linear DNA and eccDNA multimers (B). Arrowheads indicate the circular multimers.

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