Editors' picks


Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export. [Nucleic Acids Res. 2017 Mar] PubMed

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion. [Nucleic Acids Res. 2017 Mar] PubMed

Inhibition of human endogenous retrovirus-K by antiretroviral drugs. [Retrovirology. 2017 Mar] PubMed

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. [Nature. 2017 Mar] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Proc Natl Acad Sci U S A. 2017 Mar] PubMed 

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. [J Cell Sci. 2017 Mar] PubMed 

Reverse Transcription in the Saccharomyces cerevisiae Long-Terminal Repeat Retrotransposon Ty3. [Viruses. 2017 Mar] PubMed

Convergence of retrotransposons in oomycetes and plants. [Mob DNA. 2017 Mar] PubMed

Non-Homologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe. [Genetics. 2017 Mar] PubMed

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. [PLoS Genet. 2017 Mar] PubMed

Speciation network in Laurasiatheria: retrophylogenomic signals. [Genome Res. 2017 Mar] PubMed

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. [Nat Genet. 2017 Mar] PubMed

A transposon-derived small RNA regulates gene expression in Salmonella Typhimurium. [Nucleic Acids Res. 2017 Feb] PubMed

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification. [Nucleic Acids Res. 2017 Feb] PubMed

A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis. [Sci Rep. 2017 Feb] PubMed

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal. [E Life. 2017 Feb] PubMed

The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia. [Clin Chem. 2017 Feb] PubMed

Transposition of the bamboo Mariner-like element Ppmar1 in yeast. [Mol Phylogenet Evol. 2017 Feb] PubMed

Co-chaperone Hsp70/Hsp90 organizing protein (Hop) is Required for Transposon Silencing and piRNA Biogenesis. [J Biol Chem. 2017 Feb] PubMed

Sequencing the extrachromosomal circular mobilome reveals retrotransposon activity in plants. [PLoS Genet. 2017 Feb 17] PubMed

ALUternative Regulation for Gene Expression. [Trends Cell Biol. 2017 Feb] PubMed

Transposable Element Bm1645 is a Source of BmAGO2-associated Small RNAs that affect its expression in Bombyx mori. [BMC Genomics. 2017 Feb] PubMed

Conserved expression of transposon-derived non-coding transcripts in primate stem cells. [BMC Genomics. 2017 Feb] PubMed

Single genome retrieval of context-dependent variability in mutation rates for human germline. [BMC Genomics. 2017 Jan] PubMed

Hsp90 and physiological stress are linked to autonomous transposon mobility and heritable genetic change in nematodes. [Genome Biol Evol. 2017 Jan] PubMed

An optimized, broadly applicable piggyBac transposon induction system. [Nucleic Acids Res. 2017 Jan] PubMed

Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition. [Genetics. 2017 Jan] PubMed

The FACT complex promotes avian leukosis virus DNA integration. [J Virol. 2017 Jan] PubMed

G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition. [Nat Struct Mol Biol. 2017 Jan] PubMed

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. [Nucleic Acids Res. 2017 Jan] PubMed

Transposase-Mediated Excision, Conjugative Transfer and Diversity of ICE6013 in Staphylococcus aureus. [J Bacteriol. 2017 Jan] PubMed

Protein splicing of a recombinase intein induced by ssDNA and DNA damage. [Genes Dev. 2016 Dec] PubMed

Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila. [Genes Dev. 2016 Dec] PubMed

A supramolecular assembly mediates lentiviral DNA integration. [Science. 2017 Jan] PubMed

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. [Science. 2017 Jan] PubMed

Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis. [Appl Environ Microbiol. 2017 Jan] PubMed

piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice. [Proc Natl Acad Sci U S A. 2017 Jan] PubMed

GB3.0: a platform for plant bio-design that connects functional DNA elements with associated biological data. [Nucleic Acids Res. 2017 Jan] PubMed 

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition. [Genetics. 2017 Jan] PubMed

TET enzymes: double agents in the transposable element-host genome conflict. [Genome Biol. 2016 Dec] PubMed

Endogenous retroviral promoter exaptation in human cancer. [Mob DNA. 2016 Dec] PubMed

