Figure 2
From: Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells
Extrachromosomal circular multimers of the human Sst I satellite DNA. Genomic DNA from HEK-293 (human embryonic kidney cells) (A) and LAN-1 (B) cells was cleaved with Eco RI, digested with 'plasmid safe' DNase, analysed on 2D gels and hybridized with Sst I probe. A ladder of discrete spots indicates open circles in the size of multiples of the 2.5 kb repeating unit. Arrowheads indicate the multimers.