Incidental mutations occur frequently during transposon mutagenesis. [FEMS Microbiol Lett. 2016 Dec] PubMed

Paralog-Specific Functions of RPL7A and RPL7B Mediated by Ribosomal Protein or snoRNA Dosage in Saccharomyces cerevisiae. [G3 (Bethesda). 2016 Dec] PubMed

DNA binding specificities of Escherichia coli Cas1-Cas2 integrase drive its recruitment at the CRISPR locus. [Nucleic Acids Res. 2016 Dec] PubMed

Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion. [Nucleic Acids Res. 2016 Dec] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Multiple Transcriptional and Post-Transcriptional Pathways Collaborate To Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast. [Genetics. 2016 Dec] PubMed

Non-canonical Helitrons in Fusarium oxysporum. [Mob DNA. 2016 Dec] PubMed

Destabilization of B2 RNA by EZH2 Activates the Stress Response. [Cell. 2016 Dec] PubMed

The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells. [Genome Res. 2017 Jan] PubMed

Regulated complex assembly safeguards the fidelity of Sleeping Beauty transposition. [Nucleic Acids Res. 2017 Jan] PubMed

L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes. [Nucleic Acids Res. 2017 Jan] PubMed

Telomeric Retrotransposon HeT-A Contains a Bidirectional Promoter that Initiates Divergent Transcription of piRNA Precursors in Drosophila Germline. [J Mol Biol. 2016 Dec] PubMed

Engineered LINE-1 retrotransposition in non-dividing human neurons. [Genome Res. 2016 Dec] PubMed

New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination. [FEBS J. 2016 Dec] PubMed

A map of mobile DNA insertions in the NCI-60 human cancer cell panel. [Mob DNA. 2016 Oct] PubMed

MTV, an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in Drosophila. [PLoS Genet. Nov 2016] PubMed

Retroviruses integrate into a shared, non-palindromic DNA motif. Nat Microbiol. 2016 Nov] PubMed 

Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme. [Mob DNA. 2016 Nov] PubMed

Somatic retrotransposition is infrequent in glioblastomas. [Mob DNA. 2016 Nov] PubMed

Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression. [Proc Natl Acad Sci U S A. 2016 Nov] PubMed

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity. [Science. 2016 Nov] PubMed

Numerous small hammerhead ribozyme variants associated with Penelope-like retrotransposons cleave RNA as dimers. [RNA Biol. 2016 Nov] PubMe

The impact of transposable elements on mammalian development. [Development. 2016 Nov] PubMed

Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder. [Sci Rep. 2016 Nov] PubMed

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences. [Mol Cell. 2016 Dec] PubMed

Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition. [Mob DNA. 2016 Nov] PubMed

Patterns of Transposable Element Expression and Insertion in Cancer. [Front Mol Biosci. 2016 Nov] PubMed

Temporal self-regulation of transposition through host-independent transposase rodlet formation. [Nucleic Acids Res. 2017 Jan] PubMed

A comprehensive approach to expression of L1 loci. [Nucleic Acids Res. 2016 Nov] PubMed

Close ecological relationship among species facilitated horizontal transfer of retrotransposons. [BMC Evol Biol. Oct 2016] PubMed

In vivo continuous evolution of genes and pathways in yeast. [Nat Commun. Oct 2016] PubMed

Mechanism for DNA transposons to generate introns on genomic scales. [Nature. Oct 2016] PubMed

The Functionality of Minimal PiggyBac Transposons in Mammalian Cells. [Mol Ther Nucleic Acids. Oct 2016] PubMed

Autonomous replication of the conjugative transposon Tn916. [J Bacteriol. Oct 2016] PubMed

Sleeping Beauty transposition: from biology to applications. [Crit Rev Biochem Mol Biol. Oct 2016] PubMed

LINEs between species: Evolutionary dynamics of LINE-1 retrotransposons across the eukaryotic tree of life. [Genome Biol Evol. Oct 2016] PubMed

Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis. [Methods Mol Biol. 2017] PubMed

Assembly and transfer of tripartite integrative and conjugative genetic elements. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Retrotransposon-mediated aluminum tolerance through enhanced expression of the citrate transporter OsFRDL4. [Plant Physiol. Oct 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

Profiling Transposable Elements and Their Epigenetic Effects in Non-model Species. [Methods Mol Biol. 2017] PubMed

Genomics and the evolution of antibiotic resistance. [Ann N Y Acad Sci. Oct 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

p53 in the game of transposons. [Bioessays. Nov 2016] PubMed

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Assembly and transfer of tripartite integrative and conjugative genetic elements. [Proc Natl Acad Sci U S A. 2016 Oct] PubMed

The Evolution of Line-1 in Vertebrates. [Genome Biol Evol. Oct 2016] PubMed

Drug resistant integrase mutants cause aberrant HIV integrations. [Retrovirology. Sep 2016] PubMed

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila. [Proc Natl Acad Sci U S A. Oct 2016] PubMed

Convergent evolution of tRNA gene targeting preferences in compact genomes. [Mob DNA. Aug 2016] PubMed

Protecting genome integrity during CRISPR immune adaptation. [Nat Struct Mol Biol. Oct 2016] PubMed

Sequence Assembly of Yarrowia lipolytica Strain W29/CLIB89 Shows Transposable Element Diversity. [PLoS One. Sep 2016] PubMed

L1-associated genomic regions are deleted in somatic cells of the healthy human brain. [Nat Neurosci. Sep 2016] PubMed

The flow of the gibbon LAVA element is facilitated by the LINE-1 retrotransposition machinery. [Genome Biol Evol. Sep 2016] PubMed

p53 in the game of transposons. [Bioessays. Sep 2016] PubMed

Helitron-like transposons contributed to the mating system transition from out-crossing to self-fertilizing in polyploid Brassica napus L. [Sci Rep. Sep 2016] PubMed

Casposon integration shows strong target site preference and recapitulates protospacer integration by CRISPR-Cas systems.[Nucleic Acids Res. Sep 2016] PubMed

ADAR1 restricts LINE-1 retrotransposition. [Nucleic Acids Res. Sep 2016] PubMed

TRT, a Vertebrate and Protozoan Tc1-Like Transposon: Current Activity and Horizontal Transfer. [Genome Biol Evol. Oct 2016] PubMed

Restricting retrotransposons: a review. [Mob DNA. Aug 2016] PubMed

Piwi Modulates Chromatin Accessibility by Regulating Multiple Factors Including Histone H1 to Repress Transposons. [Mol Cell. Aug 2016] PubMed

HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis. [Cell. Aug 2016] PubMed

Direct interrogation of the role of H3K9 in metazoan heterochromatin function. [Genes Dev. Aug 2016] PubMed

Production of Small Non-coding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster. [Genetics. Aug 2016] PubMed

Rolling-circle amplification of centromeric Helitrons in plant genomes. [Plant J. Aug 2016] PubMed

Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites. [Nucleic Acids Res. Aug 2016] PubMed

The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes. [Genome Biol Evol. Sep 2016] PubMed

Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome. [Mob DNA. Jul 2016] PubMed

Genome-wide characterization of non-reference transposons in crops suggests non-random insertion. [BMC Genomics. Aug 2016] PubMed

Identification of polymorphic SVA retrotransposons using a mobile element scanning method for SVA (ME-Scan-SVA). [Mob DNA. Jul 2016] PubMed

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. [Nat Biotechnol. Sep 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. June 2016] PubMed

Experimental single-strain mobilomics reveals events that shape pathogen emergence. [Nucleic Acids Res. July 2016] PubMed

Nuclear Noncoding RNAs and Genome Stability. [Mol Cell. July 2016] PubMed

Group II Intron Self-Splicing. [Annu Rev Biophys. July 2016] PubMed

The mechanism of ϕC31 integrase directionality: experimental analysis and computational modelling. [Nucleic Acids Res. July 2016] PubMed

CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. [EMBO Rep. July 2016] PubMed

Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3. [Viruses. July 2016] PubMed

APOBEC3DE Inhibits LINE-1 Retrotransposition by Interacting with ORF1p and Influencing LINE Reverse Transcriptase Activity. [PLoS One. July 2016] PubMed

Virus-like attachment sites as structural landmarks of plants retrotransposons. [Mob DNA. July 2016] PubMed

A pair of transposon-derived proteins regulate active DNA demethylation in Arabidopsis. [EMBO J. July 2016] PubMed

Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma. [Proc Natl Acad Sci USA. May 2016] PubMed

Methods for accurate quantification of LTR-retrotransposon copy number using short-read sequence data: a case study in Sorghum. [Mol Genet Genomics. June 2016] PubMed

Transposable Elements versus the Fungal Genome: Impact on Whole-Genome Architecture and Transcriptional Profiles. [PLoS Genet. June 2016] PubMed

Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination. [Cell. June 2016] PubMed

PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice. [Sci Rep. June 2016] PubMed

Repetitive element hypermethylation in multiple sclerosis patients. [BMC Genet. June 2016] PubMed

CRISPR Outsourcing: Commissioning IHF for Site-Specific Integration of Foreign DNA at the CRISPR Array. [Mol Cell. June 2016] PubMed

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma. [Hum Mutat. June 2016] PubMed

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen. [Genome Res. June 2016] PubMed

Retrozymes are a unique family of non-autonomous retrotransposons with hammerhead ribozymes that propagate in plants through circular RNAs. [Genome Biol. June 2016] PubMed

Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization. [Genetics. June 2016] PubMed

Analysis of tandem gene copies in maize chromosomal regions reconstructed from long sequence reads. [Proc Natl Acad Sci USA. June 2016] PubMed

Evidence of G.O.D.'s Miracle: Unearthing a RAG Transposon. [Cell. June 2016] PubMed

Structure of a group II intron in complex with its reverse transcriptase. [Nat Struct Mol Biol. May 2016] PubMed

Genomic analysis of mouse VL30 retrotransposons. [Mob DNA. May 2016] PubMed

Roles for retrotransposon insertions in human disease. [Mob DNA. May 2016] PubMed

A bend, flip and trap mechanism for transposon integration. [eLife. May 2016] PubMed

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. [Genome Res. Jun 2016] PubMed

Quantitative Insertion-site Sequencing (QIseq) for high throughput phenotyping of transposon mutants. [Genome Res. May 2016] PubMed

Next-generation sequencing-based detection of germline L1-mediated transductions. [BMC Genomics. May 2016] PubMed

DjPiwiB: A Rich Nuclear Inheritance for Descendants of Planarian Stem Cells. [Dev Cell. May 2016] PubMed

Inheritance of a Nuclear PIWI from Pluripotent Stem Cells by Somatic Descendants Ensures Differentiation by Silencing Transposons in Planarian. [Dev Cell. May 2016] PubMed

DNA Transposition at Work. [Chem Rev. May 2016] PubMed

Exploration of the Drosophila buzzatii transposable element content suggests underestimation of repeats in Drosophila genomes. [BMC Genomics. May 2016] PubMed

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen. [BMC Med Genomics. Apr 2016] PubMed

Alternative Computational Analysis Shows No Evidence for Nucleosome Enrichment at Repetitive Sequences in Mammalian Spermatozoa. [Dev Cell. Apr 2016] PubMed

Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. [Aging Cell. Apr 2016] PubMed

Alu SINE analyses of 3,000-year-old human skeletal remains: a pilot study. [Mob DNA. Apr 2016] PubMed

The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations. [Mob DNA. Apr 2016] PubMed

LINE-1-like retrotransposons contribute to RNA-based gene duplication in dicots. [Sci Rep. Apr 2016] PubMed

Brujita Integrase: A simple, arm-less, directionless, and promiscuous tyrosine integrase system. [J Mol Biol. Apr 2016] PubMed

Identification and analysis of integrons and cassette arrays in bacterial genomes. [Nucleic Acids Res. Apr 2016] PubMed

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes. [Nat Commun. Mar 2016] PubMed

GENETICS. A copy-and-paste gene regulatory network. [Science. 2016 Mar] PubMed

Regulatory evolution of innate immunity through co-option of endogenous retroviruses.  [Science. Mar 2016] PubMed

Read count-based method for high-throughput allelic genotyping of transposable elements and structural variants. [BMC Genomics. Jul 2015] PubMed

Both exact target site sequence and long poly(A) tail are required for precise insertion of the 18S rDNA-specific non-long terminal repeat retrotransposon R7Ag. [Mol Cell Biol. Mar 2016] PubMed

Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. [Proc Natl Acad Sci U S A. Mar 2016] PubMed

Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci. [Elife. Mar 2016] PubMed

Multitasking of the piRNA Silencing Machinery: Targeting Transposable Elements and Foreign Genes in the Bdelloid Rotifer Adineta vaga. [Genetics. Mar 2016] PubMed

Immune responses to endogenous retroelements: taking the bad with the good. [Nat Rev Immunol. Mar 2016] PubMed

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering. [Nat Commun. Mar 2016] PubMed

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites. [J Vis Exp. Mar 2016] PubMed

Transposon Calling Cards. [Cold Spring Harb Protoc. Feb 2016] PubMed

Genome ARTIST: a robust, high-accuracy aligner tool for mapping transposon insertions and self-insertions. [Mob DNA. Feb 2016] PubMed

How retrotransposons shape genome regulation.[Curr Opin Genet Dev. Feb 2016] PubMed

Group II introns: versatile ribozymes and retroelements. [Wiley Interdiscip Rev RNA. Feb 2016]. PubMed

Crystal structure of the Rous sarcoma virus intasome. [Nature. Feb 2016] PubMed

Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. [Nature. Feb 2016] PubMed

Transposons and Retrotransposons. [Methods in Molecular Biology. Volume 1400 2016] Springer

Biochemical Characterization of Kat1: a Domesticated hAT-Transposase that Induces DNA Hairpin Formation and MAT-Switching. [Sci Rep. Feb 2016] PubMed

Regulating retrotransposon activity through the use of alternative transcription start sites. [EMBO Rep. Feb 2016] PubMed

Resolving rates of mutation in the brain using single-neuron genomics. [Elife. Feb 2016] PubMed

Retrotransposons as regulators of gene expression. [Science. Feb 2016] PubMed

High-Throughput Genetic Screens Identify a Large and Diverse Collection of New Sporulation Genes in Bacillus subtilis. [PLoS Biol. Jan 2016] PubMed

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. [Nat Commun. Jan 2016] PubMed

Transposable element detection from whole genome sequence data. [Mob DNA. Dec 2015] PubMed

Genome-Wide Profiling Reveals Remarkable Parallels Between Insertion Site Selcetion Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4+ T Cells. [Mol Ther. Jan 2016] PubMed

Recent mobility of casposons, self-synthesizing transposons at the origin of the CRISPR-Cas immunity. [Genome Biol Evol. Jan 2016] PubMed

Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks. [Cold Spring Harb Symp Quant Biol. Jan 2016] PubMed

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins. [Cell. Jan 2016] PubMed

Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance. [Front Genet. Jan 2016] PubMed

Ty1-Integrase interacts with RNA Polymerase III specific subcomplexes to promote insertion of Ty1 elements upstream of Pol III-transcribed genes. [J Biol Chem. Jan 2016] PubMed

The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries. [J.Bioinformatics Jan 2016] PubMed

Phylogenomic analysis reveals genome-wide purifying selection on TBE transposons in the ciliate Oxytricha [Mob DNA. Jan 2016] PubMed

An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. [Elife. Jan 2016] PubMed

Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline. [Curr Opin Genet Dev. Jan 2016] PubMed

Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. [G3 (Bethesda). Jan 2016] PubMed

Systematic identification of factors for provirus silencing in embryonic stem cells. [Cell. Sep 2015] PubMed

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. [PLoS Genet. Dec 2015] PubMed

Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation. [Mol Cell. Dec 2015] PubMed

Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome. [Mol Cell. Dec 2015] PubMed

A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces. [Curr Genet. Dec 2015] PubMed

Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. [Mob DNA. Dec 2015] PubMed

Comprehensive ex vivo transposon mutagenesis identifies genes that promote growth factor independence and leukemogenesis. [Cancer Res. Dec 2015] PubMed

Conservative site-specific and single-copy transgenesis in human LINE-1 elements. [Nucleic Acids Res. Dec 2015] PubMed

VHICA, a new method to discriminate between vertical and horizontal transposon transfer: application to the mariner family within Drosophila. [Mol Biol Evol. Dec 2015] PubMed

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection. [PLoS Pathog. Dec 2015] PubMed

piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts. [Nucleic Acids Res. Dec 2015] PubMed

p53 genes function to restrain mobile elements. [Genes Dev. Dec 2015] PubMed

The making of a genomic parasite - the Mothra family sheds light on the evolution of Helitrons in plants. [Mob DNA. Dec 2015] PubMed

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. [Science. Dec 2015] PubMed

ISC, a novel group of bacterial and archaeal DNA transposons that encode Cas9 homologs. [J Bacteriol. Dec 2015] PubMed

A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition [Mol Cell. Nov 2015] PubMed

Retrotransposition and Crystal Structure of an Alu RNP in the Ribosome-Stalling Conformation [Mol Cell. Nov 2015] PubMed

The casposon-encoded Cas1 protein from Aciduliprofundum boonei is a DNA integrase that generates target site duplications [NAR. Nov 2015] PubMed

Inference of Transposable Element Ancestry [PLOS Genetics. Nov 2015] PubMed

Unique transposon landscapes are pervasive across Drosophila melanogaster genomes [NAR. Nov 2015] PubMed

Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages [PLoS Pathog. Nov 2015] PubMed

RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens [Genome Res. Nov 2015] PubMed

DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes [Mol Biol Evol. Nov 2015] PubMed

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons [PNAS. Nov 2015] PubMed

Response of transposable elements to environmental stressors [Mutat Res Rev Mutat Res. Jul-Sep 2015] PubMed

Antisense Transcription of Retrotransposons in Drosophila: The Origin of Endogenous Small Interfering RNA Precursors [Genetics. Nov 2015] PubMed

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse [PLoS Genet. Oct 2015] PubMed

Holocentromeres in Rhynchospora are associated with genome-wide centromere-specific repeat arrays interspersed among euchromatin [PNAS. Nov 2015] PubMed

Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity [Cell. Oct 2015] PubMed

Transposon sequencing: methods and expanding applications [Appl Microbiol Biotechnol. Oct 2015] PubMed

Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution [BMC Genomics. Oct 2015] PubMed

Tools for Targeted Genome Engineering of Established Drosophila Cell Lines [Genetics. Oct 2015] PubMed

Alternative Transposition Generates New Chimeric Genes and Segmental Duplications at the Maize p1 Locus [Genetics. Oct 2015] PubMed

The Ty1 Retrotransposon Restriction Factor p22 Targets Gag [PLoS Genet. Oct 2015] PubMed

Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides [Science. Oct 2015] PubMed

Arrested replication forks guide retrotransposon integration [Science. Sep 2015] PubMed

Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes [PLoS Genet. Sep 2015] PubMed

Genomic DNA transposition induced by human PGBD5 [Elife. Sep 2015] PubMed

Profiling the RNA editomes of wild-type C. elegans and ADAR mutants [Genome Res. Jan 2015] PubMed

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression [Science. Oct 2015] PubMed

Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians [PLoS Genet. Sep 2015] PubMed

TE-Tracker: systematic identification of transposition events through whole-genome resequencing [BMC Bioinformatics. Nov 2014] PubMed

Enhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest [Cell. Sep 2015] PubMed

Conformational toggling controls target site choice for the heteromeric transposase element Tn7 [Nucleic Acids Res. Sep 2015] PubMed

Single Nucleotide Specific Targeting of the Tf1 Retrotransposon Promoted by the DNA-Binding Protein Sap1 of Schizosaccharomyces pombe [Genetics. Sep 2015] PubMed

Loss of Karma transposon methylation underlies the mantled somaclonal variant of oil palm [Nature. Sep 2015] PubMed

miR-128 represses L1 retrotransposition by binding directly to L1 RNA [Nat Struct Mol Biol. Oct 2015] PubMed

Sequence Analysis and Characterization of Active Human Alu subfamilies Based on the 1000 Genomes Pilot Project [Genome Biol Evol. Aug 2015] PubMed

Preferential retrotransposition in aging yeast mother cells is correlated with increased genome instability [DNA Repair Aug 2015] PubMed

Organization and evolution of transposable elements along the bread wheat chromosome 3B [Genome Biology Dec 2014] PubMed

Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions [Genome Biology Dec 2014] PubMed

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma [PNAS Sep 2015] PubMed

Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition [Elife. Aug 2015] PubMed

An Atypical AAA+ ATPase Assembly Controls Efficient Transposition through DNA Remodeling and Transposase Recruitment [Cell. Aug 2015] PubMed

Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation [PLoS Genet. Aug 2015] PubMed

piRNAs Are Associated with Diverse Transgenerational Effects on Gene and Transposon Expression in a Hybrid Dysgenic Syndrome of D. virilis [PLoS Genet. Aug 2015] PubMed

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma [Nature Med. Sep 2015] PubMed

MIR retrotransposon sequences provide insulators to the human genome [PNAS. Jul 2015] PubMed

Tn-seq of Caulobacter crescentus under uranium stress reveals genes essential for detoxification and stress tolerance [J Bacteriol. Jul 2015] PubMed

LINE-1 Retroelements Get ZAPped! [PLoS Genet. Jul 2015] PubMed

ZmMBD101 is a DNA binding protein that maintains Mutator elements chromatin in a repressive state in maize [Plant Cell Environ. Jul 2015] PubMed

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation [PLoS Genet. Jul 2015] PubMed

Repbase Update, a database of repetitive elements in eukaryotic genomes [Mobile DNA. Jun 2015] PubMed

The diversification of PHIS transposon superfamily in eukaryotes [Mobile DNA. Jun 2015] PubMed

Distinct sets of PIWI proteins produce arbovirus and transposon-derived piRNAs in Aedes aegypti mosquito cells [Nucleic Acids Res. Jun 2015] PubMed

Structural basis for retroviral integration into nucleosomes [Nature. Jul 2015] PubMed

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery [Curr Opin Genet Dev. Feb 2015] PubMed

A Transposable Element within the Non-canonical Telomerase RNA of Arabidopsis thaliana Telomerase in Response to DNA Damage [PLoS Genet. Jun 2015] PubMed

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination [Genes Dev. Jun 2015] PubMed

The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline [EMBO Rep. Jun 2015] PubMed

Evolution of group II introns [Mobile DNA. Apr 2015] PubMed

N(6)-methyladenine DNA modification in Drosophila [Cell. May 2015] PubMed

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition [PLoS Genet. May 2015] PubMed

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells [Nature. May 2015] PubMed

Rapid quantification of mutant fitness in diverse bacteria by sequencing randomly bar-coded transposons [MBio. May 2015] PubMed

Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production [Science. May 2015] PubMed

Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis [Science. May 2015] PubMed

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes [Sci Rep. May 2015] PubMed

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis [Nat Genet. May 2015] PubMed

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites [Genome Res. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals [Genome Biology. May 2015] PubMed

Mosaic genome of endobacteria in arbuscular mycorrhizal fungi: Transkingdom gene transfer in an ancient mycoplasma-fungus association [PNAS. May 2015] PubMed

Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration [Science. May 2015] PubMed

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses [Genes Dev. Mar 2015] PubMed

Evolution of adaptive immunity from transposable elements combined with innate immune systems [Nat Rev Genet. Mar 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma [Nat Genet. May 2015] PubMed

Phosphorylation of ORF1p is required for L1 retrotransposition [PNAS. Apr 2015] PubMed

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells [Nature. Jun 2015] PubMed

Mobile DNA welcomes new Editors-in-Chief, Marlene Belfort and Haig Kazazian - a BioMed Central blog biomedcentral.com

Ubiquitous l1 mosaicism in hippocampal neurons [Cell. Apr 2015] PubMed

Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams [Cell. Apr 2015] PubMed

Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage [Biol Trace Elem Res. Mar 2015] PubMed